The Impact of Sprint Interval Training Frequency on Blood Glucose Control and Physical Function of Older Adults (2020)
Journal Article
Adamson, S., Kavaliauskas, M., Lorimer, R., & Babraj, J. (2020). The Impact of Sprint Interval Training Frequency on Blood Glucose Control and Physical Function of Older Adults. International Journal of Environmental Research and Public Health, 17(2), 454. https://doi.org/10.3390/ijerph17020454

Exercise is a powerful tool for improving health in older adults, but the minimum frequency required is not known. This study sought to determine the effect of training frequency of sprint interval training (SIT) on health and physical function in ol... Read More about The Impact of Sprint Interval Training Frequency on Blood Glucose Control and Physical Function of Older Adults.

In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography (2019)
Journal Article
Madi, K., Staines, K., Bay, B., Javaheri, B., Geng, H., Bodey, A., Cartmell, S., Pitsillides, A., & Lee, P. (2020). In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography. Nature Biomedical Engineering, 4(3), 343-354. https://doi.org/10.1038/s41551-019-0477-1

Imaging techniques for quantifying changes in the hierarchical structure of deforming joints are constrained by destructive sample treatments, sample-size restrictions and lengthy scan times. Here, we report the use of fast low-dose pink-beam synchro... Read More about In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography.

A Biomechanical Analysis of British Army Foot-Drill: Implications of Lower-Extremity Musculoskeletal Injury in Age-matched Civilian Men and Women (2019)
Thesis
Rawcliffe, A. J. A Biomechanical Analysis of British Army Foot-Drill: Implications of Lower-Extremity Musculoskeletal Injury in Age-matched Civilian Men and Women. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/2090019

British Army foot-drill may be a risk factor for musculoskeletal (MSK) injury. However, limited empirical research exists quantifying lower-extremity risk factors of foot-drill in men and women. To better understand and provide greater insight into t... Read More about A Biomechanical Analysis of British Army Foot-Drill: Implications of Lower-Extremity Musculoskeletal Injury in Age-matched Civilian Men and Women.

Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure (2019)
Journal Article
Kirkwood, L. A., Taylor, M. D., Ingram, L. A., Malone, E., & Florida-James, G. D. (2019). Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure. Journal of Science and Cycling, 8(1), 18-25. https://doi.org/10.28985/1906.jsc.04

Limited information is currently available regarding the hand-arm vibration (HAV) exposure 5 for professional off-road cyclists. Previous reports have suggested that commuting and 6 recreational cyclists are at risk of exceeding exposure limit values... Read More about Elite mountain bike enduro competition: a study of rider hand-arm vibration exposure.

Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. (2019)
Journal Article
Montgomery, R., Paterson, A., Williamson, C., Florida-James, G., & Ross, M. D. (2019). Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. Frontiers in Physiology, https://doi.org/10.3389/fphys.2019.00447

Endothelial progenitor cells (EPCs) are a vasculogenic subset of progenitors, which play a key role in maintenance of endothelial integrity. These cells are exercise-responsive, and thus exercise may play a key role in vascular repair and maintenance... Read More about Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men..

Determination of hand-transmitted vibration risk on the human (2019)
Journal Article
Maeda, S., Taylor, M., Anderson, L. C., & McLaughlin, J. (2019). Determination of hand-transmitted vibration risk on the human. International Journal of Industrial Ergonomics, 70, 28-37. https://doi.org/10.1016/j.ergon.2019.01.002

Objective: The purpose of this paper is to examine the effectiveness of the proposed consideration for hand-transmitted vibration measurement on the human. Method: To obtain the temporary threshold shift (TTS) in the fingertip vibrotactile perception... Read More about Determination of hand-transmitted vibration risk on the human.

Circulating angiogenic cell response to sprint interval and continuous exercise. (2019)
Journal Article
O'Carroll, L., Wardrop, B., Murphy, R. P., Ross, M. D., & Harrison, M. (2019). Circulating angiogenic cell response to sprint interval and continuous exercise. European Journal of Applied Physiology, 119(3), 743-752. https://doi.org/10.1007/s00421-018-04065-7

Although commonly understood as immune cells, certain T lymphocyte and monocyte subsets have angiogenic potential, contributing to blood vessel growth and repair. These cells are highly exercise responsive and may contribute to the cardiovascular ben... Read More about Circulating angiogenic cell response to sprint interval and continuous exercise..

Low Volume, Home-Based Weighted Step Exercise Training Can Improve Lower Limb Muscle Power and Functional Ability in Community-Dwelling Older Women (2019)
Journal Article
Mair, J. L., De Vito, G., & Boreham, C. A. (2019). Low Volume, Home-Based Weighted Step Exercise Training Can Improve Lower Limb Muscle Power and Functional Ability in Community-Dwelling Older Women. Journal of Clinical Medicine, 8(1), 41. https://doi.org/10.3390/jcm8010041

Stepping exercise can be used as a scalable form of high intensity exercise to enhance important aspects of physical fitness in older populations. The addition of supplementary weights increases the resistive element of stepping, with the potential f... Read More about Low Volume, Home-Based Weighted Step Exercise Training Can Improve Lower Limb Muscle Power and Functional Ability in Community-Dwelling Older Women.

Determination of ankle and metatarsophalangeal stiffness during walking and jogging (2018)
Journal Article
Mager, F., Richards, J., Hennies, M., Dötzel, E., Chohan, A., Mbuli, A., & Capanni, F. (2018). Determination of ankle and metatarsophalangeal stiffness during walking and jogging. Journal of Applied Biomechanics, 34(6), 448-453. https://doi.org/10.1123/jab.2017-0265

Forefoot stiffness has been shown to influence joint biomechanics. However, little or no data exist on metatarsophalangeal stiffness. Twenty-four healthy rearfoot strike runners were recruited from a staff and student population at the University of... Read More about Determination of ankle and metatarsophalangeal stiffness during walking and jogging.

Providing pupils autonomous use of sit-stand desks; behaviour changes and teacher and pupil opinion following an 8 week intervention (2018)
Presentation / Conference Contribution
Fowler, S., Pitkethly, A., Booth, J., Sproule, J., & Hutson, D. (2018, October). Providing pupils autonomous use of sit-stand desks; behaviour changes and teacher and pupil opinion following an 8 week intervention. Presented at 7th International Society for Physical Activity and Health Congress, London, UK

Parallel oral session : Wednesday 17th October

FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression (2017)
Journal Article
Ikpegbu, E., Basta, L., Clements, D. N., Fleming, R., Vincent, T. L., Buttle, D. J., Pitsillides, A. A., Staines, K. A., & Farquharson, C. (2018). FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression. Journal of Cellular Physiology, 233(7), 5334-5347. https://doi.org/10.1002/jcp.26345

E11/podoplanin is critical in the early stages of osteoblast-to-osteocyte transitions (osteocytogenesis) however the upstream events which regulate E11 expression are unknown. The aim of this study was to examine the effects of FGF-2 on E11-mediated... Read More about FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression.

Incidence of postoperative atrial fibrillation recurrence in patients discharged in sinus rhythm after cardiac surgery: a systematic review and meta-analysis (2017)
Journal Article
Lowres, N., Mulcahy, G., Jin, K., Gallagher, R., Neubeck, L., & Freedman, B. (2018). Incidence of postoperative atrial fibrillation recurrence in patients discharged in sinus rhythm after cardiac surgery: a systematic review and meta-analysis. Interactive Cardiovascular and Thoracic Surgery, 26(3), 504-511. https://doi.org/10.1093/icvts/ivx348

Post-operative atrial fibrillation (POAF) is associated with increased stroke risk and mortality post-discharge. POAF is often considered transient, however recurrence is likely under-recognized as symptoms are an unreliable guide. Surveillance post-... Read More about Incidence of postoperative atrial fibrillation recurrence in patients discharged in sinus rhythm after cardiac surgery: a systematic review and meta-analysis.

Promotion of physical activity interventions for community dwelling older adults: A systematic review of reviews (2017)
Journal Article
Zubala, A., MacGillivray, S., Frost, H., Kroll, T., Skelton, D. A., Gavine, A., Gray, N. M., Toma, M., & Morris, J. (2017). Promotion of physical activity interventions for community dwelling older adults: A systematic review of reviews. PLOS ONE, 12(7), Article e0180902. https://doi.org/10.1371/journal.pone.0180902

Objectives While there is strong evidence that regular participation in physical activity (PA) brings numerous health benefits to older adults, and interventions to effectively promote PA are being developed and tested, the characteristics and compon... Read More about Promotion of physical activity interventions for community dwelling older adults: A systematic review of reviews.

