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Ovine trophoblasts express cathelicidin host defence peptide in response to infection (2016)
Journal Article
Coyle, C., Wheelhouse, N., Jacques, M., Longbottom, D., Svoboda, P., Pohl, J., Colin Duncan, W., Rae, M. T., & Barlow, P. G. (2016). Ovine trophoblasts express cathelicidin host defence peptide in response to infection. Journal of Reproductive Immunology, 117, 10-16. https://doi.org/10.1016/j.jri.2016.06.006

Cationic host defence peptides (CHDP; also known as antimicrobial peptides) are key components of the immune response in the female reproductive tract. The role of the placental trophoblast in ovine host defence remains poorly understood. This study... Read More about Ovine trophoblasts express cathelicidin host defence peptide in response to infection.

Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs (2013)
Journal Article
Reid, J., Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. M. (2013). Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs. Journal of Small Animal Practice, 54(5), 227-233. https://doi.org/10.1111/jsap.12059

Objectives

To describe the development, preliminary validation and reliability testing of a shortened web-based form of GUVQuest, a structured questionnaire to measure health-related quality of life in dogs.
Methods

The original 109 items were... Read More about Development, validation and reliability of a web-based questionnaire to measure health-related quality of life in dogs.

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. M. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1). Animal Welfare, 20(4), 535=548

Health-related quality of life (HRQL) was defined for farmed animals and identified as an appropriate focus of integrative welfare
measurement for farmed pigs that embraces measurement of positive welfare. The instrument for HRQL measurement was
de... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (Part 1).

Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2) (2011)
Journal Article
Wiseman-Orr, M. L., Scott, E. M., & Nolan, A. (2011). Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2). Animal Welfare, 20(4), 549-558

The development of a novel structured questionnaire instrument to measure health-related quality of life (HRQL) in individual farmed pigs was described previously (companion paper). The instrument embraces the measurement of positive welfare, and was... Read More about Development and testing of a novel instrument to measure health-related quality of life (HRQL) of farmed pigs and promote welfare enhancement (part 2).

Quality of life is reduced in obese dogs but improves after successful weight loss (2011)
Journal Article
German, A. J., Holden, S. L., Wiseman-Orr, M. L., Reid, J., Nolan, A. M., Biourge, V., Morris, P. J., & Scott, E. M. (2012). Quality of life is reduced in obese dogs but improves after successful weight loss. Veterinary Journal, 192(3), 428-434. https://doi.org/10.1016/j.tvjl.2011.09.015

Obesity is thought to affect quality of life, but limited objective data exist to support this supposition. The current study aim was to use a questionnaire to determine health-related quality of life (HRQOL) both before and after weight loss, in obe... Read More about Quality of life is reduced in obese dogs but improves after successful weight loss.

The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs (2011)
Journal Article
Sandercock, D. A., Gibson, I. F., Rutherford, K. M. D., Donald, R. D., Lawrence, A. B., Brash, H. M., Scott, E. M., & Nolan, A. M. (2011). The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs. Physiology and Behavior, 104(5), 728-737. https://doi.org/10.1016/j.physbeh.2011.07.018

The consequences of tail-docking (at 2–4 days) and prenatal stress (maternal social stress during the 2nd third of pregnancy) on baseline nociceptive thresholds and responses to acute inflammatory challenge were investigated in juvenile pigs in two s... Read More about The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs.

Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood (2003)
Journal Article
Borwick, S., Rae, M., Brooks, J., McNeilly, A., Racey, P., & Rhind, S. (2003). Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood. Animal Reproduction Science, 77(1-2), 61-70. https://doi.org/10.1016/S0378-4320%2802%2900261-0

The effect of undernutrition in utero, during late gestation (from day 100), and early neonatal life on hypothalamic–pituitary function was investigated in female lambs born to ewes fed rations calculated to provide either 100% (high; H) or 70% (low;... Read More about Undernutrition of ewe lambs in utero and in early post-natal life does not affect hypothalamic–pituitary function in adulthood.

Non-genomic steroid receptors in the bovine ovary (2002)
Journal Article
Bramley, T., Menzies, G., Rae, M., & Scobie, G. (2002). Non-genomic steroid receptors in the bovine ovary. Domestic Animal Endocrinology, 23(1-2), 3-12. https://doi.org/10.1016/S0739-7240%2802%2900140-6

Over the last few years, rapid and physiologically important non-genomic actions of all classes of steroid hormones have been described in many cell types. A putative non-genomic membrane progesterone receptor (NGPR) was the first, and so far the onl... Read More about Non-genomic steroid receptors in the bovine ovary.

