The Effects of Inflammatory Bowel Disease Drugs on the Autophagy Pathway (2019)
Thesis
Hooper, K. The Effects of Inflammatory Bowel Disease Drugs on the Autophagy Pathway. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/2070992

Crohn’s disease (CD), one of the main forms of Inflammatory Bowel Disease (IBD), is a complex disorder characterised by chronic inflammation of the gastrointestinal (GI) tract. The aetiology of CD involves genetics and environmental factors that trig... Read More about The Effects of Inflammatory Bowel Disease Drugs on the Autophagy Pathway.

The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK (2019)
Journal Article
Hooper, K. M., Casanova, V., Kemp, S., Staines, K. A., Satsangi, J., Barlow, P. G., Henderson, P., & Stevens, C. (2019). The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK. Inflammatory Bowel Diseases, 25(9), 1481-1496. https://doi.org/10.1093/ibd/izz039

Background Genetic studies have strongly linked autophagy to Crohn's disease (CD) and stimulating autophagy in CD patients may be therapeutically beneficial. The aim of this study was to evaluate the effect of current inflammatory bowel disease (IBD)... Read More about The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK.