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Constructing more informative plant–pollinator networks: visitation and pollen deposition networks in a heathland plant community (2015)
Journal Article
Ballantyne, G., Baldock, K. C. R., & Willmer, P. G. (2015). Constructing more informative plant–pollinator networks: visitation and pollen deposition networks in a heathland plant community. Proceedings of the Royal Society B: Biological Sciences, 282(1814), Article 20151130. https://doi.org/10.1098/rspb.2015.1130

Interaction networks are widely used as tools to understand plant–pollinator communities, and to examine potential threats to plant diversity and food security if the ecosystem service provided by pollinating animals declines. However, most networks... Read More about Constructing more informative plant–pollinator networks: visitation and pollen deposition networks in a heathland plant community.

Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing (2015)
Journal Article
Javaheri, B., Carriero, A., Staines, K. A., Chang, Y.-M., Houston, D. A., Oldknow, K. J., Millan, J. L., Kazeruni, B. N., Salmon, P., Shefelbine, S., Farquharson, C., & Pitsillides, A. A. (2015). Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. Bone, 81, 277-291. https://doi.org/10.1016/j.bone.2015.07.035

PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalaci... Read More about Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.

Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart (2015)
Journal Article
Wilson, K. S., Baily, J., Tucker, C. S., Matrone, G., Vass, S., Moran, C., Chapman, K. E., Mullins, J. J., Kenyon, C., Hadoke, P. W. F., & Denvir, M. A. (2015). Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart. Molecular and Cellular Endocrinology, 414, 120-131. https://doi.org/10.1016/j.mce.2015.07.025

Background

Transient early-life perturbations in glucocorticoids (GC) are linked with cardiovascular disease risk in later life. Here the impact of early life manipulations of GC on adult heart structure, function and gene expression were assessed... Read More about Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart.

Impact of Glucocorticoid Induced Reprogramming on Functional, Histological and Molecular Signalling in the Adult Zebrafish Heart (2015)
Presentation / Conference Contribution
Wilson, K., Baily, J., Tucker, C., Vass, S., Moran, C., Chapman, K., Mullins, J., Kenyon, C., Hadoke, P., & Denvir, M. Impact of Glucocorticoid Induced Reprogramming on Functional, Histological and Molecular Signalling in the Adult Zebrafish Heart

Introduction Foetal over-exposure to glucocorticoids (GC) has been associated with cardiovascular disorder in later life however the impact of transient early life alterations in GC activity on the heart itself has not been widely studied. We explore... Read More about Impact of Glucocorticoid Induced Reprogramming on Functional, Histological and Molecular Signalling in the Adult Zebrafish Heart.

The influence of age and cardiorespiratory fitness on circulating angiogenic T cells and CXCR4 expression (2015)
Presentation / Conference Contribution
Ross, M. D., Malone, E. M., Simpson, R. J., & Florida-James, G. (2015, May). The influence of age and cardiorespiratory fitness on circulating angiogenic T cells and CXCR4 expression. Presented at Annual Congress of the American College of Sports Medicine (ACSM)

Aging is associated with endothelial dysfunction, reduced angiogenic capabilities, and an increase in arterial stiffness. Additionally, regular exercise is known to offset the age-related decline in blood vessel number and function. Circulating angio... Read More about The influence of age and cardiorespiratory fitness on circulating angiogenic T cells and CXCR4 expression.

MMP and TIMP temporal gene expression during osteocytogenesis (2015)
Journal Article
Prideaux, M., Staines, K. A., Jones, E. R., Riley, G. P., Pitsillides, A. A., & Farquharson, C. (2015). MMP and TIMP temporal gene expression during osteocytogenesis. Gene Expression Patterns, 18(1-2), 29-36. https://doi.org/10.1016/j.gep.2015.04.004

Osteocytes within bone differentiate from osteoblast precursors which reside in a mineralised extracellular matrix (ECM). Fully differentiated osteocytes are critical for bone development and function but the factors that regulate this differentiatio... Read More about MMP and TIMP temporal gene expression during osteocytogenesis.

Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1: SOCS2 REGULATION OF GH INDUCED GROWTH (2015)
Journal Article
Dobie, R., Ahmed, S. F., Staines, K. A., Pass, C., Jasim, S., MacRae, V. E., & Farquharson, C. (2015). Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1: SOCS2 REGULATION OF GH INDUCED GROWTH. Journal of Cellular Physiology, 230(11), 2796-2806. https://doi.org/10.1002/jcp.25006

Growth hormone (GH) signaling is essential for postnatal linear bone growth, but the relative importance of GHs actions on the liver and/or growth plate cartilage remains unclear. The importance of liver derived insulin like-growth factor-1 (IGF-1) f... Read More about Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1: SOCS2 REGULATION OF GH INDUCED GROWTH.

Ross and Wilson: Anatomy and phsysiology: colouring and workbook. (4th edition) (2014)
Book
Waugh, A., & Grant, A. (2014). Ross and Wilson: Anatomy and phsysiology: colouring and workbook. (4th edition). Churchill Livingstone

Based on the best-selling textbook, Ross and Wilson: Anatomy and Physiology in Health and Illness, 12th edition, this Colouring and Workbook is the number one choice for students whose healthcare courses include the study of anatomy and physiology. T... Read More about Ross and Wilson: Anatomy and phsysiology: colouring and workbook. (4th edition).

The local effects of ovarian diathermy in an ovine model of Polycystic Ovary Syndrome (2014)
Journal Article
Shen, W., Connolly, F., Rae, M. T., Butler, M., Klibanov, A. L., Sboros, V., McNeilly, A. S., & Duncan, W. C. (2014). The local effects of ovarian diathermy in an ovine model of Polycystic Ovary Syndrome. PLOS ONE, 9, Article e111280. https://doi.org/10.1371/journal.pone.0111280

In order to develop a medical alternative to surgical ovarian diathermy (OD) in polycystic ovary syndrome (PCOS) more mechanistic information is required about OD. We therefore studied the cellular, molecular and vascular effects of diathermy on the... Read More about The local effects of ovarian diathermy in an ovine model of Polycystic Ovary Syndrome.

Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Inhibitor Sml1 in Response to Iron Deficiency (2014)
Journal Article
Sanvisens, N., Romero, A. M., An, X., Zhang, C., de Llanos, R., Martinez-Pastor, M. T., Bañó, M. C., Huang, M., & Puig, S. (2014). Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Inhibitor Sml1 in Response to Iron Deficiency. Molecular and Cellular Biology, 34(17), 3259-3271. https://doi.org/10.1128/mcb.00472-14

Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox-active cofactor in many biological processes, including DNA replication and repair. Eukaryotic ribonucleotide reductases (RNRs) are Fe-dependent enzyme... Read More about Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Inhibitor Sml1 in Response to Iron Deficiency.

Diurnal variation in physiological, psychological and immune responses to running 10 km time trials performed in hot and cold environments (2014)
Thesis
Boukelia, B. Diurnal variation in physiological, psychological and immune responses to running 10 km time trials performed in hot and cold environments. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/9162

Purpose: To investigate the physiological, immunological and psychological response to an intense bout of exercise performed by highly trained individuals at 09:00 hs and 16:00 hs (Chapter 5) and at 09:00 hs and 18:00 hs (Chapter 6). Methods: Using a... Read More about Diurnal variation in physiological, psychological and immune responses to running 10 km time trials performed in hot and cold environments.

Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. (2013)
Journal Article
Szemes, M., Davies, R. L., Garden, C. L. P., & Usowicz, M. M. (2013). Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. Molecular Brain, 6, 33

BACKGROUND

Down's syndrome (DS) is caused by triplication of all or part of human chromosome 21 and is characterized by a decrease in the overall size of the brain. One of the brain regions most affected is the cerebellum, in which the number of g... Read More about Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome..

A holidic medium for Drosophila melanogaster (2013)
Journal Article
Piper, M. D. W., Blanc, E., Leitão-Gonçalves, R., Yang, M., He, X., Linford, N. J., Hoddinott, M. P., Hopfen, C., Soultoukis, G. A., Niemeyer, C., Kerr, F., Pletcher, S. D., Ribeiro, C., & Partridge, L. (2014). A holidic medium for Drosophila melanogaster. Nature methods, 11(1), 100-105. https://doi.org/10.1038/nmeth.2731

A critical requirement for research using model organisms is a well-defined and consistent diet. There is currently no complete chemically defined (holidic) diet available for Drosophila melanogaster. We describe a holidic medium that is equal in per... Read More about A holidic medium for Drosophila melanogaster.

miRNA-221 and miRNA-222 synergistically function to promote vascular calcification: MIR221/222 PROMOTE VASCULAR CALCIFICATION (2013)
Journal Article
Mackenzie, N. C. W., Staines, K. A., Zhu, D., Genever, P., & MacRae, V. E. (2014). miRNA-221 and miRNA-222 synergistically function to promote vascular calcification: MIR221/222 PROMOTE VASCULAR CALCIFICATION. Cell Biochemistry and Function, 32(2), 209-216. https://doi.org/10.1002/cbf.3005

Vascular calcification shares many similarities with skeletal mineralisation and involves the phenotypic trans-differentiation of vascular smooth muscle cells (VSMCs) to osteoblastic cells within a calcified environment. Various microRNAs (miRs) are... Read More about miRNA-221 and miRNA-222 synergistically function to promote vascular calcification: MIR221/222 PROMOTE VASCULAR CALCIFICATION.

Differential effect of transient global ischaemia on the levels of GABA(A) receptor subunit mRNAs in young and older rats. (2012)
Journal Article
Montori, S., Dos Anjos, S., Poole, A. V., Regueiro-Purrinos, M. M., Llorente, I. L., Darlison, M. G., Fernandez-Lopez, A., & Martínez-Villayandre, B. (2012). Differential effect of transient global ischaemia on the levels of GABA(A) receptor subunit mRNAs in young and older rats. Neuropathology and Applied Neurobiology, 38, 710-722. https://doi.org/10.1111/j.1365-2990.2012.01254.x

Aims: This study has investigated how global brain ischaemia/reperfusion (I/R) modifies levels of mRNAs encoding GABA(A) receptor alpha1, beta2 and gamma2 subunits and glutamic acid decarboxylase 65 (GAD65) in an age- and structure-dependent manner.... Read More about Differential effect of transient global ischaemia on the levels of GABA(A) receptor subunit mRNAs in young and older rats..

Ross and Wilson : Anatomy and phsyiology in health and illness. (11th edition Polish ) (2012)
Book
Waugh, A., & Grant, A. (2012). Ross and Wilson : Anatomy and phsyiology in health and illness. (11th edition Polish ). Elsevier Urban Partner

Ross and Wilson has been the number one choice for over a million students since it first published, over 50 years ago. One of the worlds most popular textbooks of anatomy and physiology, it introduces the structure and functions of the human body an... Read More about Ross and Wilson : Anatomy and phsyiology in health and illness. (11th edition Polish ).