The role of the human cathelicidin LL-37 in rhinovirus infection (2019)
Thesis
Henderson Sousa, F. The role of the human cathelicidin LL-37 in rhinovirus infection. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/2070903

Human rhinoviruses (HRVs) are the most common causes for symptomatic respiratory infections, and have been linked to severe respiratory conditions in children, and in immunocompromised and elderly individuals. Currently there are no specific treatmen... Read More about The role of the human cathelicidin LL-37 in rhinovirus infection.

Mobile technology utilization among patients from diverse cultural and linguistic backgrounds attending cardiac rehabilitation. (2018)
Journal Article
Zhang, L., Ding, D., Neubeck, L., Gallagher, P., Paull, G., Gao, Y., & Gallagher, R. (2018). Mobile technology utilization among patients from diverse cultural and linguistic backgrounds attending cardiac rehabilitation. JMIR Cardio, 2(1), Article e13. https://doi.org/10.2196/cardio.9424

Background: Barriers to attending cardiac rehabilitation (CR), including cultural and linguistic differences, may be addressed
by recent technological developments. However, the feasibility of using these approaches in culturally and linguistically... Read More about Mobile technology utilization among patients from diverse cultural and linguistic backgrounds attending cardiac rehabilitation..

Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study (2018)
Journal Article
Lone, N. I., Lee, R., Salisbury, L., Donaghy, E., Ramsay, P., Rattray, J., & Walsh, T. S. (2019). Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study. Thorax, 75(11), 1046-1054. https://doi.org/10.1136/thoraxjnl-2017-210822

Background
Intensive care unit survivors experience high levels of morbidity after hospital discharge and are at high risk of unplanned hospital readmission. Identifying those at highest-risk before hospital discharge may allow targeting of novel ri... Read More about Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study.

A physical activity referral program improves risk factors in those who have completed cardiac rehabilitation. (2017)
Presentation / Conference Contribution
Hanson, C., Neubeck, L., & Dodd-Reynolds, C. (2017, August). A physical activity referral program improves risk factors in those who have completed cardiac rehabilitation. Presented at 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, Perth, Australia

Background: On completion of cardiac rehabilitation (CR), participants may be referred to community-based physical activity programs. There is limited data to determine additional benefits of these programs supplemental to CR.

Methods: Using longi... Read More about A physical activity referral program improves risk factors in those who have completed cardiac rehabilitation..

Achieving Good Outcomes for Asthma Living (GOAL): Mixed methods feasibility and pilot cluster randomised controlled trial of a practical intervention for eliciting, setting and achieving goals for adults with asthma (2016)
Journal Article
Hoskins, G., Williams, B., Abhyankar, P., Donnan, P., Duncan, E., Pinnock, H., Pol, M., Rauchhaus, P., Taylor, A., & Sheikh, A. (2016). Achieving Good Outcomes for Asthma Living (GOAL): Mixed methods feasibility and pilot cluster randomised controlled trial of a practical intervention for eliciting, setting and achieving goals for adults with asthma. Trials, 17(1), Article 584. https://doi.org/10.1186/s13063-016-1684-7

Background
Despite being a core component of self-management, goal setting is rarely used in routine care. We piloted a primary care, nurse-led intervention called Achieving Good Outcomes for Asthma Living (GOAL) for adults with asthma. Patients wer... Read More about Achieving Good Outcomes for Asthma Living (GOAL): Mixed methods feasibility and pilot cluster randomised controlled trial of a practical intervention for eliciting, setting and achieving goals for adults with asthma.

A theory-informed approach to developing visually mediated interventions to change behaviour using an asthma and physical activity intervention exemplar (2016)
Journal Article
Murray, J., Williams, B., Hoskins, G., Skar, S., McGhee, J., Treweek, S., Sniehotta, F. F., Sheikh, A., Brown, G., Hagen, S., Cameron, L., Jones, C., & Gauld, D. (2016). A theory-informed approach to developing visually mediated interventions to change behaviour using an asthma and physical activity intervention exemplar. Pilot and Feasibility Studies, 2, Article 46. https://doi.org/10.1186/s40814-016-0091-x

Background Visualisation techniques are used in a range of healthcare interventions. However, these frequently lack a coherent rationale or clear theoretical basis. This lack of definition and explicit targeting of the underlying mechanisms may impe... Read More about A theory-informed approach to developing visually mediated interventions to change behaviour using an asthma and physical activity intervention exemplar.

