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Outputs (41)

ExtraCECI: a community-based person-centred-enhanced care intervention to improve the quality of life and person-centred outcomes for people living with HIV/AIDS in Ghana—protocol for cluster randomised controlled trial (2025)
Journal Article
Abboah-Offei, M., Elsey, H., Nkhoma, K. B., Abboah-Offei, S., Keding, A., Fenty, J., Yakimova, A., Hewitt, C., Dzansi, G., Senoo-Dogbey, V. E., Ayisi Addo, S., Akazili, J., Ayim, A., & Harding, R. (2025). ExtraCECI: a community-based person-centred-enhanced care intervention to improve the quality of life and person-centred outcomes for people living with HIV/AIDS in Ghana—protocol for cluster randomised controlled trial. BMJ Open, 15(5), Article e102692. https://doi.org/10.1136/bmjopen-2025-102692

Introduction - People living with HIV/AIDS (PLWHA) have complex physical, psychological, social and spiritual needs following diagnosis and poorer health-related quality of life than the general population. Holistic assessment and care delivery incor... Read More about ExtraCECI: a community-based person-centred-enhanced care intervention to improve the quality of life and person-centred outcomes for people living with HIV/AIDS in Ghana—protocol for cluster randomised controlled trial.

Biomarkers of insulin resistance and their performance as predictors of treatment response in overweight adults (2025)
Journal Article
Brogan, R. J., Rooyackers, O., Phillips, B. E., Twelkmeyer, B., Ross, L. M., Atherton, P. J., Kraus, W. E., Timmons, J. A., & Gallagher, I. J. (online). Biomarkers of insulin resistance and their performance as predictors of treatment response in overweight adults. Journal of Clinical Endocrinology and Metabolism, Article dgaf285. https://doi.org/10.1210/clinem/dgaf285

Context
Insulin Resistance (IR) contributes to the pathogenesis of type 2 diabetes mellitus (T2DM) and is a risk factor for cardiovascular and neurodegenerative diseases. Amino acid and lipid metabolomic biomarkers associate with future T2DM risk i... Read More about Biomarkers of insulin resistance and their performance as predictors of treatment response in overweight adults.

Young men with intellectual disabilities’ perceptions of HPV and HPV vaccine: A qualitative study on how to communicate HPV vaccine information (2025)
Journal Article
Carnegie, E., Gray-Brunton, C., Kennedy, C., Pow, J., Willis, D., & Whittaker, A. (2025). Young men with intellectual disabilities’ perceptions of HPV and HPV vaccine: A qualitative study on how to communicate HPV vaccine information. Human Vaccines and Immunotherapeutics, 21(1), Article 2491857. https://doi.org/10.1080/21645515.2025.2491857

The success of vaccination programs relies on acceptance of recommended vaccines by communities and individuals. There is a paucity of evidence regarding how young men with intellectual disabilities actively produce or receive inclusive and accessibl... Read More about Young men with intellectual disabilities’ perceptions of HPV and HPV vaccine: A qualitative study on how to communicate HPV vaccine information.

Commentary and methodological insights: Reaching girls/women, boys/men and vulnerable groups to maximise uptake for the Human papillomavirus vaccine (2025)
Journal Article
Gray Brunton, C., Pow, J., Carnegie, E., Petrova, D., Garcia Retamero, R., Whittaker, A., & Todorova, I. (2025). Commentary and methodological insights: Reaching girls/women, boys/men and vulnerable groups to maximise uptake for the Human papillomavirus vaccine. Human Vaccines and Immunotherapeutics, 21(1), Article 2478705. https://doi.org/10.1080/21645515.2025.2478705

The human papillomavirus (HPV) vaccine has been shown to be an effective cancer-prevention vaccine against oncogenic types of the HPV virus implicated in cervical, anogenital, and oropharyngeal cancers. Since Covid-19, there are global suboptimal upt... Read More about Commentary and methodological insights: Reaching girls/women, boys/men and vulnerable groups to maximise uptake for the Human papillomavirus vaccine.

Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment] (2025)
Other
Foley, S. (2025). Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment]

An application was submitted to the Food Standards Agency (FSA) and Food Standards Scotland (FSS) in February 2021 from Bridge Farm Group. (“the applicant”) for the authorisation of cannabidiol (CBD) isolate as a novel food.

The novel food is a CB... Read More about Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment].

Technical guidance to applicants for the authorisation of Precision Bred Organisms for food and feed: Draft (07.02.2025) (2025)
Other
Foley, S. (2025). Technical guidance to applicants for the authorisation of Precision Bred Organisms for food and feed: Draft (07.02.2025)

This draft guidance describes the scientific considerations required for evaluating the safety and nutritional aspects of Precision Bred Organisms (PBOs) when seeking marketing authorisation of PBOs for use in the production of food and feed.

Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis (2025)
Journal Article
Refalo, M. C., Nuckols, G., Galpin, A. J., Gallagher, I. J., Hamilton, D. L., & Fyfe, J. J. (2025). Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis. PeerJ, 13, Article e19042. https://doi.org/10.7717/peerj.19042

Background
Muscle hypertrophy may be influenced by biological differences between males and females. This meta-analysis investigated absolute and relative changes in muscle size following resistance training (RT) between males and females and whethe... Read More about Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis.

Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling (2024)
Preprint / Working Paper
Elsharkasi, M., Villani, B., Wells, G., & Kerr, F. Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling

As a gate-keeper of anti-oxidant, anti-inflammatory and xenobiotic cell protection mechanisms, the transcription factor Nrf2 has been implicated as a promising therapeutic target for several neurodegenerative diseases, leading to the development of N... Read More about Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling.

Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa (2024)
Journal Article
Orzel, D., Ravald, H., Dillon, A., Rantala, J., Wiedmer, S. K., & Russo, G. (2024). Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa. Journal of Chromatography A, 1734, Article 465286. https://doi.org/10.1016/j.chroma.2024.465286

This study pioneers a comparison of the application of biomimetic techniques, immobilised artificial membrane liquid chromatography (IAM LC) and liposome electrokinetic capillary chromatography (LEKC), for the prediction of pulmonary drug permeabilit... Read More about Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa.

β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting (2024)
Journal Article
Baghestani, S., Haldin, C., Kosijer, P., Alam, C. M., & Toivola, D. M. (2024). β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting. American Journal of Physiology - Cell Physiology, 327(2), C462-C476. https://doi.org/10.1152/ajpcell.00123.2024

Islet β-cell dysfunction is an underlying factor for type I diabetes (T1D) development. Insulin sensing and secretion are tightly regulated in β-cells at multiple subcellular levels. The epithelial intermediate filament (IF) protein keratin (K) 8 is... Read More about β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting.

Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species. Food Standards Agency

An application was submitted to the Food Standards Agency in May 2021 from AlzChem Trostberg GmbH (“the applicant”) for the new use authorisation of an additive guanidinoacetic acid (Creamino®), under the category of ‘nutritional additives” and funct... Read More about Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species.

Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360) (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360). Food Standards Agency

An application was submitted to the Food Standards Agency in March 2021 from DSM Nutritional Products LTD (“the applicant”) for the new authorisation of an additive (ProAct 360) containing protease (subtilisin), under the category of “zootechnical ad... Read More about Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360).

Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®) (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®). Food Standards Agency

An application was submitted to the Food Standards Agency in April 2021 from Phibro Animal Health Corporation (“the applicant”) for the new authorisation of an additive (Magni-Phi®), a natural preparation of powdered dry Quillaja saponaria and dry Yu... Read More about Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®).

Safety Assessment RP416 Axtra XB (2023)
Report
Morrison, D. (2023). Safety Assessment RP416 Axtra XB. Food Standards Agency

An application was submitted to the Food Standards Agency in February 2021 by Genencor International B.V. (“the applicant”) for the authorisation of an additive (endo-1,4-betaxylanase and endo-1,3(4)-beta-glucanase - Axtra® XB), under retained regula... Read More about Safety Assessment RP416 Axtra XB.