The expression of the chloride co-transporters NKCC1 and KCC2 is reversed in the penumbra following (2017)
Presentation / Conference Contribution
Baudel, M., Rae, M., Fraser, J., & Poole, A. (2017, April). The expression of the chloride co-transporters NKCC1 and KCC2 is reversed in the penumbra following. Presented at BNA 2017

Stroke is one of the major causes of death and disability worldwide. The harm caused by the interruption of blood flow to the brain unfolds in the subsequent hours and days, so it is critical to identify new therapeutic targets that could reduce neur... Read More about The expression of the chloride co-transporters NKCC1 and KCC2 is reversed in the penumbra following.

Association between bisphosphonate therapy and outcomes from rehabilitation in older people (2017)
Journal Article
Goodbrand, J. A., Hughes, L. D., Cochrane, L., Donnan, P. T., McGilchrist, M., Frost, H., McMurdo, M. E., & Witham, M. D. (2017). Association between bisphosphonate therapy and outcomes from rehabilitation in older people. Archives of Gerontology and Geriatrics, 70, 195-200. https://doi.org/10.1016/j.archger.2017.01.017

Background Bisphosphonate therapy may have actions beyond bone, including effects on cardiovascular, immune and muscle function. We tested whether bisphosphonate treatment is associated with improved outcomes in older people undergoing inpatient reh... Read More about Association between bisphosphonate therapy and outcomes from rehabilitation in older people.

Vascular Ageing and Exercise: Focus on Cellular Reparative Processes (2016)
Journal Article
Ross, M. D., Malone, E., & Florida-James, G. (2016). Vascular Ageing and Exercise: Focus on Cellular Reparative Processes. Oxidative Medicine and Cellular Longevity, 2016, 1-15. https://doi.org/10.1155/2016/3583956

Ageing is associated with an increased risk of developing noncommunicable diseases (NCDs), such as diabetes and cardiovascular disease (CVD). The increased risk can be attributable to increased prolonged exposure to oxidative stress. Often, CVD is pr... Read More about Vascular Ageing and Exercise: Focus on Cellular Reparative Processes.

Chloride co-transporters as possible therapeutic targets for stroke (2016)
Journal Article
Martín-Aragón Baudel, M. A. S., Martín-Aragón Baudel, M. A. S., Poole, A. V., & Darlison, M. G. (2017). Chloride co-transporters as possible therapeutic targets for stroke. Journal of Neurochemistry, 140(2), 195-209. https://doi.org/10.1111/jnc.13901

Stroke is one of the major causes of death and disability worldwide. The major type of stroke is an ischaemic one, which is caused by a blockage that interrupts blood flow to the brain. There are currently very few pharmacological strategies to red... Read More about Chloride co-transporters as possible therapeutic targets for stroke.

Opportunistic screening to detect atrial fibrillation in Aboriginal adults in Australia (2016)
Journal Article
Gwynne, K., Flaskas, Y., O'Brien, C., Jeffries, T. L., McCowen, D., Finlayson, H., Martin, T., Neubeck, L., & Freedman, B. (2016). Opportunistic screening to detect atrial fibrillation in Aboriginal adults in Australia. BMJ Open, 6(11), Article e013576. https://doi.org/10.1136/bmjopen-2016-013576

Introduction There is a 10-year gap in life expectancy between Aboriginal and non-Aboriginal Australians. The leading cause of death for Aboriginal Australians is cardiovascular disease, including myocardial infarction and stroke. Although atrial fib... Read More about Opportunistic screening to detect atrial fibrillation in Aboriginal adults in Australia.

Models of ex vivo explant cultures: applications in bone research (2016)
Journal Article
Marino, S., Staines, K. A., Brown, G., Howard-Jones, R. A., & Adamczyk, M. (2016). Models of ex vivo explant cultures: applications in bone research. BoneKEy Reports, 5, 818. https://doi.org/10.1038/bonekey.2016.49

Ex vivo explant culture models are powerful tools in bone research. They allow investigation of bone and cartilage responses to specific stimuli in a controlled manner that closely mimics the in vivo processes. Because of limitations in
obtaining he... Read More about Models of ex vivo explant cultures: applications in bone research.

Antiviral host defence peptides. (2016)
Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016). Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents (57-94). Springer. https://doi.org/10.1007/978-3-319-32949-9_3

The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The antiviral activity of cationic host defence peptides is of significant interest... Read More about Antiviral host defence peptides..