Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis

Keir, P. A.; Brown, D. M.; Clouter-Baker, A.; Harcus, Y. M.; Proudfoot, L.

Abstract

It has been reported that excretory–secretory (ES) material from the parasitic nematode Nippostrongylus brasiliensis has potential modulatory effects on the host's immune system. We observed that intratracheal instillation of ES from the L3 stage of the parasite reduced neutrophil numbers in LPS-induced inflammation as assessed by bronchoalveolar lavage.

Citation

Keir, P. A., Brown, D. M., Clouter-Baker, A., Harcus, Y. M., & Proudfoot, L. (2004). Inhibition of neutrophil recruitment by ES of Nippostrongylus brasiliensis. Parasite Immunology, 26(3), 137-139. https://doi.org/10.1111/j.0141-9838.2004.00692.x

• Journal Article Type: Article
• Publication Date: 2004-03
• Deposit Date: Apr 28, 2008
• Journal: Parasite Immunology
• Print ISSN: 0141-9838
• Electronic ISSN: 1365-3024
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 26
• Issue: 3
• Pages: 137-139
• DOI: https://doi.org/10.1111/j.0141-9838.2004.00692.x
• Keywords: Bronchoalveolar lavage; Neutrophil; Nippostron-gylus brasiliensis
• Public URL: http://researchrepository.napier.ac.uk/id/eprint/1648
• Publisher URL: http://dx.doi.org/10.1111/j.0141-9838.2004.00692.x