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Outputs (35)

Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment] (2025)
Other
Foley, S. (2025). Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment]

An application was submitted to the Food Standards Agency (FSA) and Food Standards Scotland (FSS) in February 2021 from Bridge Farm Group. (“the applicant”) for the authorisation of cannabidiol (CBD) isolate as a novel food.

The novel food is a CB... Read More about Committee Advice on the safety of cannabidiol (CBD) isolate as a novel food for use in food supplements - RP354 [Food Standards Agency (FSA) and Food Standards Scotland (FSS) Regulated Product Dossier Assessment].

Technical guidance to applicants for the authorisation of Precision Bred Organisms for food and feed: Draft (07.02.2025) (2025)
Other
Foley, S. (2025). Technical guidance to applicants for the authorisation of Precision Bred Organisms for food and feed: Draft (07.02.2025)

This draft guidance describes the scientific considerations required for evaluating the safety and nutritional aspects of Precision Bred Organisms (PBOs) when seeking marketing authorisation of PBOs for use in the production of food and feed.

Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis (2025)
Journal Article
Refalo, M. C., Nuckols, G., Galpin, A. J., Gallagher, I. J., Hamilton, D. L., & Fyfe, J. J. (2025). Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis. PeerJ, 13, Article e19042. https://doi.org/10.7717/peerj.19042

Background
Muscle hypertrophy may be influenced by biological differences between males and females. This meta-analysis investigated absolute and relative changes in muscle size following resistance training (RT) between males and females and whethe... Read More about Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis.

Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling (2024)
Preprint / Working Paper
Elsharkasi, M., Villani, B., Wells, G., & Kerr, F. Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling

As a gate-keeper of anti-oxidant, anti-inflammatory and xenobiotic cell protection mechanisms, the transcription factor Nrf2 has been implicated as a promising therapeutic target for several neurodegenerative diseases, leading to the development of N... Read More about Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling.

Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa (2024)
Journal Article
Orzel, D., Ravald, H., Dillon, A., Rantala, J., Wiedmer, S. K., & Russo, G. (2024). Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa. Journal of Chromatography A, 1734, Article 465286. https://doi.org/10.1016/j.chroma.2024.465286

This study pioneers a comparison of the application of biomimetic techniques, immobilised artificial membrane liquid chromatography (IAM LC) and liposome electrokinetic capillary chromatography (LEKC), for the prediction of pulmonary drug permeabilit... Read More about Immobilised artificial membrane liquid chromatography vs liposome electrokinetic capillary chromatography: Suitability in drug/bio membrane partitioning studies and effectiveness in the assessment of the passage of drugs through the respiratory mucosa.

β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting (2024)
Journal Article
Baghestani, S., Haldin, C., Kosijer, P., Alam, C. M., & Toivola, D. M. (2024). β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting. American Journal of Physiology - Cell Physiology, 327(2), C462-C476. https://doi.org/10.1152/ajpcell.00123.2024

Islet β-cell dysfunction is an underlying factor for type I diabetes (T1D) development. Insulin sensing and secretion are tightly regulated in β-cells at multiple subcellular levels. The epithelial intermediate filament (IF) protein keratin (K) 8 is... Read More about β-Cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure, and β-cell glucose transporter 2 plasma membrane targeting.

Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species. Food Standards Agency

An application was submitted to the Food Standards Agency in May 2021 from AlzChem Trostberg GmbH (“the applicant”) for the new use authorisation of an additive guanidinoacetic acid (Creamino®), under the category of ‘nutritional additives” and funct... Read More about Assessment of the safety and efficacy of Guanidinoacetic acid (Creamino®) as a feed additive for all animal species.

Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®) (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®). Food Standards Agency

An application was submitted to the Food Standards Agency in April 2021 from Phibro Animal Health Corporation (“the applicant”) for the new authorisation of an additive (Magni-Phi®), a natural preparation of powdered dry Quillaja saponaria and dry Yu... Read More about Safety Assessment RP1047 Quillaja saponaria and Yucca schidigera (Magni-Phi®).

Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360) (2024)
Report
Morrison, D., & Wheelhouse, N. (2024). Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360). Food Standards Agency

An application was submitted to the Food Standards Agency in March 2021 from DSM Nutritional Products LTD (“the applicant”) for the new authorisation of an additive (ProAct 360) containing protease (subtilisin), under the category of “zootechnical ad... Read More about Safety Assessment RP709 protease (subtilisin) produced by Bacillus licheniformis DSM 33099 (ProAct 360).

Safety Assessment RP416 Axtra XB (2023)
Report
Morrison, D. (2023). Safety Assessment RP416 Axtra XB. Food Standards Agency

An application was submitted to the Food Standards Agency in February 2021 by Genencor International B.V. (“the applicant”) for the authorisation of an additive (endo-1,4-betaxylanase and endo-1,3(4)-beta-glucanase - Axtra® XB), under retained regula... Read More about Safety Assessment RP416 Axtra XB.

Scottish Life And Chemical Science Skills Summit (2023)
Report
Maguire, H., & Garden, C. (2023). Scottish Life And Chemical Science Skills Summit. Edinburgh, UK: Scottish Universities Life Sciences Alliance (SULSA)

The Scottish Life and Chemical Skills Summit was led and hosted by Edinburgh Napier University (ENU) with support from Skills Development Scotland (SDS) and the Scottish Universities Life Sciences Alliance (SULSA).
We would like to thank members of... Read More about Scottish Life And Chemical Science Skills Summit.

Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation (2023)
Journal Article
Duncan, W. C., Nicol, L. M., O’Hare, R., Witherington, J., Miranda, J. A., Campbell, B. K., Thomas, J. L., & Rae, M. T. (2023). Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation. Frontiers in Endocrinology, 14, Article 1285269. https://doi.org/10.3389/fendo.2023.1285269

Introduction: Polycystic ovary syndrome (PCOS) seems to be associated with increased ovarian sympathetic nerve activity and in rodent models of PCOS reducing the sympathetic drive to the ovary, through denervation or neuromodulation, improves ovulati... Read More about Development of an acute ovine model of polycystic ovaries to assess the effect of ovarian denervation.

Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland (2023)
Journal Article
Garden, C. L. P. (2023). Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland. British Journal of Biomedical Science, 80, Article 11654. https://doi.org/10.3389/bjbs.2023.11654

Biomedical sciences graduates are employed in a variety of different settings and form a significant part of the Life Sciences sector workforce in Scotland. Their degrees should equip them with the skills and knowledge to not only enter the workplace... Read More about Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland.

Exploring what Student Engagement means for Biology Educators: What can Gamification Research tell us? (2023)
Presentation / Conference Contribution
Garden, C. L. P. (2023, July). Exploring what Student Engagement means for Biology Educators: What can Gamification Research tell us?. Presented at Society for Experimental Biology Centenary Conference, Edinburgh

The way we teach experimental biology continues to change as we recover, and learn lessons, from the COVID-19 pandemic. We often discuss student engagement as part of this process, but what does this mean in practice? How can we tell if students are... Read More about Exploring what Student Engagement means for Biology Educators: What can Gamification Research tell us?.