Abnormal breathing patterns in stroke: relationship with location of acute stroke lesion and prior cerebrosvascular disease. (2006)
Journal Article
Rowat, A. M., Wardlaw, J. M., & Dennis, M. S. (2006). Abnormal breathing patterns in stroke: relationship with location of acute stroke lesion and prior cerebrosvascular disease. Journal of Neurology, Neurosurgery and Psychiatry, 78, 277-279. https://doi.org/10.1136/jnnp.2006.102228

Objective: To determine whether central periodic breathing (CPB) is associated with acute involvement of any particular part of the brain, or the extent of total damage in patients with acute stroke.

Methods: CPB was identified using portable mon... Read More about Abnormal breathing patterns in stroke: relationship with location of acute stroke lesion and prior cerebrosvascular disease..

Gender differences and mental health: An exploratory study of knowledge and attitudes to mental health among Scottish teenagers (2006)
Journal Article
Williams, B., & Pow, J. (2007). Gender differences and mental health: An exploratory study of knowledge and attitudes to mental health among Scottish teenagers. Child and Adolescent Mental Health, 12(1), 8-12. https://doi.org/10.1111/j.1475-3588.2006.00413.x

Method:  A cross-sectional survey of 496 teenagers was conducted in order to explore their knowledge and attitude towards mental health and people with mental health problems.

Results:  Boys reported lower levels of knowledge and different sources... Read More about Gender differences and mental health: An exploratory study of knowledge and attitudes to mental health among Scottish teenagers.

Predicting treatment outcome on three measures for post-traumatic stress disorder (2006)
Journal Article
Karatzias, A., Power, K., McGoldrick, T., Brown, K., Buchanan, R., Sharp, D., & Swanson, V. (2007). Predicting treatment outcome on three measures for post-traumatic stress disorder. European Archives of Psychiatry and Clinical Neuroscience, 257(1), 40-46. https://doi.org/10.1007/s00406-006-0682-2

The aim of the present study was to investigate predictors of treatment outcome for Posttraumatic Stress Disorder (PTSD) after treatment completion and at 15-months follow-up (n = 48), in a trial of Eye Movement Desensitisation and Reprocessing (EMDR... Read More about Predicting treatment outcome on three measures for post-traumatic stress disorder.

Perfusion Imaging with Single Photon Emission Computed Tomography (2006)
Book Chapter
Dougall, N., & Ebmeier, K. (2006). Perfusion Imaging with Single Photon Emission Computed Tomography. In D. Perani, C. Morris, & K. Herholz (Eds.), The Dementias: early diagnosis and evaluation (197-228). Taylor & Francis. https://doi.org/10.3109/9781420016819.007

PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3 (2006)
Journal Article
Kerr, F., Rickle, A., Nayeem, N., Brandner, S., Cowburn, R. F., & Lovestone, S. (2006). PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3. FEBS Letters, 580(13), 3121-3128. https://doi.org/10.1016/j.febslet.2006.04.064

Deregulation of PTEN/Akt signalling has been recently implicated in the pathogenesis of Alzheimer's disease (AD), but the effects on the molecular processes underlying AD pathology have not yet been fully described. Here we report that overexpression... Read More about PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3.

Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice (2006)
Journal Article
Brown, M., & Marshall, K. (2006). Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice. Journal of Psychiatric and Mental Health Nursing, 13(2), 234-241. https://doi.org/10.1111/j.1365-2850.2006.00947.x

People with learning disabilities are an ageing and increasing population and have been the subject of policy initiatives by the four countries of the UK, detailing the range of supports that need to be in place for this group. The evidence base of t... Read More about Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice.

Sgβ1, a novel locust (Schistocerca gregaria) non-α nicotinic acetylcholine receptor-like subunit with homology to the Drosophila melanogaster Dβ1 subunit (2005)
Journal Article
Jones, A. K., Marshall, J., Blake, A. D., Buckingham, S. D., Darlison, M. G., & Sattelle, D. B. (2005). Sgβ1, a novel locust (Schistocerca gregaria) non-α nicotinic acetylcholine receptor-like subunit with homology to the Drosophila melanogaster Dβ1 subunit. Invertebrate Neuroscience, 5(3-4), 147-155. https://doi.org/10.1007/s10158-005-0007-6

The cloning, sequencing and functional expression of Sgβ1, a novel locust (Schistocerca gregaria) non-α nicotinic acetylcholine receptor (nAChR) subunit is described. This subunit shows 80% identity with the Drosophila melanogaster Dβ1 and 92% identi... Read More about Sgβ1, a novel locust (Schistocerca gregaria) non-α nicotinic acetylcholine receptor-like subunit with homology to the Drosophila melanogaster Dβ1 subunit.

Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: A meta-analysis (2005)
Journal Article
Arroll, B., Macgillivray, S., Ogston, S., Reid, I., Sullivan, F., Williams, B., & Crombie, I. (2005). Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: A meta-analysis. Annals of Family Medicine, 3(5), 449-456. https://doi.org/10.1370/afm.349

PURPOSE Depression is common in primary care. There are no systematic reviews of depression treatment comparing antidepressants with placebo; hence, we do not know whether these medications are effective in primary care.

METHODS We searched the Co... Read More about Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: A meta-analysis.

Functional Imaging (2005)
Book Chapter
Ebmeier, K. P., Sutherland, J. K., & Dougall, N. J. (2005). Functional Imaging. In D. Ames, A. Burns, & J. O'Brien (Eds.), Dementia (94-103). (3rd). CRC Press. https://doi.org/10.1201/b13239-13

Global cognitive impairment should be taken into account in SPECT–neuropsychology correlations: the example of verbal memory in very mild Alzheimer’s disease. (2005)
Journal Article
Rodriguez, G., Morbelli, S., Brugnolo, A., Calvini, P., Girtler, N., Piccardo, A., Dougall, N., Ebmeier, K. P., Baron, J. C., & Nobili, F. (2005). Global cognitive impairment should be taken into account in SPECT–neuropsychology correlations: the example of verbal memory in very mild Alzheimer’s disease. European Journal of Nuclear Medicine and Molecular Imaging, 32(10), 1186-1192. https://doi.org/10.1007/s00259-005-1831-y

Purpose: To examine the impact of severity of global cognitive impairment on SPECT-neuropsychology correlations, we correlated a verbal memory test with brain perfusion in patients with very mild Alzheimer's disease (AD), taking into account the Mini... Read More about Global cognitive impairment should be taken into account in SPECT–neuropsychology correlations: the example of verbal memory in very mild Alzheimer’s disease..

Bipolar Affective Disorder - A national clinical guideline (2005)
Report
Ebmeier, K., Baig, B., Brown, A., Cavanagh, J., Clark, S., Davidson, K., Dougall, N., Fraser, K., Lawton, K., Mitchell, F., Nightingale, A., Power, M., Reid, I., Service, D., Shawcross, M., Topalian, J., Wade, A., & Wilson, L. (2005). Bipolar Affective Disorder - A national clinical guideline. Edinburgh: Scottish Intercollegiate Guidelines Network (SIGN)

A national clinical guideline - SIGN.

Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties (2005)
Journal Article
Hand, P. J., Wardlaw, J. M., Rowat, A. M., Haisma, J. A., Lindley, R. I., & Dennis, M. S. (2005). Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties. Journal of Neurology, Neurosurgery and Psychiatry, 76, 1525-1527. https://doi.org/10.1136/jnnp.2005.062539

Objectives: To assess organisational and patient specific limitations and safety of magnetic resonance
imaging (MRI) as the first line investigation for hospital admitted stroke patients.
Methods: Consecutive patients admitted with acute stroke wer... Read More about Magnetic resonance brain imaging in patients with acute stroke: feasibility and patient related difficulties.

The chicken immediate-early gene ZENK is expressed in the medio-rostral neostriatum/hyperstriatum ventrale, a brain region involved in acoustic imprinting, and is up-regulated after exposure to an auditory stimulus (2004)
Journal Article
Thode, C., Bock, J., Braun, K., & Darlison, M. (2005). The chicken immediate-early gene ZENK is expressed in the medio-rostral neostriatum/hyperstriatum ventrale, a brain region involved in acoustic imprinting, and is up-regulated after exposure to an auditory stimulus. Neuroscience, 130(3), 611-617. https://doi.org/10.1016/j.neuroscience.2004.10.015

The immediate-early gene zenk (an acronym for the avian orthologue of the mammalian genes zif-268, egr-1, ngfi-a and krox-24) has been extensively employed, in studies on oscine birds, as a marker of neuronal activity to reveal forebrain structures t... Read More about The chicken immediate-early gene ZENK is expressed in the medio-rostral neostriatum/hyperstriatum ventrale, a brain region involved in acoustic imprinting, and is up-regulated after exposure to an auditory stimulus.

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease (2004)
Journal Article
Hye, A., Kerr, F., Archer, N., Foy, C., Poppe, M., Brown, R., Hamilton, G., Powell, J., Anderton, B., & Lovestone, S. (2004). Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters, 373(1), 1-4. https://doi.org/10.1016/j.neulet.2004.10.031

Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease modifying treatment. As increasing evidence has suggested a role for glycogen synthase kinase-3 (GSK-3) in the pathogenesis of the condition we measu... Read More about Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease.

Brain Behaviour Relationships in Dementia (Neuropsychology) (2003)
Book Chapter
Sutherland, J., Dougall, N., & Ebmeier, K. (2003). Brain Behaviour Relationships in Dementia (Neuropsychology). In SPECT in Dementia; Advances in Biological Psychiatry (38-50). Karger Publishers. https://doi.org/10.1159/000073164

Voxel-Based Approaches in Clinical Imaging (2003)
Book Chapter
Ebmeier, K., Darcourt, J., Dougall, N., Glabus, M., Herholz, K., Koulibaly, P., Migneco, O., Pupi, A., Nobili, F., Robert, P., Rodriguez, G., & Scheidhauer, K. (2003). Voxel-Based Approaches in Clinical Imaging. In SPECT in Dementia; Advances in Biological Psychiatry (72-85). Karger Publishers. https://doi.org/10.1159/000073167

Voxel-Based Approaches in Clinical Imaging.

Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: Systematic review and meta-analysis (2003)
Journal Article
MacGillivray, S., Arroll, B., Hatcher, S., Ogston, S., Reid, I., Sullivan, F., Williams, B., & Crombie, I. (2003). Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: Systematic review and meta-analysis. BMJ, 326, 1014-1017. https://doi.org/10.1136/bmj.326.7397.1014

Objective: To compare the efficacy and tolerability of tricyclic antidepressants with selective serotonin reuptake inhibitors in depression in primary care.

Design: Systematic review and meta-analysis of randomised controlled trials.

Data sourc... Read More about Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: Systematic review and meta-analysis.

The Clinical Use of 99mTc-HMPAO-SPECT in Alzheimer´s Disease (2003)
Book Chapter
Dougall, N., Bruggink, S., & Ebmeier, K. (2003). The Clinical Use of 99mTc-HMPAO-SPECT in Alzheimer´s Disease. In SPECT in Dementia (4-37). Karger Publishers. https://doi.org/10.1159/000073163

Statistical parametric mapping of 99mTc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake. (2002)
Journal Article
Soonawala, D., Amin, T., Ebmeier, K. P., Steele, J. D., Dougall, N. J., Best, J., Migneco, O., Nobili, F., & Scheidhauer, K. (2002). Statistical parametric mapping of 99mTc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake. NeuroImage, 17(3), 1193-1202. https://doi.org/10.1006/nimg.2002.1259

Background: for a quantitative comparison of images obtained during 99mTc-hexamethylpropylene amine oxime (HMPAO) single-photon emission computed tomography (SPECT), brain activity values are usually normalized to a reference region. In studies of Al... Read More about Statistical parametric mapping of 99mTc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake..

A controlled comparison of eye movement desensitization and reprocessing versus exposure plus cognitive restructuring versus waiting list in the treatment of post-traumatic stress disorder. (2002)
Journal Article
Power, K., McGoldrick, T., Brown, K., Buchanan, R., Sharp, D., Swanson, V., & Karatzias, T. (2002). A controlled comparison of eye movement desensitization and reprocessing versus exposure plus cognitive restructuring versus waiting list in the treatment of post-traumatic stress disorder. Clinical Psychology and Psychotherapy, 9, 299-318. https://doi.org/10.1002/cpp.341

A total of 105 patients with post-traumatic stress disorder (PTSD) were randomly allocated to eye-movement desensitization and reprocessing (EMDR) (n = 39) versus exposure plus cognitive restructuring (E + CR) (n = 37) versus waiting list (WL) (n = 2... Read More about A controlled comparison of eye movement desensitization and reprocessing versus exposure plus cognitive restructuring versus waiting list in the treatment of post-traumatic stress disorder..