Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential (2019)
Journal Article
Sharma, A., Goring, A., Staines, K., Emery, R., Pitsillides, A. A., Oreffo, R. O., Mahajan, S., & Clarkin, C. E. (2020). Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential. Matrix Biology Plus, 5, https://doi.org/10.1016/j.mbplus.2019.100018

Mineralization of bone is achieved by the sequential maturation of the immature amorphous calcium phase to mature hydroxyapatite and is central to the process of bone development and repair. To study normal and dysregulated mineralization in vitro, s... Read More about Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential.

Dynamics Analysis of a Turbulent Methane Flame in MILD Combustion Conditions (2019)
Presentation / Conference Contribution
Manias, D. M., Tingas, E.-A., Im, H. G., & Minamoto, Y. (2019, January). Dynamics Analysis of a Turbulent Methane Flame in MILD Combustion Conditions. Presented at AIAA Scitech 2019 Forum, San Diego, California

The dominant physical processes that characterize the combustion of a lean methane/air mixture, diluted with exhaust gas recirculation (EGR), under turbulent MILD premixed conditions are identified using the combined approaches of Computational Singu... Read More about Dynamics Analysis of a Turbulent Methane Flame in MILD Combustion Conditions.

The Effects of morpholine pre-treated and carboxymethylated cellulose nanofibrils on the properties of alginate-based hydrogels (2018)
Journal Article
Onyianta, A. J., Castellano, M., Dorris, M., Williams, R. L., & Vicini, S. (2018). The Effects of morpholine pre-treated and carboxymethylated cellulose nanofibrils on the properties of alginate-based hydrogels. Carbohydrate Polymers, 198, 320-327. https://doi.org/10.1016/j.carbpol.2018.06.084

The effects of varying percentage loadings of morpholine pre-treated cellulose nanofibrils (MCNF) and carboxymethylated cellulose nanofibrils (CMCNF) on the aqueous swelling, compressive modulus and viscoelastic properties of calcium-ion-crosslinked... Read More about The Effects of morpholine pre-treated and carboxymethylated cellulose nanofibrils on the properties of alginate-based hydrogels.

A computational analysis of methanol autoignition enhancement by dimethyl ether addition in a counterflow mixing layer (2018)
Journal Article
Song, W., Tingas, E.-A., & Im, H. G. (2018). A computational analysis of methanol autoignition enhancement by dimethyl ether addition in a counterflow mixing layer. Combustion and Flame, 195, 84-98. https://doi.org/10.1016/j.combustflame.2018.03.037

To provide fundamental insights into the ignition enhancement of methanol (MeOH) by the addition of the more reactive dimethyl ether (DME), computational parametric studies were conducted in a one-dimensional counterflow fuel versus air mixing layer... Read More about A computational analysis of methanol autoignition enhancement by dimethyl ether addition in a counterflow mixing layer.

Analysis of Hydrogen/Air Turbulent Premixed Flames at Different Karlovitz Numbers Using Computational Singular Perturbation (2018)
Presentation / Conference Contribution
Manias, D. M., Tingas, E.-A., Hernández Pérez, F. E., Im, H. G., Galassi, R. M., Ciottoli, P. P., & Valorani, M. (2018, January). Analysis of Hydrogen/Air Turbulent Premixed Flames at Different Karlovitz Numbers Using Computational Singular Perturbation. Presented at 2018 AIAA Aerospace Sciences Meeting, Kissimmee, Florida

The dynamics and structure of two turbulent H2/air premixed flames, representative of the corrugated flamelet (Case 1) and thin reaction zone (Case 2) regimes, are analyzed and compared, using the computational singular perturbation (CSP) tools, by i... Read More about Analysis of Hydrogen/Air Turbulent Premixed Flames at Different Karlovitz Numbers Using Computational Singular Perturbation.

Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics. (2017)
Thesis
Oluwadare, E. Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/1036075

The nematode Caenorhabditis elegans is an alternative model used in biomedical research for the investigation of descriptive and mechanistic toxicity assessment of chemicals. There are considerable differences in published data, especially in terms o... Read More about Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics..

Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting (2016)
Journal Article
Ramsden, J., Reid, M., Whatley, V., & Dancer, S. (2016). Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting. Journal of Biological Physics and Chemistry, 16(3), 131-136. https://doi.org/10.4024/16ra16a.jbpc.16.03

Attempts are being made to incorporate copper into clear varnish in order to coat environmental surfaces in hospitals with the long-term goal of reducing healthcare-acquired infections (HAI). The performance of a nanocopper-containing polyacrylic emu... Read More about Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting.

Aqueous solutions of HEC and hmHEC: effects of molecular mass versus hydrophobic associations on hydrodynamic and thermodynamic parameters. (2016)
Journal Article
Vadodaria, S. S., & English, R. J. (2016). Aqueous solutions of HEC and hmHEC: effects of molecular mass versus hydrophobic associations on hydrodynamic and thermodynamic parameters. Cellulose, 23(2), 1107-1121. https://doi.org/10.1007/s10570-016-0861-x

Aqueous solutions of amphiphilic polymers
usually comprise of inter- and intramolecular
associations of hydrophobic groups often leading to a
formation of a rheologically significant reversible
network at low concentrations that can be identified... Read More about Aqueous solutions of HEC and hmHEC: effects of molecular mass versus hydrophobic associations on hydrodynamic and thermodynamic parameters..

