UKCP: a collaborative network of cerebral palsy registers in the United Kingdom. (2006)
Journal Article
Bonellie, S., Colver, A., Surman, G., Chalmers, J., Dolk, H., Hemming, K., King, A., Kurinczuk, J. J., Parkes, J., & Platt, M. J. (2006). UKCP: a collaborative network of cerebral palsy registers in the United Kingdom. Journal of Public Health, 28, 148-156. https://doi.org/10.1093/pubmed/fdi087

Cerebral palsy (CP) is a relatively rare condition with enormous social and financial impact. Information about CP is not routinely collected in the United Kingdom. We have pooled non-identifiable data from the five currently active UK CP registers t... Read More about UKCP: a collaborative network of cerebral palsy registers in the United Kingdom..

Exploring the role of community palliative care nurse specialists as educators. (2006)
Journal Article
Husband, J., & Kennedy, C. (2006). Exploring the role of community palliative care nurse specialists as educators. International Journal of Palliative Nursing, 12, 277-284

In the UK the clinical nurse specialist role (CNS) has evolved in an uncoordinated manner resulting in a broad job remit, with clinical, managerial, research and educational elements. CNSs working in specialist palliative care are expected to contrib... Read More about Exploring the role of community palliative care nurse specialists as educators..

A pilot study of brain tumour growth between radiotherapy planning and delivery. (2006)
Journal Article
Pennington, C., Kilbride, L., Grant, R., & Wardlaw, J. M. (2006). A pilot study of brain tumour growth between radiotherapy planning and delivery. Clinical Oncology, 18(2), 104-108. https://doi.org/10.1016/j.clon.2005.09.004

Aims
Delays between surgery and the delivery of radiotherapy may allow brain tumours to grow beyond the planned radiotherapy fields and therefore reduce the effectiveness of radiotherapy. This pilot study aimed to ascertain whether significant growt... Read More about A pilot study of brain tumour growth between radiotherapy planning and delivery..

Assessment of health-related quality of life in patients with lymphedema of the lower limb (2006)
Journal Article
Franks, P. J., Moffatt, C. J., Doherty, D. C., Williams, A. F., Jeffs, E., & Mortimer, P. S. (2006). Assessment of health-related quality of life in patients with lymphedema of the lower limb. Wound Repair and Regeneration, 14(2), 110-118. https://doi.org/10.1111/j.1743-6109.2006.00099.x

The purpose of this study was to examine the use of a number of tools in the evaluation of health-related quality of life in patients with lower limb lymphedema, and to determine the consequences of cancer history and concurrent leg ulceration. Patie... Read More about Assessment of health-related quality of life in patients with lymphedema of the lower limb.

Central periodic breathing observed on hospital admission is associated with an adverse prognosis in conscious acute stroke patients (2006)
Journal Article
Rowat, A. M., Dennis, M. S., & Wardlaw, J. M. (2006). Central periodic breathing observed on hospital admission is associated with an adverse prognosis in conscious acute stroke patients. Cerebrovascular Diseases, 21, 340-347. https://doi.org/10.1159/000091540

Background: Central periodic breathing (CPB) is common following acute stroke, but its prognostic significance is uncertain. We determined the frequency of CPB on admission with stroke and assessed whether it was related to outcome. Methods: We measu... Read More about Central periodic breathing observed on hospital admission is associated with an adverse prognosis in conscious acute stroke patients.

Hypoxaemia in acute stroke is frequent and worsens outcome. (2006)
Journal Article
Rowat, A. M., Dennis, M. S., & Wardlaw, J. M. (2006). Hypoxaemia in acute stroke is frequent and worsens outcome. Cerebrovascular Diseases, 21, 166-172. https://doi.org/10.1159/000090528

Background: Hypoxaemia in the acute phase of stroke might damage the ischaemic penumbra and worsen clinical outcome. We determined the frequency of hypoxaemia on admission with stroke and assessed whether it was related to outcome. Methods: We measur... Read More about Hypoxaemia in acute stroke is frequent and worsens outcome..

Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. (2005)
Journal Article
Barlow, P. G., Clouter-Baker, A., Donaldson, K., MacCallum, J., & Stone, V. (2005). Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Particle and fibre toxicology, 2(1), 11-24. https://doi.org/10.1186/1743-8977-2-11

Background - Alveolar macrophages are a key cell in dealing with particles deposited in the lungs and in determining the subsequent response to that particle exposure. Nanoparticles are considered a potential threat to the lungs and the mechanism of... Read More about Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages..

Comparison of risk factors for cerebral palsy in twins and singletons. (2005)
Journal Article
Bonellie, S., Currie, D., & Chalmers, J. (2005). Comparison of risk factors for cerebral palsy in twins and singletons. Developmental Medicine and Child Neurology, 47, 587-591. https://doi.org/10.1017/S0012162205001167

The aim of this study was to investigate the difference in rates of cerebral palsy (CP) between singletons and twins by considering factors that may be predictive of CP. Data were taken from the Scottish Register of Children with a Motor Deficit of C... Read More about Comparison of risk factors for cerebral palsy in twins and singletons..

Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns. (2005)
Journal Article
Williams, K. R., NaWishart, J. G., Pitcairn, T. K., & Willis, D. (2005). Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns. American journal of mental retardation : AJMR, 110, 387-392

The ability of children with Down syndrome to recognize expressions of emotion was compared to performance in typically developing and nonspecific intellectual disability groups matched on either MA or a performance-related measure. Our goal was to (... Read More about Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns..

