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Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety (2019)
Journal Article
Morgenroth, E., Orlov, N., Lythgoe, D. J., Stone, J. M., Barker, H., Munro, J., Eysenck, M., & Allen, P. (2019). Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety. Cortex, 117, 53-63. https://doi.org/10.1016/j.cortex.2019.02.021

Trait anxiety can affect cognitive control resulting in ineffective and/or inefficient task performance. Moreover, previous functional Magnetic Resonance Imaging (fMRI) studies have reported altered dorsolateral prefrontal cortex (DLPFC) activity in... Read More about Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety.

Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population (2018)
Journal Article
Carmichael, D. A., Smees, R., Shillcock, R. C., & Simner, J. (2019). Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population. British Journal of Psychology, 110(3), 530-548. https://doi.org/10.1111/bjop.12354

Synaesthesia has long been considered a benign alternative form of perception most often associated with positive rather than negative outcomes. The condition has been associated with a variety of cognitive and perceptual advantages, including benefi... Read More about Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population.

Developing guidance to inform a clinically meaningful and feasible suicide risk assessment measure for use in emergency departments (2018)
Thesis
McClatchey, K. Developing guidance to inform a clinically meaningful and feasible suicide risk assessment measure for use in emergency departments. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/1256366

Introduction: Over 800,000 people die by suicide each year, and despite being a global public health issue, limited research exists exploring suicide risk assessment practices in emergency departments. The current thesis investigated emergency depart... Read More about Developing guidance to inform a clinically meaningful and feasible suicide risk assessment measure for use in emergency departments.

Power and research: a qualitative approach to understanding the relationship between major mental illness, masculinity and violence (2018)
Digital Artefact
Haddow, C. (2018). Power and research: a qualitative approach to understanding the relationship between major mental illness, masculinity and violence. [Sage Research Methods Case Study]

This case study reflects on research which explored the relationship between major mental illness and masculinity in the context of violent offending behavior. Studies which examine violence by the mentally disordered largely look to mental illness a... Read More about Power and research: a qualitative approach to understanding the relationship between major mental illness, masculinity and violence.

Promoting student well-being: Are you better than you think? (2017)
Journal Article
Robertson, P. (2017). Promoting student well-being: Are you better than you think?. Phoenix (AGCAS journal), 20-21

Dr Pete Robertson, Associate Professor & Programme Leader for Career Guidance in the School of Applied Sciences at Edinburgh Napier University, outlines proactive approaches that careers services can adopt to respond to the challenges of supporting s... Read More about Promoting student well-being: Are you better than you think?.

A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial (2015)
Journal Article
Pomeroy, V. M., Rowe, P., Clark, A., Walker, A., Kerr, A., Chandler, E., Barber, M., Baron, J., Anderson, L., Dounavi, M., Earl, L., Gregory, S., Havis, C., Horton, S., Jones, P. S., Kaliarntas, K., Kennedy, N., Lane, K., Legg, D., Marrapu, S. T., …Ugboule, U. C. (2016). A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial. Neurorehabilitation and Neural Repair, 30(1), 40-48. https://doi.org/10.1177/1545968315583724

Background. Timely provision of an ankle-foot orthosis (AFO) orthotist customized for individuals early after stroke can be problematic. Objective. To evaluate the efficacy of a therapist-made AFO (SWIFT Cast) for walking recovery.
Methods.
This w... Read More about A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial.

Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review (2014)
Journal Article
Graham, S. M., Baird, M., & Boyd, G. W. (2014). Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease, 4(3), 286-298. https://doi.org/10.5628/aehd.v4i3.169

Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic neurons in
the substantia nigra region of the brain. Symptoms and signs m... Read More about Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review.

Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development (2014)
Journal Article
Girardi, G., Fraser, J., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015). Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. Molecular Psychiatry, 20(8), 1017-1026. https://doi.org/10.1038/mp.2014.110

In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of
complement activation in placenta and foetal brain in vivo in utero. Using this method, we found that anti-complement
C3-targeted ultras... Read More about Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development.