Extensional rheometry of cellulose ether solutions: flow instability (2015)
Journal Article
Vadodaria, S. S., & English, R. J. (2015). Extensional rheometry of cellulose ether solutions: flow instability. Cellulose, 23(1), 339-355. https://doi.org/10.1007/s10570-015-0838-1

Capillary breakup extensional rheometry
of semi-dilute hydroxyethyl cellulose (HEC) solutions
was performed under several step-stretch conditions.
The resulting parameters, i.e. terminal steady state
extensional viscosity (gE) and the timescale f... Read More about Extensional rheometry of cellulose ether solutions: flow instability.

The Extractive Content of Scottish Roundwood - October 2015 (2015)
Report
Adams, S. H. (2015). The Extractive Content of Scottish Roundwood - October 2015

Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression (2013)
Journal Article
Gordon, K., Clouaire, T., Bao, X. X., Kemp, S. E., Xenophontos, M., de Las Heras, J. I., & Stancheva, I. (2014). Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression. Nucleic Acids Research, 42(6), 3529-3541. https://doi.org/10.1093/nar/gkt1351

Tumourigenic transformation of normal cells into cancer typically involves several steps resulting in acquisition of unlimited growth potential, evasion of apoptosis and non-responsiveness to growth inhibitory signals. Both genetic and epigenetic cha... Read More about Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression.

A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA (2012)
Journal Article
Nguyen, H. V., Zhao, Z.-Y., Sallustrau, A., Horswell, S. L., Male, L., Mulas, A., & Tucker, J. H. R. (2012). A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA. Chemical Communications, 48, 12165. https://doi.org/10.1039/C2CC36428J

The design, synthesis and electrochemical behaviour of an oligomer consisting of linked thymine-functionalised ferrocene units are reported, which, as a so-called form of ferrocene nucleic acid (FcNA), acts as a structural mimic of DNA.

Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device (2012)
Thesis
O'Connor, L. Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/5260

The main piece of legislation which addresses illicit drugs in the UK is the Misuse of Drugs Act 1971. The Act was designed to prevent the use of drugs which are 'capable of having harmful effects sufficient to constitute a social problem'.
The Roa... Read More about Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device.

Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824 (2012)
Thesis
Almohaish, A. A. Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/5692

In low GC Gram-positive bacteria, the phenomenon of carbon catabolite repression is dependent on a metabolite-activated bifunctional protein kinase/phosphorylase. In Clostridium acetobutylicum ATCC 824, the hprK gene encodes the bifunctional protein... Read More about Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824.

Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe (2012)
Journal Article
Zhao, Z.-Y., San, M., Duprey, J.-L. H. A., Arrand, J. R., Vyle, J. S., & Tucker, J. H. R. (2012). Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe. Bioorganic and Medicinal Chemistry Letters, 22(1), 129-132. https://doi.org/10.1016/j.bmcl.2011.11.053

Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing internal anthracene fluorophores proximal to the SNP site. Depending upon the nature of the... Read More about Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe.

Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe (2011)
Journal Article
Duprey, J.-L. H. A., Zhao, Z.-Y., Bassani, D. M., Manchester, J., Vyle, J. S., & Tucker, J. H. R. (2011). Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe. Chemical Communications, 47, 6629. https://doi.org/10.1039/c1cc11205h

A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modification C/5-MeCvia a hybridisation sensing assay.

The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone. (2010)
Thesis
Behan, J. L. The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/4446

Dependence on heroin and other opioids represents a considerable problem worldwide. There is a continual need to improve therapy and/ or find more efficacious alternatives if these issues are to be addressed. The most commonly implemented pharmacol... Read More about The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone..

Simulations and experiments of self-associating telechelic polymer solutions (2008)
Journal Article
Cass, M. J., Heyes, D. M., Blanchard, R.-L., & English, R. J. (2008). Simulations and experiments of self-associating telechelic polymer solutions. Journal of physics. an Institute of Physics journal. Condensed matter, 20(33), 335103. https://doi.org/10.1088/0953-8984/20/33/335103

A Brownian dynamics computer simulation study of a highly coarse-grained model of telechelic associating polymers has been carried out. In a critical concentration range the model produces the so-called 'loops-to-bridges' transition, thought to exist... Read More about Simulations and experiments of self-associating telechelic polymer solutions.

The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings (2008)
Journal Article
Szczygieł, B., & Turkiewicz, A. (2008). The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings. Applied Surface Science, 254(22), 7410-7416. https://doi.org/10.1016/j.apsusc.2008.05.342

Composite four-component Ni–W–P–ZrO2 coatings were electrolessly deposited from a bath with different concentrations of aminoacetic acid (glycine—the complexing agent), sodium tungstate(VI) and zirconium(IV) oxide at different pH values. Concentratio... Read More about The effect of suspension bath composition on the composition, topography and structure of electrolessly deposited composite four-component Ni–W–P–ZrO2 coatings.

The influence of the extensional viscosity of very low concentrations of high molecular mass water-soluble polymers on atomisation and droplet impact (2008)
Journal Article
Williams, P. A., English, R. J., Blanchard, R. L., Rose, S. A., Lyons, L., & Whitehead, M. (2008). The influence of the extensional viscosity of very low concentrations of high molecular mass water-soluble polymers on atomisation and droplet impact. Pest management science, 64(5), 497-504. https://doi.org/10.1002/ps.1523

BACKGROUND: Water-soluble polymers are increasingly added to herbicide and pesticide formulations at very low concentrations (100–1000 mg L−1) in order to control the spray characteristics, notably to reduce spray drift and influence droplet bounce.... Read More about The influence of the extensional viscosity of very low concentrations of high molecular mass water-soluble polymers on atomisation and droplet impact.