Hippocalcin functions as a calcium sensor in hippocampal LTD (2005)
Journal Article
Palmer, C., Lim, W., Hastie, P. G. R., Toward, M., Korolchuk, V. I., Burbidge, S. A., Banting, G., Collingridge, G. L., Isaac, J. T. R., & Henley, J. M. (2005). Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron, 47(4), 487-494. https://doi.org/10.1016/j.neuron.2005.06.014

It is not fully understood how NMDAR-dependent LTD causes Ca2+-dependent endocytosis of AMPARs. Here we show that the neuronal Ca2+ sensor hippocalcin binds the β2-adaptin subunit of the AP2 adaptor complex and that along with GluR2 these coimmunopre... Read More about Hippocalcin functions as a calcium sensor in hippocampal LTD.

Wavelet analysis of the ECG: A review (2005)
Journal Article
Addison, P. (2005). Wavelet analysis of the ECG: A review. Physiological Measurement, 26(5), 155-199. https://doi.org/10.1088/0967-3334/26/5/R01

The wavelet transform has emerged over recent years as a powerful time–frequency analysis and signal coding tool favoured for the interrogation of complex nonstationary signals. Its application to biosignal processing has been at the forefront of the... Read More about Wavelet analysis of the ECG: A review.

Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. (2005)
Journal Article
Dias, N., Goossens, J.-F., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., Bernal, J., Turnbull, A., Mincher, D., & Bailly, C. (2005). Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. Bioconjugate Chemistry, 16(4), 949-958. https://doi.org/10.1021/bc050065x

We report the synthesis of an original series of oxoazabenzo[de]anthracenes conjugated to an amino acid: Ala, Phe, Pro, Lys, or Gly (4a-e, respectively). The compounds, derived from 1,8-dihydroxyanthracene-9,10-dione, were studied for DNA binding and... Read More about Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents..

Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model (2005)
Journal Article
Van Valckenborgh, E., Mincher, D., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., & Vanderkerken, K. (2005). Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model. Leukemia, 19(9), 1628-1633. https://doi.org/10.1038/sj.leu.2403866

Multiple myeloma (MM) is an incurable B-cell cancer characterised by the monoclonal proliferation of tumour cells in the bone marrow (BM). It has been described that matrix metalloproteinases (MMPs) and especially MMP-9 is secreted by MM cells. In th... Read More about Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model.

Gastrointestinal Nursing (2005)
Book
Smith, G. D., & Watson, R. (2005). Gastrointestinal Nursing. Wiley. https://doi.org/10.1002/9780470774359

Many nurses work as specialist practitioners within several areas of gastrointestinal medicine, including inflammatory bowel disease, stoma care, nutrition, endoscopy and counselling. There has been a steady increase in nurse-led services and gastroi... Read More about Gastrointestinal Nursing.

Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver (2005)
Journal Article
Wheelhouse, N. M., Lai, P. B. S., Wigmore, S. J., Ross, J. A., & Harrison, D. J. (2005). Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver. British Journal of Cancer, 92(7), 1268-1272. https://doi.org/10.1038/sj.bjc.6602496

The largest single underlying cause of hepatocellular carcinoma (HCC) worldwide is hepatitis B virus (HBV) infection. Hepatitis B virus increases cellular oxidative stress and the development of HCC occurs after a long latency period. The study was c... Read More about Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver.

Heart rate variability measurements and the prediction of ventricular arrhythmias. (2005)
Journal Article
Reed, M. J., Addison, P., & Robertson, C. E. (2005). Heart rate variability measurements and the prediction of ventricular arrhythmias. QJM: An International Journal of Medicine, 98, 87-95. https://doi.org/10.1093/qjmed/hci018

Heart rate variability (HRV) is the temporal variation
between sequences of consecutive heartbeats. It is possible that HRV confers a survival advantage.In normal subjects, a variable heart rate is the normal physiological state. A loss of variabili... Read More about Heart rate variability measurements and the prediction of ventricular arrhythmias..

Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties (2005)
Journal Article
Hand, P. J., Wardlaw, J. M., Rowat, A. M., Haisma, J. A., Lindley, R. I., & Dennis, M. S. (2005). Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties. Journal of Neurology, Neurosurgery and Psychiatry, 76, 1525-1527. https://doi.org/10.1136/jnnp.2005.062539

Objectives: To assess organisational and patient specific limitations and safety of magnetic resonance
imaging (MRI) as the first line investigation for hospital admitted stroke patients.
Methods: Consecutive patients admitted with acute stroke wer... Read More about Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties.

The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. (2005)
Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005). The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7

-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synaptic transmission, and their overactivation is potently excitotoxic. Recent fi... Read More about The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors..

Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature. (2004)
Journal Article
Chouliara, Z. (2004). Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature. Annals of Oncology, 15, 1596-1602. https://doi.org/10.1093/annonc/mdh423

Background: Several studies have identified inadequacies in the care and treatment received by older patients with cancer, as opposed to their younger counterparts. These include over or under diagnosis, ineffective symptom management and lower survi... Read More about Perceptions of older people with cancer of information, decision making and treatment: a systematic review of selected literature..

Improved prediction of defibrillation success for out-of-hospital VF cardiac arrest using wavelet transform methods (2004)
Journal Article
Watson, J. N., Uchaipichata, N., Addison, P., Clegg, G. R., Robertson, C. E., Eftestol, T., & Steen, P. A. (2004). Improved prediction of defibrillation success for out-of-hospital VF cardiac arrest using wavelet transform methods. Resuscitation, 63(3), 269-275. https://doi.org/10.1016/j.resuscitation.2004.06.012

We report an improved method for the estimation of shock outcome prediction based on novel wavelet transform-based time-frequency methods. Wavelet-based peak frequency, energy, mean frequency, spectral flatness and a new entropy measure were studied... Read More about Improved prediction of defibrillation success for out-of-hospital VF cardiac arrest using wavelet transform methods.