"I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis. (2013)
Journal Article
Welsh, P., & Brown, S. (2013). "I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis. Health, Risk and Society, 15, 648-662. https://doi.org/10.1080/13698575.2013.848846

In this article we examine the identification of young people deemed to be at an elevated risk of developing psychosis (often referred to as an At-Risk Mental State for psychosis). Although this is not a new concept within psychiatry, there has been... Read More about "I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis..

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease (2009)
Journal Article
Kerr, F., Augustin, H., Piper, M. D. W., Gandy, C., Allen, M. J., Lovestone, S., & Partridge, L. (2011). Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging, 32(11), 1977-1989. https://doi.org/10.1016/j.neurobiolaging.2009.10.015

Dietary restriction (DR) extends lifespan in diverse organisms and, in animal and cellular models, can delay a range of aging-related diseases including Alzheimer's disease (AD). A better understanding of the mechanisms mediating these interactions,... Read More about Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease.

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease (2004)
Journal Article
Hye, A., Kerr, F., Archer, N., Foy, C., Poppe, M., Brown, R., …Lovestone, S. (2004). Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters, 373(1), 1-4. https://doi.org/10.1016/j.neulet.2004.10.031

Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease modifying treatment. As increasing evidence has suggested a role for glycogen synthase kinase-3 (GSK-3) in the pathogenesis of the condition we measu... Read More about Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease.

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5 (1996)
Journal Article
Sander, T., Hildmann, T., Janz, D., Wienker, T. F., Bianchi, A., Bauer, G., Sailer, U., Scaramelli, A., Neitzel, H., Schmitz, B., Bailey, M. E., Beck-Mannagetta, G., Johnson, K. J., & Darlison, M. G. (1996). Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5. Epilepsy Research, 23(3), 235-244. https://doi.org/10.1016/0920-1211%2895%2900098-4

Hereditary factors play a major role in the etiology of idiopathic generalized epilepsies (IGEs). The pivotal function of ionotropic γ-aminobutyric acid type A receptors (GABRs) in inhibitory neurotransmission in the mammalian central nervous system... Read More about Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5.

Schizophrenia and GABAA receptor subunit genes (1995)
Journal Article
Byerley, W., Bailey, M. E., Hicks, A. A., Riley, B. P., Darlison, M. G., Holik, J., …Coon, H. (1995). Schizophrenia and GABAA receptor subunit genes. Psychiatric Genetics, 5(1), 23-30. https://doi.org/10.1097/00041444-199521000-00004

Alterations in γ-aminobutyric acid (GABA) neurotransmission have been indirectly implicated in the pathogenesis of schizophrenia. Using nine multiplex pedigrees, we tested for linkage between schizophrenia and simple sequence repeat polymorphisms for... Read More about Schizophrenia and GABAA receptor subunit genes.

GABAAreceptor subtypes: which, where and why? (1995)
Journal Article
Darlison, M. G., & Albrecht, B. E. (1995). GABAAreceptor subtypes: which, where and why?. Seminars in the neurosciences, 7(2), 115-126. https://doi.org/10.1006/smns.1995.0013

Synaptic inhibition in the vertebrate central nervous system is mediated predominantly by subtypes of the GABAAreceptor, which comprise different pentameric combinations of the products of 13 genes. In this article, we review the results of recent ex... Read More about GABAAreceptor subtypes: which, where and why?.

Isolation and sequence analysis of the chicken GABAa receptor α1-subunit gene promoter (1995)
Journal Article
Bateson, A. N., Ultsch, A., & Darlison, M. G. (1995). Isolation and sequence analysis of the chicken GABAa receptor α1-subunit gene promoter. Gene, 153(2), 243-247. https://doi.org/10.1016/0378-1119%2894%2900776-o

A genomic clone containing the 5'-flanking sequence of the chicken {GABAA} receptor α1-subunit-encoding gene (GabRα1) was isolated and characterized. An intron was found to interrupt the 5'-untranslated region. The transcription start point (tsp) was... Read More about Isolation and sequence analysis of the chicken GABAa receptor α1-subunit gene promoter.

A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia. (1991)
Thesis
Crerar, M. A. A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/4968

This thesis investigates impairments of written sentence comprehension in 14
aphasic adults. The primary purpose of the research was to apply computer
technology to the process of assessment, with the aim of improving diagnostic
precision and ther... Read More about A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia..