An investigation of cell wall micropore blocking as a possible mechanism for the decay resistance of anhydride modified wood (2005)
Journal Article
Hill, C. A. S., Forster, S. C., Farahani, M. R. M., Hale, M. D. C., Ormondroyd, G. A., & Williams, G. R. (2005). An investigation of cell wall micropore blocking as a possible mechanism for the decay resistance of anhydride modified wood. International biodeterioration & biodegradation, 55(1), 69-76. https://doi.org/10.1016/j.ibiod.2004.07.003

Corsican pine (Pinus nigra) sapwood was chemically modified with acetic, or hexanoic anhydride to a variety of weight percentage gains. The cell wall microporosity of the wood before and after chemical modification was determined using the technique... Read More about An investigation of cell wall micropore blocking as a possible mechanism for the decay resistance of anhydride modified wood.

Photosynthetic responses to Cu2+ exposure are independent of light acclimation and uncoupled from growth inhibition in Fucus serratus (Phaeophyceae). (2005)
Journal Article
Nielsen, H. D., & Nielsen, S. L. (2005). Photosynthetic responses to Cu2+ exposure are independent of light acclimation and uncoupled from growth inhibition in Fucus serratus (Phaeophyceae). Marine Pollution Bulletin, 51(8-12), 715-721. https://doi.org/10.1016/j.marpolbul.2005.02.016

We have studied the effect of light acclimation on photosynthetic responses and growth during Cu2+ exposure (0–0.84 μM) in the brown seaweed Fucus serratus. Measurements of chlorophyll fluorescence parameters showed that Cu2+ exposure amplified ETR,... Read More about Photosynthetic responses to Cu2+ exposure are independent of light acclimation and uncoupled from growth inhibition in Fucus serratus (Phaeophyceae)..

Generation of “Neoheparin” from E. coli K5 Capsular Polysaccharide (2004)
Journal Article
Lindahl, U., Li, J.-P., Kusche-Gullberg, M., Salmivirta, M., Alaranta, S., Veromaa, T., Emeis, J., Roberts, I., Taylor, C., Oreste, P., Zoppetti, G., Naggi, A., Torri, G., & Casu, B. (2005). Generation of “Neoheparin” from E. coli K5 Capsular Polysaccharide. Journal of Medicinal Chemistry, 48(2), 349-352. https://doi.org/10.1021/jm049812m

Heparin remains a major drug in prevention of thromboembolic disease. Concerns related to its animal source have prompted search for heparin analogues. The anticoagulant activity of heparin depends on a specific pentasaccharide sequence that binds a... Read More about Generation of “Neoheparin” from E. coli K5 Capsular Polysaccharide.

Antiinflammatory Steroid Action in Human Ovarian Surface Epithelial Cells (2004)
Journal Article
Hillier, S. G., Rae, M. T., Niven, D., Critchley, H. O. D., & Harlow, C. R. (2004). Antiinflammatory Steroid Action in Human Ovarian Surface Epithelial Cells. Journal of Clinical Endocrinology and Metabolism, 89(9), 4538-4544. https://doi.org/10.1210/jc.2003-032225

The human ovarian surface epithelium (OSE) is subject to
serial injury and repair during ovulation, which is a natural inflammatory event. We asked whether there is a compensatory antiinflammatory component to this process, involving steroid hormone... Read More about Antiinflammatory Steroid Action in Human Ovarian Surface Epithelial Cells.

Anthracene derivatives as anti-cancer agents. (2004)
Patent
Mincher, D., & Turnbull, A. (2004). Anthracene derivatives as anti-cancer agents

The present invention relates to compounds which are based on an anthraquinone nucleus for use in medicine, particularly as anti-cancer agents which exert their effects through their interaction with the activity of topoisomerases. The inhibition of... Read More about Anthracene derivatives as anti-cancer agents..

The Structure of Escherichia coli ATP-phosphoribosyltransferase: Identification of Substrate Binding Sites and Mode of AMP Inhibition (2003)
Journal Article
Lohkamp, B., McDermott, G., Campbell, S. A., Coggins, J. R., & Lapthorn, A. J. (2004). The Structure of Escherichia coli ATP-phosphoribosyltransferase: Identification of Substrate Binding Sites and Mode of AMP Inhibition. Journal of Molecular Biology, 336(1), 131-144. https://doi.org/10.1016/j.jmb.2003.12.020

ATP-phosphoribosyltransferase (ATP-PRT), the first enzyme of the histidine pathway, is a complex allosterically regulated enzyme, which controls the flow of intermediates through this biosynthetic pathway. The crystal structures of Escherichia coli A... Read More about The Structure of Escherichia coli ATP-phosphoribosyltransferase: Identification of Substrate Binding Sites and Mode of AMP Inhibition.

Cellular responses of developing Fucus serratus embryos exposed to elevated concentrations of Cu2+. (2003)
Journal Article
Nielsen, H. D., Brown, M. T., & Brownlee, C. (2003). Cellular responses of developing Fucus serratus embryos exposed to elevated concentrations of Cu2+. Plant, Cell and Environment, 26(10), 1737-1747. https://doi.org/10.1046/j.1365-3040.2003.01091.x

Elevated concentrations of Cu2+ can have inhibitory effects on early development in plants and algae by targeting specific cellular processes. In the present study the effects of elevated Cu2+ on developmental processes in embryos of the brown algae... Read More about Cellular responses of developing Fucus serratus embryos exposed to elevated concentrations of Cu2+..

Expression of pro-inflammatory proteins in the lung epithelial cell line A549, in response to cytokine, and environmental particle exposure. (2003)
Thesis
Ramage, L. environmental particle exposure. (Thesis). Napier University. http://researchrepository.napier.ac.uk/id/eprint/2778

This thesis investigates the effects of various inflammatory stimuli, including cytokines and air pollution particles, on the expression and secretion of various proinflammatory proteins in the lung epithelial cell line A549. The pro-inflammatory pro... Read More about Expression of pro-inflammatory proteins in the lung epithelial cell line A549, in response to cytokine, and environmental particle exposure..

Inter-population differences in inherited copper tolerance involve photosynthetic adaptation and exclusion mechanisms in Fucus serratus. (2003)
Journal Article
Nielsen, H. D., Brownlee, C., Coelho, S. M., & Brown, M. T. (2003). Inter-population differences in inherited copper tolerance involve photosynthetic adaptation and exclusion mechanisms in Fucus serratus. New Phytologist, 160(1), 157-165. https://doi.org/10.1046/j.1469-8137.2003.00864.x

• A comparative study of copper (Cu) toxicity and tolerance in three populations of Fucus serratus was conducted by examining Cu2+ effects on various physiological parameters.

• Chlorophyll fluorescence, oxygen evolution, copper content, and rela... Read More about Inter-population differences in inherited copper tolerance involve photosynthetic adaptation and exclusion mechanisms in Fucus serratus..

Stereospecific synthesis of chiral caprolactone monomers from D-glucose. (2003)
Journal Article
Defossemont, G., & Mincher, D. (2003). Stereospecific synthesis of chiral caprolactone monomers from D-glucose. Carbohydrate Research, 338(6), 563-565. https://doi.org/10.1016/S0008-6215%2802%2900490-1

The synthesis and characterisation of a novel chiral bicyclic oxacaprolactone is reported. The choice of diisopropylidene- -glucose as a starting material allowed selective introduction of the synthetic equivalent necessary for the formation of the s... Read More about Stereospecific synthesis of chiral caprolactone monomers from D-glucose..

Molecular toxicology studies on the quartz hazard. (2003)
Thesis
Duffin, R. Molecular toxicology studies on the quartz hazard. (Thesis). Napier University. http://researchrepository.napier.ac.uk/id/eprint/2777

Silicon makes up almost 28% of the Earth's crust and within that crust, quartz (crystalline silica) is one of the most abundant minerals. Exposure to quartz can occur
in a number of occupations, including the mining and construction industries in wh... Read More about Molecular toxicology studies on the quartz hazard..

Relationships between mechanical properties, weight loss and chemical composition of wood during incipient brown rot decay. (2002)
Journal Article
Curling, S., Clausen, C. A., & Winandy, J. E. (2002). Relationships between mechanical properties, weight loss and chemical composition of wood during incipient brown rot decay. Forest Products Journal, 52, 34-39

Incipient decay of wood by brown-rot fungi causes measurable strength losses in wood before measurable weight loss occurs. Previous studies have shown that the high levels of strength loss that occur during incipient brown-rot decay may be related to... Read More about Relationships between mechanical properties, weight loss and chemical composition of wood during incipient brown rot decay..

Experimental method to quantify progressive stages of decay of wood by basidiomycete fungi. (2002)
Journal Article
Curling, S. F., Clausen, C. A., Winandy, J. E., & Curling, S. (2002). Experimental method to quantify progressive stages of decay of wood by basidiomycete fungi. International Biodeterioration and Biodegradation, 49(1), 13-19. https://doi.org/10.1016/S0964-8305%2801%2900101-9

A biological exposure method was developed that allows wood samples to be progressively removed for monitoring colonization and decay by basidiomycete fungi. Monitoring involves strength tests, determination of weight loss, and chemical analysis. To... Read More about Experimental method to quantify progressive stages of decay of wood by basidiomycete fungi..