The ‘vicious cycle’ of personalised asthma action plan implementation in primary care: a qualitative study of patients and health professionals’ views (2015)
Journal Article
Ring, N., Booth, H., Wilson, C., Hoskins, G., Pinnock, H., Sheikh, A., & Jepson, R. (2015). The ‘vicious cycle’ of personalised asthma action plan implementation in primary care: a qualitative study of patients and health professionals’ views. BMC Family Practice, 16(1), https://doi.org/10.1186/s12875-015-0352-4

Background: Personal asthma action plans (PAAPs) have been guideline recommended for years, but consistently
under-issued by health professionals and under-utilised by patients. Previous studies have investigated sub-optimal
PAAP implementation but... Read More about The ‘vicious cycle’ of personalised asthma action plan implementation in primary care: a qualitative study of patients and health professionals’ views.

P109 Can A Theory-informed Interactive Animation Increase Intentions To Engage In Physical Activity In Young People With Asthma? (2014)
Journal Article
Hoskins, G., Williams, B. W., Murray, J., Skar, S., McGhee, J., Gauld, D., Brown, G., Treweek, S., Sniehotta, F., Cameron, L., Sheikh, A., & Hagen, S. (2014). P109 Can A Theory-informed Interactive Animation Increase Intentions To Engage In Physical Activity In Young People With Asthma?. Thorax, 69(Suppl 2), A125-A125. https://doi.org/10.1136/thoraxjnl-2014-206260.250

Background Participation in regular physical activity improves aerobic fitness and well-being. For people with asthma the benefits also include reduced hospital admissions, absenteeism, medication use, and improved ability to cope with the disease. H... Read More about P109 Can A Theory-informed Interactive Animation Increase Intentions To Engage In Physical Activity In Young People With Asthma?.

Lung Inflammation, oxidative stress and air pollution. (2014)
Book Chapter
Gomes, E. C., & Florida-James, G. (2014). Lung Inflammation, oxidative stress and air pollution. In K. C. Ong (Ed.), Lung Inflammation. InTech. https://doi.org/10.5772/58252

This is a very relevant chapter in the context of “Lung Inflammation” because it details and discusses an important theme in this area: air pollution. The analyses of epidemiological studies, conducted in various urban centres, have provided coherent... Read More about Lung Inflammation, oxidative stress and air pollution..

Left in the dark about asthma: Older asthma patients are often unaware of their potentially fatal condition and how to manage it effectively until a severe attack strikes, say Elaine Carnegie and Angela Jones (2013)
Journal Article
Carnegie, E., & Jones, A. (2013). Left in the dark about asthma: Older asthma patients are often unaware of their potentially fatal condition and how to manage it effectively until a severe attack strikes, say Elaine Carnegie and Angela Jones. Nursing Older People, 25(9), 11-11. https://doi.org/10.7748/nop2013.11.25.9.11.s14

THE PREVALENCE of asthma in older people in developed countries has been estimated at between 6 and 10 per cent of the population (Cardona et al 2011). The proportion of the overall number of asthma deaths in the over-65s remains high – 75 per cent;... Read More about Left in the dark about asthma: Older asthma patients are often unaware of their potentially fatal condition and how to manage it effectively until a severe attack strikes, say Elaine Carnegie and Angela Jones.

Improving the management of asthma in older adults (2013)
Journal Article
Carnegie, E., & Jones, A. (2013). Improving the management of asthma in older adults. Nursing Standard, 28(13), 50-58. https://doi.org/10.7748/ns2013.11.28.13.50.e8075

Older people with asthma are a discrete patient group that requires specialist nursing skills and knowledge. They have specific and sometimes hidden needs that will affect their quality of life unless these are addressed by caring and competent nurse... Read More about Improving the management of asthma in older adults.

Goal-setting intervention in patients with active asthma: Protocol for a pilot cluster-randomised controlled trial (2013)
Journal Article
Hoskins, G., Abhyankar, P., Taylor, A. D., Duncan, E., Sheikh, A., Pinnock, H., van der Pol, M., Donnan, P. T., & Williams, B. (2013). Goal-setting intervention in patients with active asthma: Protocol for a pilot cluster-randomised controlled trial. Trials, 14, Article 289. https://doi.org/10.1186/1745-6215-14-289

Background: Supporting self-management behaviours is recommended guidance for people with asthma. Preliminary work suggests that a brief, intensive, patient-centred intervention may be successful in supporting people with asthma to participate in lif... Read More about Goal-setting intervention in patients with active asthma: Protocol for a pilot cluster-randomised controlled trial.

Developing novel evidence-based interventions to promote asthma action plan use: a cross-study synthesis of evidence from randomised controlled trials and qualitative studies (2012)
Journal Article
Ring, N., Jepson, R., Pinnock, H., Wilson, C., Hoskins, G., Wyke, S., & Sheikh, A. (2012). Developing novel evidence-based interventions to promote asthma action plan use: a cross-study synthesis of evidence from randomised controlled trials and qualitative studies. Trials, 13(1), https://doi.org/10.1186/1745-6215-13-216

Background: Long-standing randomised controlled trial (RCT) evidence indicates that asthma action plans can improve patient outcomes. Internationally, however, these plans are seldom issued by professionals or used by patients/carers. To understand h... Read More about Developing novel evidence-based interventions to promote asthma action plan use: a cross-study synthesis of evidence from randomised controlled trials and qualitative studies.

Patient, practice and organisational influences on asthma control: Observational data from a national study on primary care in the United Kingdom (2011)
Journal Article
Hoskins, G., Williams, B., Jackson, C., Norman, P., & Donnan, P. (2012). Patient, practice and organisational influences on asthma control: Observational data from a national study on primary care in the United Kingdom. International Journal of Nursing Studies, 49(5), 596-609. https://doi.org/10.1016/j.ijnurstu.2011.10.017

Background: Achieving asthma control is central to optimising patient quality of life and clinical outcome. Contemporary models of chronic disease management across a variety of countries point to the importance of micro, meso and macro level influen... Read More about Patient, practice and organisational influences on asthma control: Observational data from a national study on primary care in the United Kingdom.

Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37 (2011)
Journal Article
Barlow, P. G., Svoboda, P., Mackellar, A., Nash, A. A., York, I. A., Pohl, J., Davidson, D. J., & Donis, R. O. (2011). Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37. PLOS ONE, 6(10), Article e25333. https://doi.org/10.1371/journal.pone.0025333

The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches. Cationic Host Defense Peptides (CHDP, also known as antimicrobial peptid... Read More about Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37.

Understanding what asthma plans mean: a linguistic analysis of terminology used in published texts (2011)
Journal Article
Ring, N., Pinnock, H., Wilson, C., Hoskins, G., Jepson, R., Wyke, S., & Sheikh, A. (2011). Understanding what asthma plans mean: a linguistic analysis of terminology used in published texts. Primary Care Respiratory Journal, 20(2), 170-177. https://doi.org/10.4104/pcrj.2011.00012

Aim: To identify from the literature what terms are used for ‘asthma plans’, with what meaning, and in what context(s).
Methods: Linguistic analysis of a selected body of asthma literature from 1989-2009.
Results: A wide range of asthma plan termin... Read More about Understanding what asthma plans mean: a linguistic analysis of terminology used in published texts.

Tacit and transitionary: An exploration of patients’ and primary care health professionals’ goals in relation to asthma (2011)
Journal Article
Williams, B., Steven, K., & Sullivan, F. M. (2011). Tacit and transitionary: An exploration of patients’ and primary care health professionals’ goals in relation to asthma. Social Science and Medicine, 72(8), 1359-1366. https://doi.org/10.1016/j.socscimed.2011.02.038

Goal setting is recommended in UK health policy to make health care more patient-centred, to enhance the likelihood of behaviour change and to improve health outcomes. Patient-centred care is thought to be particularly important in the management of... Read More about Tacit and transitionary: An exploration of patients’ and primary care health professionals’ goals in relation to asthma.

Understanding what helps or hinders asthma action plan use: A systematic review and synthesis of the qualitative literature (2011)
Journal Article
Ring, N., Jepson, R., Hoskins, G., Wilson, C., Pinnock, H., Sheikh, A., & Wyke, S. (2011). Understanding what helps or hinders asthma action plan use: A systematic review and synthesis of the qualitative literature. Patient Education and Counseling, 85(2), e131-e143. https://doi.org/10.1016/j.pec.2011.01.025

Objective: To understand better what helps and/or hinders asthma action plan use from the professionals and patients/carers perspective.
Methods: Systematic review and qualitative synthesis (using meta-ethnography).
Results: Nineteen studies (20 pa... Read More about Understanding what helps or hinders asthma action plan use: A systematic review and synthesis of the qualitative literature.

Recent temporal changes in lipid management and serum cholesterol after acute coronary syndromes. (2011)
Journal Article
Neubeck, L., Redfern, J., Briffa, T., Bauman, A., & Freedman, S. (2011). Recent temporal changes in lipid management and serum cholesterol after acute coronary syndromes. Heart, Lung and Circulation, 20(2), S249. https://doi.org/10.1016/j.hlc.2011.05.611

Lipid lowering is of paramount importance in the prevention of recurrent cardiovascular events. Our original CHOICE (Choice of Health Options In prevention of Cardiovascular Events) trial demonstrated significant benefit in lowering total cholesterol... Read More about Recent temporal changes in lipid management and serum cholesterol after acute coronary syndromes..

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium (2010)
Journal Article
Barlow, P. G., Beaumont, P. E., Cosseau, C., Mackellar, A., Wilkinson, T. S., Hancock, R. E. W., Haslett, C., Govan, J. R. W., Simpson, A. J., & Davidson, D. J. (2010). The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium. American Journal of Respiratory Cell and Molecular Biology, 43(6), 692-702. https://doi.org/10.1165/rcmb.2009-0250oc

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human... Read More about The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium.