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Welcome to Edinburgh Napier Research Repository

The ‘Research Repository’ is the open access institutional repository of Edinburgh Napier University. It contains examples of research outputs produced by staff and research students, as well as related information about the university's funded projects and staff research interests.

Whenever possible, refereed documents accepted for publication, or finished artistic compositions presented in public, will be made available here in full digital format, and hyperlinks to standard published versions will be provided. Any questions about submissions to the repository or problems with access to any of its content should be sent to the Repository Team at repository@napier.ac.uk



Latest Additions

Erratum to: ‘Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial’ (2016)
Journal Article
Hellyer, T. P., Anderson, N. H., Parker, J., Dark, P., Van Den Broeck, T., Singh, S., …Simpson, A. J. (2016). Erratum to: ‘Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial’. Trials, 17(1), Article 465. https://doi.org/10.1186/s13063-016-1594-8

[Abstract unavailable.]

Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial (2016)
Journal Article
Hellyer, T. P., Anderson, N. H., Parker, J., Dark, P., Van Den Broeck, T., Singh, S., …Simpson, A. J. (2016). Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial. Trials, 17(1), Article 318. https://doi.org/10.1186/s13063-016-1442-x

Background Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage... Read More about Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial.

Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention (2018)
Journal Article
Richards-Belle, A., Mouncey, P. R., Wade, D., Brewin, C. R., Emerson, L. M., Grieve, R., …Rowan, K. M. (2018). Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention. BMJ Open, 8(2), Article e020908. https://doi.org/10.1136/bmjopen-2017-020908

Introduction Acute psychological stress, as well as unusual experiences including hallucinations and delusions, are common in critical care unit patients and have been linked to post-critical care psychological morbidity such as post-traumatic stress... Read More about Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention.

Cognitive ageing and experience of playing a musical instrument (2023)
Journal Article
Okely, J. A., Cox, S. R., Deary, I. J., Luciano, M., & Overy, K. (in press). Cognitive ageing and experience of playing a musical instrument. Psychology and Aging,

Musical instrument training has been found to be associated with higher cognitive performance in older age. However, it is not clear whether this association reflects a reduced rate of cognitive decline in older age (differential preservation), and/o... Read More about Cognitive ageing and experience of playing a musical instrument.

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation (2019)
Journal Article
Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N., Conway Morris, A., Singh, S., …Simpson, A. J. (2020). Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation. Lancet Respiratory Medicine, 8(2), 182-191. https://doi.org/10.1016/S2213-2600%2819%2930367-4

Background Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse of antibiotics. Low concentrations of IL-1β and IL-8 in bronchoalveolar lavage f... Read More about Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation.