Physiological variables and performance markers of serving soldiers from two “elite” units of the British Army (2006)
Journal Article
Simpson, R. J., Gray, S. C., & Florida-James, G. D. (2006). Physiological variables and performance markers of serving soldiers from two “elite” units of the British Army. Journal of Sports Sciences, 24(6), 597-604. https://doi.org/10.1080/02640410500230811

The aim of this study was to compare selected physiological variables and performance markers of soldiers from two “elite” units of the British Army. Ten soldiers from each of the two units were recruited for this study (n = 20). All participants com... Read More about Physiological variables and performance markers of serving soldiers from two “elite” units of the British Army.

The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein. (2006)
Journal Article
Johnson, D. A., & Smith, K. (2006). The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein. Biomedical Chromatography, 20, 551-560. https://doi.org/10.1002/bmc.641

One of the most ubiquitous plasma proteins, -1-acid glycoprotein (AGP), has a high affinity, low capacity binding for basic drugs positively charged at physiological pH. Moreover, as an acute phase protein its level is increased in various disease st... Read More about The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein..

Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling (2006)
Journal Article
Nevill, A. M., Jobson, S. A., Davison, R. C. R., & Jeukendrup, A. E. (2006). Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling. European Journal of Applied Physiology, 97(4), 424-431. https://doi.org/10.1007/s00421-006-0189-6

The purpose of this article was to establish whether previously reported oxygen-to-mass ratios, used to predict flat and hill-climbing cycling performance, extend to similar power-to-mass ratios incorporating other, often quick and convenient measure... Read More about Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling.

Testicular dysgenesis syndrome: from human disorders to mechanistic studies in an animal model (2006)
Presentation / Conference Contribution
Hutchison, G., Sharpe, R., Mahood, K., Hallmark, N., McKinnell, C., & Ferrara, D. (2006, November). Testicular dysgenesis syndrome: from human disorders to mechanistic studies in an animal model. Presented at International Symposium on Animal Biology of Reproduction 2006, Belo Horizonte, Brazil

The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53 (2006)
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., & Guy, K. (2006). The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53. European Journal of Applied Physiology, 97(1), 109-121. https://doi.org/10.1007/s00421-006-0146-4

This study examined the effects of intensive, moderate and downhill treadmill running on blood lymphocyte expression of adhesion/activation (AA) molecules. Trained subjects completed three treadmill-running protocols of identical duration: (1) an int... Read More about The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (β2 integrin) and CD53.

Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. (2005)
Journal Article
Moller, W., Brown, D. M., Kreyling, L., & Stone, V. (2005). Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium. Particle and fibre toxicology, 2, 7. https://doi.org/10.1186/1743-8977-2-7

Background
Particulate air pollution is reported to cause adverse health effects in susceptible individuals. Since most of these particles are derived form combustion processes, the primary composition product is carbon with a very small diameter (u... Read More about Ultrafine particles cause cytoskeletal dysfunctions in macrophages: role of intracellular calcium..

Consequences of the Evolution of the GABAA Receptor Gene Family (2005)
Journal Article
Darlison, M. G., Pahal, I., & Thode, C. (2005). Consequences of the Evolution of the GABAA Receptor Gene Family. Cellular and Molecular Neurobiology, 25(3-4), 607-624. https://doi.org/10.1007/s10571-005-4004-4

1. This paper reviews the evolution of the family of genes present in mammals and other vertebrates that encode $γ$-aminobutyric acid (GABA) type A (GABAA) receptors, which are the major inhibitory neurotransmitter receptors in the central nervous sy... Read More about Consequences of the Evolution of the GABAA Receptor Gene Family.

Early socio-emotional experience induces expression of the immediate-early gene Arc/arg3.1 (activity-regulated cytoskeleton-associated protein/activity-regulated gene) in learning-relevant brain regions of the newborn chick (2005)
Journal Article
Bock, J., Thode, C., Hannemann, O., Braun, K., & Darlison, M. (2005). Early socio-emotional experience induces expression of the immediate-early gene Arc/arg3.1 (activity-regulated cytoskeleton-associated protein/activity-regulated gene) in learning-relevant brain regions of the newborn chick. Neuroscience, 133(3), 625-633. https://doi.org/10.1016/j.neuroscience.2005.02.048

We have cloned a full-length complementary {DNA} from the chicken (Gallus gallus domesticus), which encodes a polypeptide that exhibits ∼75% identity to the product of the mammalian gene Arc (activity-regulated cytoskeleton-associated protein), also... Read More about Early socio-emotional experience induces expression of the immediate-early gene Arc/arg3.1 (activity-regulated cytoskeleton-associated protein/activity-regulated gene) in learning-relevant brain regions of the newborn chick.

Immune alterations, lipid peroxidation, and muscle damage following a hill race. (2005)
Journal Article
Simpson, R. J., Wilson, M. R., Black, J., Ross, J. A., Whyte, G. P., Guy, K., & Florida-James, G. (2005). Immune alterations, lipid peroxidation, and muscle damage following a hill race. Canadian Journal of Applied Physiology, 30(2), 196-211. https://doi.org/10.1139/h05-115

Hill races usually include large downhill running sections, which can induce significant degrees of muscle damage in a field setting. This study examined the link between muscle damage, oxidative stress, and immune perturbations following a 7-km moun... Read More about Immune alterations, lipid peroxidation, and muscle damage following a hill race..

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. (2005)
Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005). Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933

Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main determinant of parasite survival. In a laboratory model of infection, using... Read More about Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo..

Impact of marathon running on cardiac structure and function in recreational runners (2005)
Journal Article
Whyte, G. P., George, K., Shave, R., Dawsons, E., Stephenson, C., Edwards, B., Gaze, D., Oxborough, D., Forster, J., & Simpson, R. J. (2005). Impact of marathon running on cardiac structure and function in recreational runners. Clinical Science, 108(1), 73-80. https://doi.org/10.1042/CS20040186

The present study examined the relationship between LV (left ventricular) function, markers of cardiac-specific damage and markers of oxidative stress in recreational runners following a marathon. Runners (n=52; 43 male and nine female; age, 35±10 ye... Read More about Impact of marathon running on cardiac structure and function in recreational runners.

Age-related changes in maximal power and heart rate recorded during a ramped test in 114 cyclists age 15-73 years. (2005)
Journal Article
Balmer, J., Potter, C. R., Bird, S. R., & Davison, R. (2005). Age-related changes in maximal power and heart rate recorded during a ramped test in 114 cyclists age 15-73 years. Journal of Aging and Physical Activity, 13, 125-136

This study assessed age-related changes in power and heart rate in 114 competitive male cyclists age 15–73 years. Participants completed a maximal Kingcycle™ ergometer test with maximal ramped minute power (RMPmax, W) recorded as the highest average... Read More about Age-related changes in maximal power and heart rate recorded during a ramped test in 114 cyclists age 15-73 years..

Metaphase Chromosome (2004)
Book Chapter
Vass, S., & Heck, M. M. (2004). Metaphase Chromosome. In W. J. Lennarz, & M. Daniel Lane (Eds.), Encyclopedia of Biological Chemistry (666-671). Elsevier. https://doi.org/10.1016/b0-12-443710-9/00119-8

Effects of PM10 in human peripheral blood monocytes and J774 macrophages (2004)
Journal Article
Brown, D., Donaldson, K., & Stone, V. (2004). Effects of PM10 in human peripheral blood monocytes and J774 macrophages. Respiratory Research, 5, Article 29. https://doi.org/10.1186/1465-9921-5-29

The effects of PM10, one of the components of particulate air pollution, was investigated using human monocytes and a mouse macrophage cell line (J774). The study aimed to investigate the role of these nanoparticles on the release of the pro-inflamma... Read More about Effects of PM10 in human peripheral blood monocytes and J774 macrophages.

Perivascular nerves induce cardiorespiratory reflexes in response to algogens in anaesthetised rats (2004)
Journal Article
Smith, P. J. W., & McQueen, D. S. (2004). Perivascular nerves induce cardiorespiratory reflexes in response to algogens in anaesthetised rats. Neuroscience Research, 50(3), 271-281. https://doi.org/10.1016/j.neures.2004.07.006

In the present study we measured cardiovascular and respiratory reflexes evoked by administration of bradykinin and capsaicin into the hindlimb vasculature of anaesthetised rats, whilst simultaneously recording activity of sensory afferents on the ad... Read More about Perivascular nerves induce cardiorespiratory reflexes in response to algogens in anaesthetised rats.

Athens 2004: the pollution climate and athletic performance (2004)
Journal Article
Florida-James, G., Donaldson, K., & Stone, V. (2004). Athens 2004: the pollution climate and athletic performance. Journal of Sports Sciences, 22(10), 967-980. https://doi.org/10.1080/02640410400000272

Athens sits in a basin approximately 450 [km.sup.2] in area, surrounded by mountains and open sea. Anthropogenic emissions in conjunction with the topographical and meteorological conditions can result in high air pollution within the city. The pollu... Read More about Athens 2004: the pollution climate and athletic performance.

Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis. (2004)
Journal Article
Rae, M. T., Niven, D., Ross, A., Forster, T., Lathe, R., Critchley, H. O. D., Ghazal, P., & Hillier, S. G. (2004). Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis. Journal of Endocrinology, 183, 19-28. https://doi.org/10.1677/joe.1.05754

The human ovarian surface epithelium (HOSE) is a common site of gynaecological disease including endometriosis and ovarian cancer, probably due to serial injury-repair events associated with successive ovulations. To comprehend the importance of ster... Read More about Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis..

Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis (2004)
Journal Article
Valdeolmillos, A., Rufas, J. S., Suja, J. A., Vass, S., Heck, M. M., Martínez-A, C., & Barbero, J. L. (2004). Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis. Biology of the Cell, 96(6), 457-462. https://doi.org/10.1016/j.biolcel.2004.04.011

Sister chromatid cohesion in eukaryotes is maintained mainly by a conserved multiprotein complex termed cohesin. Drad21 and DSA1 are the Drosophila homologues of the yeast Scc1 and Scc3 cohesin subunits, respectively. We recently identified a Drosoph... Read More about Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis.

Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats (2004)
Journal Article
McQueen, D. S., Bond, S. M., Smith, P. J., Balali-Mood, K., & Smart, D. (2004). Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats. European Journal of Pharmacology, 491(2-3), 181-189. https://doi.org/10.1016/j.ejphar.2004.03.045

The results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (±) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at cannabinoid (CB) receptors, does not affect respiration or blood pressure when... Read More about Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats.

Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis (2004)
Journal Article
Keir, P. A., Brown, D. M., Clouter-Baker, A., Harcus, Y. M., & Proudfoot, L. (2004). Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis. Parasite Immunology, 26(3), 137-139. https://doi.org/10.1111/j.0141-9838.2004.00692.x

It has been reported that excretory–secretory (ES) material from the parasitic nematode Nippostrongylus brasiliensis has potential modulatory effects on the host's immune system. We observed that intratracheal instillation of ES from the L3 stage of... Read More about Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis.