Effectiveness of Online Cancer Education for Nurses and Allied Health Professionals; a Systematic Review Using Kirkpatrick Evaluation Framework (2017)
Journal Article
Campbell, K., Taylor, V., & Douglas, S. (2017). Effectiveness of Online Cancer Education for Nurses and Allied Health Professionals; a Systematic Review Using Kirkpatrick Evaluation Framework. Journal of Cancer Education, https://doi.org/10.1007/s13187-017-1308-2

Embedding online learning within higher education can provide engaging, cost-effective, interactive and flexible education. By evaluating the impact, outcomes and pedagogical influence of online cancer and education, future curricula can be shaped an... Read More about Effectiveness of Online Cancer Education for Nurses and Allied Health Professionals; a Systematic Review Using Kirkpatrick Evaluation Framework.

Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation (2017)
Journal Article
Monahan, M., Jowett, S., Lovibond, K., Gill, P., Godwin, M., Greenfield, S., Hanley, J., Hobbs, F. R., Martin, U., Mant, J., McKinstry, B., Williams, B., Sheppard, J. P., & McManus, R. J. (2017). Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation. Hypertension, https://doi.org/10.1161/hypertensionaha.117.10244

Clinical guidelines in the United States and United Kingdom recommend that individuals with suspected hypertension should have ambulatory blood pressure (BP) monitoring to confirm the diagnosis. This approach reduces misdiagnosis because of white coa... Read More about Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation.

Lack of concordance between ECDC and CDC systems for surveillance of ventilator associated pneumonia (2017)
Journal Article
Craven, T. H., Wojcik, G., McCoubrey, J., Brooks, O., Grant, E., Reilly, J., Laurenson, I. F., Kefala, K., & Walsh, T. S. (2018). Lack of concordance between ECDC and CDC systems for surveillance of ventilator associated pneumonia. Intensive Care Medicine, https://doi.org/10.1007/s00134-017-4993-8

no abstract available.

The online version of this article (https://doi.org/10.1007/s00134-017-4993-8) contains supplementary material, which is available to authorized users.

Engineering Specificity and Function of Therapeutic Regulatory T Cells (2017)
Journal Article
McGovern, J. L., Wright, G. P., & Stauss, H. J. (2017). Engineering Specificity and Function of Therapeutic Regulatory T Cells. Frontiers in Immunology, 8, Article 1517. https://doi.org/10.3389/fimmu.2017.01517

Adoptive therapy with polyclonal regulatory T cells (Tregs) has shown efficacy in suppressing detrimental immune responses in experimental models of autoimmunity and transplantation. The lack of specificity is a potential limitation of Treg therapy,... Read More about Engineering Specificity and Function of Therapeutic Regulatory T Cells.

Control of Antimicrobial Resistance Requires an Ethical Approach (2017)
Journal Article
Parsonage, B., Hagglund, P. K., Keogh, L., Wheelhouse, N., Brown, R. E., & Dancer, S. J. (2017). Control of Antimicrobial Resistance Requires an Ethical Approach. Frontiers in Microbiology, 8, https://doi.org/10.3389/fmicb.2017.02124

Ethical behavior encompasses actions that benefit both self and society. This means that tackling antimicrobial resistance (AMR) becomes an ethical obligation, because the prospect of declining anti-infectives affects everyone. Without preventive act... Read More about Control of Antimicrobial Resistance Requires an Ethical Approach.

Mobile Technology Use Across Age Groups in Patients Eligible for Cardiac Rehabilitation: Survey Study (2017)
Journal Article
Gallagher, R., Neubeck, L., Roach, K., Sadler, L., Glinatsis, H., Belshaw, J., Kirkness, A., Zhang, L., Gallagher, P., Paull, G., Gao, Y., Partridge, S. R., & Parker, H. (2017). Mobile Technology Use Across Age Groups in Patients Eligible for Cardiac Rehabilitation: Survey Study. JMIR mHealth and uHealth, 5(10), https://doi.org/10.2196/mhealth.8352

Background: Emerging evidence indicates mobile technology–based strategies may improve access to secondary prevention and reduce risk factors in cardiac patients. However, little is known about cardiac patients’ use of mobile technology, particularly... Read More about Mobile Technology Use Across Age Groups in Patients Eligible for Cardiac Rehabilitation: Survey Study.

Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men (2017)
Journal Article
Irvine, L., Crombie, I. K., Cunningham, K. B., Williams, B., Sniehotta, F. F., Norrie, J., Melson, A. J., Jones, C., Rice, P., Slane, P. W., Achison, M., McKenzie, A., Dimova, E. D., & Allan, S. (2017). Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men. Alcohol and alcoholism : international journal of the Medical Council on Alcoholism, 52(6), 677-684. https://doi.org/10.1093/alcalc/agx067

Objectives
Being obese and drinking more than 14 units of alcohol per week places men at very high risk of developing liver disease. This study assessed the feasibility of a trial to reduce alcohol consumption. It tested the recruitment strategy, en... Read More about Modifying Alcohol Consumption to Reduce Obesity: A Randomized Controlled Feasibility Study of a Complex Community-based Intervention for Men.

A systematic review of cardiac rehabilitation registries (2017)
Journal Article
Poffley, A., Thomas, E., Grace, S. L., Neubeck, L., Gallagher, R., Niebauer, J., & O’Neil, A. (2017). A systematic review of cardiac rehabilitation registries. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487317724576

Introduction: Despite cardiac rehabilitation (CR) being recommended in clinical practice guidelines internationally these services are under-utilised, programs are not standardised and quality improvement methods and outcomes are rarely published. Na... Read More about A systematic review of cardiac rehabilitation registries.

Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration (2017)
Journal Article
Findlay, F., Pohl, J., Svoboda, P., Shakamuri, P., McLean, K., Inglis, N. F., Proudfoot, L., & Barlow, P. G. (2017). Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration. Journal of Immunology, 199(7), 2483-2490. https://doi.org/10.4049/jimmunol.1700706

Host defense peptides, also known as antimicrobial peptides, are key elements of innate host defense. One host defense peptide with well-characterized antimicrobial activity is the human cathelicidin, LL-37. LL-37 has been shown to be upregulated at... Read More about Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration.

Cathelicidins display conserved direct antiviral activity towards rhinovirus. (2017)
Journal Article
Sousa, F. H., Casanova, V., Findlay, F., Stevens, C., Svoboda, P., Pohl, J., Proudfoot, L., & Barlow, P. G. (2017). Cathelicidins display conserved direct antiviral activity towards rhinovirus. Peptides, 95, 76-83. https://doi.org/10.1016/j.peptides.2017.07.013

Human rhinoviruses (HRVs) are the most common cause of viral respiratory tract infections, and are associated with significant morbidity and mortality in immunocompromised individuals and patients with pre-existing pulmonary conditions. The therapeut... Read More about Cathelicidins display conserved direct antiviral activity towards rhinovirus..

Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools (2017)
Presentation / Conference Contribution
Afseth, J., Neubeck, L., Karatzias, T., & Grant, R. (2017, June). Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools. Poster presented at British Neuro Oncology Conference

BACKGROUND: A diagnosis of brain cancer affects nearly 10 000 adults per year in the United Kingdom and has a devastating impact. This is due to the poor prognosis as well as a significant symptom burden, which often includes neurocognitive deficits.... Read More about Holistic Needs Assessment in Brain Cancer Patients: A Systematic Review of Available Tools.

Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease (2017)
Journal Article
Neubeck, L., Cartledge, S., Dawkes, S., & Gallagher, R. (2017). Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease. Current Opinion in Cardiology, 32(5), 567-571. https://doi.org/10.1097/hco.0000000000000428

Purpose of review
Advances in technology coupled with increased penetration of mobile phones and smart devices are rapidly changing healthcare delivery. Mobile phone applications (‘apps’), text messages, and Internet platforms used alone or in combi... Read More about Is there an app for that? Mobile phones and secondary prevention of cardiovascular disease.

Qualitative, critical and discursive methodology for exploring ambivalence around the HPV vaccine amongst marginalised groups (2017)
Presentation / Conference Contribution
Gray Brunton, C., Carnegie, E., Pow, J., Whittaker, A., & Todorova, I. (2017, June). Qualitative, critical and discursive methodology for exploring ambivalence around the HPV vaccine amongst marginalised groups. Poster presented at Building trust, managing risk: vaccine confidence and Human Papillomavirus vaccination

Young people, constructions, context and the Human Papillomavirus (HPV) and HPV vaccine. (2017)
Presentation / Conference Contribution
Gray Brunton, C., & Carnegie, E. (2017, May). Young people, constructions, context and the Human Papillomavirus (HPV) and HPV vaccine. Paper presented at International Week, School of Health and Social Care, Global issues in Healthcare

Background: New social science research approaches are called for to address personal, socio-cultural, and political aspects of specific vaccines in context, given public anxieties and which go beyond the public health aspects. The human papillomavir... Read More about Young people, constructions, context and the Human Papillomavirus (HPV) and HPV vaccine..

Screening for atrial fibrillation: a report of the AF-screen international collaboration. (2017)
Journal Article
Freedman, B., Camm, J., Calkins, H., Healey, J. S., Rosenqvist, M., Wang, J., Albert, C. M., Anderson, C. S., Antoniou, S., Benjamin, E. J., Boriani, G., Brachmann, J., Brandes, A., Chao, T.-F., Conen, D., Engdahl, J., Fauchier, L., Fitzmaurice, D. A., Friberg, L., Gersh, B. J., …Yan, B. P. (2017). Screening for atrial fibrillation: a report of the AF-screen international collaboration. Circulation, 135(19), 1851-1867. https://doi.org/10.1161/CIRCULATIONAHA.116.026693

Approximately 10% of ischemic strokes are associated with atrial fibrillation (AF) first diagnosed at the time of stroke. Detecting asymptomatic AF would provide an opportunity to prevent these strokes by instituting appropriate anticoagulation. The... Read More about Screening for atrial fibrillation: a report of the AF-screen international collaboration..

Modifying Alcohol Consumption to Reduce Obesity (MACRO): development and feasibility trial of a complex community-based intervention for men (2017)
Journal Article
Crombie, I. K., Cunningham, K. B., Irvine, L., Williams, B., Sniehotta, F. F., Norrie, J., Melson, A., Jones, C., Briggs, A., Rice, P. M., Achison, M., McKenzie, A., Dimova, E., & Slane, P. W. (2017). Modifying Alcohol Consumption to Reduce Obesity (MACRO): development and feasibility trial of a complex community-based intervention for men. Health Technology Assessment, 21(19), 1-150. https://doi.org/10.3310/hta21190

Background
Obese men who consume alcohol are at a greatly increased risk of liver disease; those who drink > 14 units of alcohol per week have a 19-fold increased risk of dying from liver disease.
Objectives
To develop an intervention to reduce al... Read More about Modifying Alcohol Consumption to Reduce Obesity (MACRO): development and feasibility trial of a complex community-based intervention for men.

Design and synthesis of novel prodrugs to modulate GABA receptors in cancer (2017)
Thesis
Zhang, H. Design and synthesis of novel prodrugs to modulate GABA receptors in cancer. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/978678

GABA (gamma-amino butanoic acid) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA has been found to play an inhibitory role in some cancers, including colon carcinoma, cholangiocarcinoma, and lung adenocarcinoma.... Read More about Design and synthesis of novel prodrugs to modulate GABA receptors in cancer.

The Lived Experience of Interferon-free Treatments for Hepatitis C: A Thematic Analysis (2017)
Presentation / Conference Contribution
Whiteley, D., Whittaker, A., Elliott, L., & Cunningham-Burley, S. (2017, March). The Lived Experience of Interferon-free Treatments for Hepatitis C: A Thematic Analysis. Poster presented at NHS Lothian R&D Conference 2017

no abstract available.

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease (2017)
Journal Article
Kerr, F., Sofola-Adesakin, O., Ivanov, D. K., Gatliff, J., Gomez Perez-Nievas, B., Bertrand, H. C., Martinez, P., Callard, R., Snoeren, I., Cochemé, H. M., Adcott, J., Khericha, M., Castillo-Quan, J. I., Wells, G., Noble, W., Thornton, J., & Partridge, L. (2017). Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease. PLOS Genetics, 13(3), Article e1006593. https://doi.org/10.1371/journal.pgen.1006593

Nrf2, a transcriptional activator of cell protection genes, is an attractive therapeutic target for the prevention of neurodegenerative diseases, including Alzheimer’s disease (AD). Current Nrf2 activators, however, may exert toxicity and pathway ove... Read More about Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease.

Improving diabetes care for people with intellectual disabilities: a qualitative study exploring the perceptions and experiences of professionals in diabetes and intellectual disability services: Improving diabetes care for people with intellectual disabilities (2017)
Journal Article
Brown, M., Taggart, L., Karatzias, T., Truesdale, M., Walley, R., Northway, R., Macrae, S., Carey, M., & Davies, M. (2017). Improving diabetes care for people with intellectual disabilities: a qualitative study exploring the perceptions and experiences of professionals in diabetes and intellectual disability services: Improving diabetes care for people with intellectual disabilities. Journal of Intellectual Disability Research, 61(5), 435-449. https://doi.org/10.1111/jir.12369

Background: Globally diabetes is increasing with concerns about the impact on outcomes, including premature death and the costs associated with managing the condition. Research indicates that adults with intellectual disabilities (ID) are 2-3 times m... Read More about Improving diabetes care for people with intellectual disabilities: a qualitative study exploring the perceptions and experiences of professionals in diabetes and intellectual disability services: Improving diabetes care for people with intellectual disabilities.