Deletion of endogenous Tau proteins is not detrimental in Drosophila
(2016)
Journal Article
Burnouf, S., Grönke, S., Augustin, H., Dols, J., Gorsky, M. K., Werner, J., Kerr, F., Alic, N., Martinez, P., & Partridge, L. (2016). Deletion of endogenous Tau proteins is not detrimental in Drosophila. Scientific Reports, 6, Article 23102. https://doi.org/10.1038/srep23102
Human Tau (hTau) is a highly soluble and natively unfolded protein that binds to microtubules within neurons. Its dysfunction and aggregation into insoluble paired helical filaments is involved in the pathogenesis of Alzheimer’s disease (AD), constit... Read More about Deletion of endogenous Tau proteins is not detrimental in Drosophila.