Immunomodulatory effects of cannabinoids in human T-lymphocytes (2009)
Presentation / Conference Contribution
Schinwald, A., Galban-Horcajo, F., Malone, E., & Smith, P. (2009, December). Immunomodulatory effects of cannabinoids in human T-lymphocytes. Presented at British Pharmacology Society Winter Meeting 2009

Background: Circulating levels of endocannabinoids are elevated in obese and hyperglycaemic patients and may contribute to immune dysfunction in obesity and diabetes. Cannabinoids have been shown to evoke both pro-and anti-inflammatory responses, act... Read More about Immunomodulatory effects of cannabinoids in human T-lymphocytes.

Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death: DAPK and signal transduction (2009)
Journal Article
Lin, Y., Hupp, T. R., & Stevens, C. (2010). Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death: DAPK and signal transduction. FEBS Journal, 277(1), 48-57. https://doi.org/10.1111/j.1742-4658.2009.07411.x

Death-associated protein kinase (DAPK) is a stress-regulated protein
kinase that mediates a range of processes, including signal-induced cell death and autophagy. Although the kinase domain of DAPK has a range of substrates that mediate its signalli... Read More about Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death: DAPK and signal transduction.

Autophagy: from basic science to clinical application (2009)
Journal Article
Van Limbergen, J., Stevens, C., Nimmo, E. R., Wilson, D. C., & Satsangi, J. (2009). Autophagy: from basic science to clinical application. Mucosal immunology, 2(4), 315-330. https://doi.org/10.1038/mi.2009.20

Autophagy is a cellular pathway involved in protein and organelle degradation, which is likely to represent an innate adaptation to starvation. In times of nutrient deficiency, the cell can self-digest and recycle some nonessential components through... Read More about Autophagy: from basic science to clinical application.

NuMA is required for proper spindle assembly and chromosome alignment in prometaphase (2009)
Journal Article
Haren, L., Gnadt, N., Wright, M., & Merdes, A. (2009). NuMA is required for proper spindle assembly and chromosome alignment in prometaphase. BMC Research Notes, 2, Article 64. https://doi.org/10.1186/1756-0500-2-64

NuMA is a protein that has been previously shown to play a role in focusing microtubules at the mitotic spindle poles. However, most previous work relies on experimental methods that might cause dominant side effects on spindle formation, such as mic... Read More about NuMA is required for proper spindle assembly and chromosome alignment in prometaphase.