A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge (2002)
Journal Article
de la Sota, A., Aspichueta, E., Dalzell, D., Dalzell, D., Alte, S., Aspichueta, E., De la Sota, A., Etxebarria, J., Gutierrez, M., Hoffmann, C., Sales, D., Obst, U., & Christofi, N. (2002). A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge. Chemosphere, 47(5), 535-545. https://doi.org/10.1016/s0045-6535%2801%2900331-9

Five rapid direct toxicity assessment methods were used in three European partner countries to determine the toxicity of single toxicants, mixed toxicants and real industrial wastes. The final aim was to protect microbial degradation of organic waste... Read More about A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge.

Anandamide induces cardiorespiratory reflexes via vasosensory nerves in the anaesthetized rat. (2001)
Journal Article
Smith, P. J. W., Smith, P., & McQueen, D. S. (2001). Anandamide induces cardiorespiratory reflexes via vasosensory nerves in the anaesthetized rat. British Journal of Pharmacology, 134(3), 655-663. https://doi.org/10.1038/sj.bjp.0704296

We tested the hypothesis that sensory nerves innervating blood vessels play a role in the local and systemic regulation of the cardiovascular and respiratory (CVR) systems. We measured CVR reflexes evoked by administration of anandamide (86 – 863 nmo... Read More about Anandamide induces cardiorespiratory reflexes via vasosensory nerves in the anaesthetized rat..

Seasonal variations in nutrient levels in Bemersyde Moss, Borders Region, Scotland. (2001)
Journal Article
Velander, K., & Mocogni, M. (2001). Seasonal variations in nutrient levels in Bemersyde Moss, Borders Region, Scotland. The naturalist, 126, 17-26

Nutrient levels were monitored over a twelve month period in Bemersyde Moss, a shallow wetland in southern Scotland. The Moss is used by a variety of waterfowl, both as a winter roost by approximately 100-250 greylag geese (Anser anser) and in summer... Read More about Seasonal variations in nutrient levels in Bemersyde Moss, Borders Region, Scotland..

Agricultural and avian nutrient input into a shallow wetland, Bemersyde Moss, Roxburghshire, Scotland (2001)
Journal Article
Velander, K., & Mocogni, M. (2001). Agricultural and avian nutrient input into a shallow wetland, Bemersyde Moss, Roxburghshire, Scotland. The naturalist, 126, 17-26

Choice of spectroscopic line shape model affects metabolite peak areas and area ratios. (2000)
Journal Article
Marshall, I., Bruce, S. D., Higinbotham, J., MacLullich, A., Wardlaw, J. M., Ferguson, K. J., & Seckl, J. (2000). Choice of spectroscopic line shape model affects metabolite peak areas and area ratios. Magnetic Resonance in Medicine, 44, 646-649. https://doi.org/10.1002/1522-2594%28200010%2944%3A43.0.CO%3B2-0

The use of Lorentzian model lineshapes leads to systematic errors in the quantification of in vivo (1)H NMR spectra. Experimental lineshapes are better modeled by the Voigt (mixed Lorentzian-Gaussian) function, leading to more accurate fits (reduced... Read More about Choice of spectroscopic line shape model affects metabolite peak areas and area ratios..

Chemoinformatics in Microbiology: Identifying Phathogenic Microbes (2000)
Presentation / Conference Contribution
Soufian, M., & Claydon, M. (2000, December). Chemoinformatics in Microbiology: Identifying Phathogenic Microbes. Presented at BIO- and CHEMO- INFORMATICS

No abstract available.

An analytical derivation of a popular approximation of the Voigt function for quantification of NMR spectra. (2000)
Journal Article
Bruce, S. D., Higinbotham, J., Marshall, I., & Beswick, P. H. (2000). An analytical derivation of a popular approximation of the Voigt function for quantification of NMR spectra. Journal of magnetic resonance, 142(1), 57-63. https://doi.org/10.1006/jmre.1999.1911

The approximation of the Voigt line shape by the linear summation of Lorentzian and Gaussian line shapes of equal width is well documented and has proved to be a useful function for modeling in vivo (1)H NMR spectra. We show that the error in determi... Read More about An analytical derivation of a popular approximation of the Voigt function for quantification of NMR spectra..