The effects of undernutrition, in utero, on reproductive function in adult male and female sheep (2002)
Journal Article
Rae, M., Kyle, C., Miller, D., Hammond, A., Brooks, A., & Rhind, S. (2002). The effects of undernutrition, in utero, on reproductive function in adult male and female sheep. Animal Reproduction Science, 72(1-2), 63-71. https://doi.org/10.1016/S0378-4320%2802%2900068-4

The aim of this study was to determine the effects of maternal undernutrition during pregnancy on adult reproductive function in male and female offspring. Groups of ewes were fed rations providing either 100% (High, H) or 50% (Low, L) of estimated m... Read More about The effects of undernutrition, in utero, on reproductive function in adult male and female sheep.

Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses (2001)
Journal Article
Rae, M., Palassio, S., Kyle, C., Brooks, A., Lea, R., Miller, D., & Rhind, S. (2001). Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses. Reproduction, 122, 915-922. https://doi.org/10.1530/rep.0.1220915

Gonad development in female sheep fetuses is thought to occur in a number of key stages. The aim of this study was to determine the effects of maternal undernutrition, applied at one or more of these critical stages, on fetal ovarian development. Gro... Read More about Effect of maternal undernutrition during pregnancy on early ovarian development and subsequent follicular development in sheep fetuses.

Stimulation of specific binding of [3H]-progesterone to bovine luteal cell-surface membranes: specificity of digitonin (1999)
Journal Article
Menzies, G., Howland, K., Rae, M., & Bramley, T. (1999). Stimulation of specific binding of [3H]-progesterone to bovine luteal cell-surface membranes: specificity of digitonin. Molecular and Cellular Endocrinology, 153, 57-69. https://doi.org/10.1016/S0303-7207%2899%2900091-X

Non-genomic actions of progesterone have been described in the ovary, and luteal membranes of several species have been shown to possess specific binding sites for [3H]-progesterone. However, binding of radiolabelled progesterone to luteal membranes... Read More about Stimulation of specific binding of [3H]-progesterone to bovine luteal cell-surface membranes: specificity of digitonin.

Bovine ovarian non-genomic progesterone binding sites: presence in follicular and luteal cell membranes (1998)
Journal Article
Rae, M., Menzies, G., & Bramley, T. (1998). Bovine ovarian non-genomic progesterone binding sites: presence in follicular and luteal cell membranes. Journal of Endocrinology, 159, 413-427. https://doi.org/10.1677/joe.0.1590413

We have shown recently that the bovine corpus luteum (CL) possesses specific luteal cell surface membrane binding sites for progesterone. We have now confirmed and extended these observations to compare the subcellular distribution of these binding s... Read More about Bovine ovarian non-genomic progesterone binding sites: presence in follicular and luteal cell membranes.

Specific Non-Genomic, Membrane-Localized Binding Sites for Progesterone in the Bovine Corpus Luteum1 (1998)
Journal Article
Rae, M. T., Menzies, G. S., McNeilly, A. S., Woad, K., Webb, R., & Bramley, T. A. (1998). Specific Non-Genomic, Membrane-Localized Binding Sites for Progesterone in the Bovine Corpus Luteum1. Biology of Reproduction, 58(6), 1394-1406. https://doi.org/10.1095/biolreprod58.6.1394

Fractionation of bovine corpus luteum (CL) homogenates on continuous sucrose density gradients with and without preincubation with 3H-progesterone demonstrated high levels of tracer binding and high content of endogenous progesterone associated with... Read More about Specific Non-Genomic, Membrane-Localized Binding Sites for Progesterone in the Bovine Corpus Luteum1.

External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment (1993)
Journal Article
Proudfoot, L., Kusel, J. R., Smith, H. V., & Kennedy, M. W. (1993). External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment. Parasitology, 107(05), 559. https://doi.org/10.1017/s0031182000068141

Previous work has shown that the surface of infective larvae of parasitic nematodes will not bind the fluorescent lipid analogue 5-N(octadecanoyl)aminofluorescein (AF18) until after exposure of the parasite to mammalian tissue-culture conditions. In... Read More about External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment.