High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects
(2007)
Journal Article
Simpson, R. J., Florida-James, G. D., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H., & Guy, K. (2007). High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. Journal of Applied Physiology, 103(1), 396-401. https://doi.org/10.1152/japplphysiol.00007.2007
Clonal expansion of T lymphocytes in response to antigenic stimulation is a fundamental process of adaptive immunity. As a consequence of clonal expansion, some T lymphocytes acquire a senescent phenotype, fail to replicate in response to further ant... Read More about High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects.