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The 4 ‘A’s test for detecting delirium in acute medical patients: a diagnostic accuracy study (2019)
Journal Article
MacLullich, A. M., Shenkin, S. D., Goodacre, S., Godfrey, M., Hanley, J., Stíobhairt, A., Lavender, E., Boyd, J., Stephen, J., Weir, C., MacRaild, A., Steven, J., Black, P., Diernberger, K., Hall, P., Tieges, Z., Fox, C., Anand, A., Young, J., Siddiqi, N., & Gray, A. (2019). The 4 ‘A’s test for detecting delirium in acute medical patients: a diagnostic accuracy study. Health Technology Assessment, 23(40), 1-194. https://doi.org/10.3310/hta23400

Background: Delirium is a common and serious neuropsychiatric syndrome, usually triggered by illness or drugs. It remains underdetected. One reason for this is a lack of brief, pragmatic assessment tools. The 4 ‘A’s test (Arousal, Attention, Abbrevia... Read More about The 4 ‘A’s test for detecting delirium in acute medical patients: a diagnostic accuracy study.

Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis (2019)
Journal Article
Karatzias, T., Murphy, P., Cloitre, M., Bisson, J., Roberts, N., Shevlin, M., Hyland, P., Maercker, A., Ben-Ezra, M., Coventry, P., Mason-Roberts, S., Bradley, A., & Hutton, P. (2019). Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis. Psychological Medicine, 49(11), 1761-1775. https://doi.org/10.1017/S0033291719000436

Background: The 11th revision to the WHO International Classification of Diseases (ICD-11) identified Complex Posttraumatic Stress Disorder (CPTSD) as a new condition. There is a pressing need to identify effective CPTSD interventions. Methods: We co... Read More about Psychological interventions for ICD-11 Complex PTSD symptoms: Systematic review and meta-analysis.

Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety (2019)
Journal Article
Morgenroth, E., Orlov, N., Lythgoe, D. J., Stone, J. M., Barker, H., Munro, J., Eysenck, M., & Allen, P. (2019). Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety. Cortex, 117, 53-63. https://doi.org/10.1016/j.cortex.2019.02.021

Trait anxiety can affect cognitive control resulting in ineffective and/or inefficient task performance. Moreover, previous functional Magnetic Resonance Imaging (fMRI) studies have reported altered dorsolateral prefrontal cortex (DLPFC) activity in... Read More about Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety.

A mixed‐methods, randomized controlled feasibility trial of Eye Movement Desensitization and Reprocessing (EMDR) plus Standard Care (SC) versus SC alone for DSM‐5 Posttraumatic Stress Disorder (PTSD) in adults with intellectual disabilities (2019)
Journal Article
Karatzias, T., Brown, M., Taggart, L., Truesdale, M., Sirisena, C., Walley, R., Mason-Roberts, S., Bradley, A., & Paterson, D. (2019). A mixed‐methods, randomized controlled feasibility trial of Eye Movement Desensitization and Reprocessing (EMDR) plus Standard Care (SC) versus SC alone for DSM‐5 Posttraumatic Stress Disorder (PTSD) in adults with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities, 32(4), 806-818. https://doi.org/10.1111/jar.12570

Objective: To report the results of the first randomised feasibility trial of Eye Movement Desensitisation and Reprocessing (EMDR) plus Standard Care (SC) vs. SC alone for DSM-5 Posttraumatic Stress Disorder (PTSD) in adults with intellectual disabil... Read More about A mixed‐methods, randomized controlled feasibility trial of Eye Movement Desensitization and Reprocessing (EMDR) plus Standard Care (SC) versus SC alone for DSM‐5 Posttraumatic Stress Disorder (PTSD) in adults with intellectual disabilities.

A Cross‐Cultural Comparison of ICD‐11 Complex Posttraumatic Stress Disorder Symptom Networks in Austria, the United Kingdom, and Lithuania (2019)
Journal Article
Knefel, M., Lueger-Schuster, B., Bisson, J., Karatzias, T., Kazlauskas, E., & Roberts, N. P. (2020). A Cross‐Cultural Comparison of ICD‐11 Complex Posttraumatic Stress Disorder Symptom Networks in Austria, the United Kingdom, and Lithuania. Journal of Traumatic Stress, 33(1), 41-51. https://doi.org/10.1002/jts.22361

The 11th revision of the World Health Organization's International Classification of Diseases (ICD-11) may include a new disorder, Complex Posttraumatic Stress Disorder (CPTSD). The network approach to psychopathology enables investigation of the str... Read More about A Cross‐Cultural Comparison of ICD‐11 Complex Posttraumatic Stress Disorder Symptom Networks in Austria, the United Kingdom, and Lithuania.

The replicability of ICD-11 complex post-traumatic stress disorder symptom networks in adults (2019)
Journal Article
Knefel, M., Karatzias, T., Ben-Ezra, M., Cloitre, M., Lueger-Schuster, B., & Maercker, A. (2019). The replicability of ICD-11 complex post-traumatic stress disorder symptom networks in adults. British Journal of Psychiatry, 214(6), 361-368. https://doi.org/10.1192/bjp.2018.286

Background: The 11th revision of the World Health Organization's International Classification of Diseases (ICD-11) includes a new disorder, Complex Posttraumatic Stress Disorder (CPTSD). A network approach to CPTSD will enable investigation of the st... Read More about The replicability of ICD-11 complex post-traumatic stress disorder symptom networks in adults.

A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications (2018)
Journal Article
Paterson, C., Karatzias, T., Harper, S., Dougall, N., Dickson, A., & Hutton, P. (2019). A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications. British Journal of Clinical Psychology, 58(2), 211-230. https://doi.org/10.1111/bjc.12209

Objectives
Acute psychiatric inpatient wards are characterised by minimal provision of therapeutic activities and high readmission rates. Implementation of a comprehensive inpatient psychological intervention service has been recommended to overcome... Read More about A feasibility study of a cross-diagnostic, CBT-based psychological intervention for acute mental health inpatients: Results, challenges, and methodological implications.

Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms? (2018)
Journal Article
Hutton, P., Di Rienzo, F., Turkington, D., Spencer, H., & Taylor, P. (2019). Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?. Schizophrenia Bulletin, 45(1), 37-47. https://doi.org/10.1093/schbul/sby153

Between 5 and 10 percent of people with psychosis will die by suicide, a rate which is 20 to 75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals... Read More about Suicidal ideation in people with psychosis not taking antipsychotic medication: Do negative appraisals and negative metacognitive beliefs mediate the effect of symptoms?.

Quality not quantity: loneliness subtypes, psychological trauma, and mental health in the US adult population (2018)
Journal Article
Power, J. M., Hyland, P., Shevlin, M., Cloitre, M., Karatzias, T., Vallières, F., McGinty, G., Fox, R., & Mchugh Power, J. (2019). Quality not quantity: loneliness subtypes, psychological trauma, and mental health in the US adult population. Social Psychiatry and Psychiatric Epidemiology, 54(9), 1089-1099. https://doi.org/10.1007/s00127-018-1597-8

Purpose: Loneliness is a recognised public-health concern that is traditionally regarded as a unidimensional construct. Theories of loneliness predict the existence of subtypes of loneliness. In this study, latent class analysis (LCA) was used to tes... Read More about Quality not quantity: loneliness subtypes, psychological trauma, and mental health in the US adult population.

Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population (2018)
Journal Article
Carmichael, D. A., Smees, R., Shillcock, R. C., & Simner, J. (2019). Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population. British Journal of Psychology, 110(3), 530-548. https://doi.org/10.1111/bjop.12354

Synaesthesia has long been considered a benign alternative form of perception most often associated with positive rather than negative outcomes. The condition has been associated with a variety of cognitive and perceptual advantages, including benefi... Read More about Is there a burden attached to synaesthesia? Health screening of synaesthetes in the general population.

The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis (2018)
Journal Article
Turner, D. T., MacBeth, A., Larkin, A., Moritz, S., Livingstone, K., Campbell, A., & Hutton, P. (2019). The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis. Schizophrenia Bulletin, 45(4), 784-793. https://doi.org/10.1093/schbul/sby136

Background
Evidence-based psychological interventions to support treatment decision-making capacity (‘capacity’) in psychosis do not currently exist. This study sought to establish whether reducing the extent to which this group form conclusions bas... Read More about The effect of reducing the 'jumping to conclusions' bias on treatment decision-making capacity in psychosis: A randomised controlled trial with mediation analysis.

Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks (2018)
Journal Article
Woodrow, A., Sparks, S., Bobrovskaia, V., Paterson, C., Murphy, P., & Hutton, P. (2019). Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks. Psychological Medicine, 49(1), 32-48. https://doi.org/10.1017/S0033291718002660

To identify factors which may help or hinder decision-making ability in people with psychosis, we did a systematic review and meta-analysis of their performance on the Iowa and Cambridge Gambling Tasks. Analysis of 47 samples found they had moderatel... Read More about Decision-making ability in psychosis: a systematic review and meta-analysis of the magnitude, specificity and correlates of impaired performance on the Iowa and Cambridge Gambling Tasks.

Derealisation and self-harm strategies are used to regulate disgust, fear and sadness in adult survivors of childhood sexual abuse (2018)
Journal Article
Bradley, A., Karatzias, T., & Coyle, E. (2019). Derealisation and self-harm strategies are used to regulate disgust, fear and sadness in adult survivors of childhood sexual abuse. Clinical Psychology and Psychotherapy, 26(1), 94-104. https://doi.org/10.1002/cpp.2333

Emotion regulation (ER) difficulties have been identified as an important target for clinical intervention in the treatment of posttraumatic stress disorder (PTSD) symptoms in survivors of childhood sexual abuse (CSA). However, there is limited resea... Read More about Derealisation and self-harm strategies are used to regulate disgust, fear and sadness in adult survivors of childhood sexual abuse.

A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder (2018)
Journal Article
Mahoney, A., Karatzias, T., & Hutton, P. (2018). A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder. Journal of Affective Disorders, https://doi.org/10.1016/j.jad.2018.09.059

Background: No previous meta-analyses have specifically investigated the effectiveness of psychological group therapy for symptoms associated with complex interpersonal trauma, including whether trauma memory processing (TMP) therapies are superior t... Read More about A systematic review and meta-analysis of group treatments for adults with symptoms associated with complex post-traumatic stress disorder.

The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD (2018)
Journal Article
Cloitre, M., Shevlin, M., Brewin, C. R., Bisson, J. I., Roberts, N. P., Maercker, A., Karatzias, T., & Hyland, P. (2018). The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD. Acta Psychiatrica Scandinavica, 138(6), 536-546. https://doi.org/10.1111/acps.12956

Objective: The purpose of this study was to finalize the development of the International Trauma Questionnaire (ITQ); a self-report diagnostic measure of Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD), as defined in the 11th version of... Read More about The International Trauma Questionnaire: development of a self-report measure of ICD-11 PTSD and complex PTSD.

PTSD post-childbirth: a systematic review of women’s and midwives’ subjective experiences of care provider interaction (2018)
Journal Article
Patterson, J., Hollins Martin, C., & Karatzias, T. (2019). PTSD post-childbirth: a systematic review of women’s and midwives’ subjective experiences of care provider interaction. Journal of Reproductive and Infant Psychology, 37(1), 56-83. https://doi.org/10.1080/02646838.2018.1504285

Objective: To review primary research from within the literature regarding PTSD Post-Childbirth (PTSD-PC), that focussed on Quality of Provider Interaction (QPI) from either the perspective of women who have developed PTSD-PC, or midwives.
Backgroun... Read More about PTSD post-childbirth: a systematic review of women’s and midwives’ subjective experiences of care provider interaction.

Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome? (2018)
Journal Article
Spencer, H. M., McMenamin, M., Emsley, R., Turkington, D., Dunn, G., Morrison, A. P., Brabban, A., Hutton, P., & Dudley, R. (2018). Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?. Schizophrenia Research, 202, 385-386. https://doi.org/10.1016/j.schres.2018.07.016

This study investigated the effect of “dose” and the components of Cognitive Behavioral Therapy (CBT) on treatment effects. It is a secondary analysis of the ACTION (Assessment of Cognitive Therapy Instead of Neuroleptics) trial which investigated CB... Read More about Cognitive Behavioral Therapy for antipsychotic-free schizophrenia spectrum disorders: Does therapy dose influence outcome?.

Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial (2018)
Journal Article
Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S. E., French, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R. E., Davies, L., Kingdon, D., Aydinlar, S., Courtley, J., …Tully, S. (2018). Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial. Lancet Psychiatry, 5(8), 633-643. https://doi.org/10.1016/s2215-0366%2818%2930184-6

Background
Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30–40% of patients have an insufficient response, and others are unable to tolerate it. Evidence for any augmentation strategies is scarce. We aimed to... Read More about Cognitive behavioural therapy in clozapine-resistant schizophrenia (FOCUS): an assessor-blinded, randomised controlled trial.

From child maltreatment to ICD-11 complex post-traumatic stress symptoms: The role of emotion regulation and re-victimisation (2018)
Journal Article
Knefel, M., Lueger-Schuster, B., Karatzias², T., Shevlin, M., & Hyland, P. (2019). From child maltreatment to ICD-11 complex post-traumatic stress symptoms: The role of emotion regulation and re-victimisation. Journal of Clinical Psychology, 75(3), 392-403. https://doi.org/10.1002/jclp.22655

Objective: Complex Posttraumatic Stress Disorder (CPTSD) will be introduced in ICD-11 and comprises symptoms of PTSD and disturbances in self-organisation (DSO). The association of trauma with PTSD and DSO is not yet fully understood. We investigated... Read More about From child maltreatment to ICD-11 complex post-traumatic stress symptoms: The role of emotion regulation and re-victimisation.

What influences social outcomes among offenders with personality disorder: A systematic review (2018)
Journal Article
Connell, C., Furtado, V., McKay, E. A., & Singh, S. P. (2018). What influences social outcomes among offenders with personality disorder: A systematic review. Criminal Behaviour and Mental Health, https://doi.org/10.1002/cbm.2082

Background:
Personality disorder is highly prevalent in offender populations and is associated with poor health, criminal justice and social outcomes. Research has been conducted into factors that influence offending and health, but, in order to im... Read More about What influences social outcomes among offenders with personality disorder: A systematic review.