Ross and Wilson : Anatomy and physiology in health and illness. (10th edition French) (2007)
Book
Waugh, A., & Grant, A. (2007). Ross and Wilson : Anatomy and physiology in health and illness. (10th edition French). Elsevier Paris/Churchill Livingstone

Ross and Wilson has been the number one choice for over a million students since it first published, over 50 years ago. One of the world's most popular textbooks of anatomy and physiology, it introduces the structure and functions of the human body a... Read More about Ross and Wilson : Anatomy and physiology in health and illness. (10th edition French).

Ross and Wilson : Anatomy and physiology in health and illness. (10th edition Dutch) (2007)
Book
Waugh, A., & Grant, A. (2007). Ross and Wilson : Anatomy and physiology in health and illness. (10th edition Dutch). Elsevier-Churchill Livingstone

Ross and Wilson has been the number one choice for over a million students since it first published, over 50 years ago. One of the worlds most popular textbooks of anatomy and physiology, it introduces the structure and functions of the human body an... Read More about Ross and Wilson : Anatomy and physiology in health and illness. (10th edition Dutch).

Expression of Cannabinoid CB1 receptors in models of diabetic neuropathy (2007)
Journal Article
Zhang, F., Hong, S., Stone, V., & Smith, P. (2007). Expression of Cannabinoid CB1 receptors in models of diabetic neuropathy. Journal of Pharmacology and Experimental Therapeutics, 323, 508-515. https://doi.org/10.1124/jpet.107.128272

A clearer understanding of the mechanisms underlying the development and progression of diabetic neuropathy is likely to indicate new directions for the treatment of this complication of diabetes. In the present study we investigated the expression o... Read More about Expression of Cannabinoid CB1 receptors in models of diabetic neuropathy.

Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise (2007)
Journal Article
Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G. D., & Simpson, R. J. (2008). Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain, Behavior, and Immunity, 22(3), 375-380. https://doi.org/10.1016/j.bbi.2007.09.001

Cytotoxic T-lymphocytes co-express the T-cell receptor, CD3 and the MHC I restricted antigen CD8. Although total CD8 expression is often used to identify CD8+ T-cells in blood, errors are associated with this method as some CD3 negative natural kille... Read More about Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise.

Carbohydrate-gel supplementation and endurance performance during intermittent high-intensity shuttle running (2007)
Journal Article
Patterson, S. D., & Gray, S. (2007). Carbohydrate-gel supplementation and endurance performance during intermittent high-intensity shuttle running. International Journal of Sport Nutrition and Exercise Metabolism, 17,

The aim of this study was to investigate the effects of a carbohydrate (CHO) gel on performance after prolonged intermittent high-intensity shuttle running. Seven male soccer players performed 2 exercise trials, 7 d apart. On each occasion, participa... Read More about Carbohydrate-gel supplementation and endurance performance during intermittent high-intensity shuttle running.

Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure (2007)
Journal Article
Barlow, P. G., Brown, D. M., Donaldson, K., MacCallum, J., & Stone, V. (2008). Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure. Cell Biology and Toxicology, 24(3), 243-252. https://doi.org/10.1007/s10565-007-9033-y

Increased levels of particulate air pollution (PM10) have been implicated as a causal agent in pulmonary disease exacerbation and increased deaths from respiratory and cardiovascular disorders. The exact mechanism by which PM10 drives toxicity in the... Read More about Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure.

Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation (2007)
Journal Article
Marshall, H. C., Campbell, S. A., Roberts, C. W., & Nimmo, M. A. (2007). Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation. Journal of Thermal Biology, 32(6), 341-348. https://doi.org/10.1016/j.jtherbio.2007.04.003

1. The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined.

2. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P

An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. (2007)
Journal Article
Brown, D. M., Kinloch, I. A., Bangert, U., Windle, A., Walter, D. M., Walker, G. S., Scotchford, C. A., Donaldson, K., & Stone, V. (2007). An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis. Carbon, 45, 1743-1756. https://doi.org/10.1016/j.carbon.2007.05.011

There has been little information to date based on the potential health effects and hazards associated with the inhalation of carbon nanofibrous materials by workers despite their growing use in industry. This study examines the in vitro effects of a... Read More about An in vitro study of the potential of carbon nanotubes and nanofibres to induce inflammatory mediators and frustrated phagocytosis..

Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Black, J., Ross, J., & Guy, K. (2007). Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. Research in Sports Medicine, 15, 157-174. https://doi.org/10.1080/15438620701405339

The lymphocytopenia that occurs during the recovery stage of exercise may be a result of apoptosis through an increased expression of CD95, a loss of the complement regulatory proteins CD55 and CD59, or both. Trained subjects completed intensive, mod... Read More about Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans..

Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling. (2007)
Journal Article
Nevill, A. M., Jobson, S. A., Davison, R., & Jeukendrup, A. E. (2007). Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling. European Journal of Applied Physiology, 97, 424-431. https://doi.org/10.1007/s00421-006-0189-6

The purpose of this article was to establish whether previously reported oxygen-to-mass ratios, used to predict flat and hill-climbing cycling performance, extend to similar power-to-mass ratios incorporating other, often quick and convenient measure... Read More about Optimal power-to-mass ratios when predicting flat and hill-climbing time-trial cycling..

Role of androgens in fetal testis development and dysgenesis. (2007)
Journal Article
Scott, H. M., Hutchison, G. R., Mahood, I. K., Hallmark, N., Welsh, M., De Gendt, K., Verhoeven, G., Shaugnessy, P., & Sharpe, R. M. (2007). Role of androgens in fetal testis development and dysgenesis. Endocrinology, 148, 2027-2036. https://doi.org/10.1210/en.2006-1622

This study sought to establish whether reduced androgen levels/action in the fetal rat testis induced by di(n-butyl) phthalate (DBP) contributes to dysgenetic features, namely reduced Sertoli cell number, occurrence of multinucleated gonocytes (MNG),... Read More about Role of androgens in fetal testis development and dysgenesis..

The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists. (2007)
Journal Article
Brown, D. M., Hutchison, L., Donaldson, K., & Stone, V. (2007). The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists. American journal of physiology. Lung cellular and molecular physiology, 292, L1444-L1451. https://doi.org/10.1152/ajplung.00162.2006

We have previously examined the ability of air pollution particles (PM10) to promote release of the proinflammatory cytokine tumor necrosis factor- (TNF-) from human peripheral blood mononuclear cells and demonstrated a role for calcium as a signalin... Read More about The effects of PM10 particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists..

High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H., & Guy, K. (2007). High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. Journal of Applied Physiology, 103, 396-401. https://doi.org/10.1152/japplphysiol.00007.2007

Clonal expansion of T lymphocytes in response to antigenic stimulation is a fundamental process of adaptive immunity. As a consequence of clonal expansion, some T lymphocytes acquire a senescent phenotype, fail to replicate in response to further ant... Read More about High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects..

Effect of instrument attachment on the surface temperature of juvenile grey seals (Halichoerus Grypus) measured by infrared thermography. (2007)
Journal Article
McCafferty, D. J., Currie, J., & Sparling, C. E. (2007). Effect of instrument attachment on the surface temperature of juvenile grey seals (Halichoerus Grypus) measured by infrared thermography. Deep Sea Research Part II Topical Studies in Oceanography, 54, 424-436. https://doi.org/10.1016/j.dsr2.2006.11.019

Previous research has highlighted the importance of minimising hydrodynamic drag from biologging instruments fitted to marine mammals. However, there is a need to investigate other possible impacts of instruments on animals. The aim of this study was... Read More about Effect of instrument attachment on the surface temperature of juvenile grey seals (Halichoerus Grypus) measured by infrared thermography..

Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. (2007)
Journal Article
Lin, Y., Stevens, C., & Hupp, T. (2007). Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. Journal of Biological Chemistry, 282(23), 16792-16802. https://doi.org/10.1074/jbc.M611559200

DAPK-1 is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. To define mechanisms of DAPK-1 protein regulation, we have determined that DAPK-1 protein has a long half-life... Read More about Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis..

Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity (2007)
Journal Article
Fraser, J. A., & Hupp, T. R. (2007). Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity. Biochemistry, 46(10), 2655-2673. https://doi.org/10.1021/bi061562j

Dissection of signal transduction pathways has been advanced by classic genetic approaches including targeted gene deletion and siRNA-based inhibition of gene product synthesis. Chemical genetics is a biochemical approach to develop small peptide-mim... Read More about Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity.

The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4 (2007)
Journal Article
Brown, D. M., Hutchison, L., Donaldson, K., MacKenzie, S., Dick, C., & Stone, V. (2007). The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. https://doi.org/10.1016/j.toxlet.2006.10.016

Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transcription factors such as nuclear factor kappa B (NF-κB) and AP-1 have been s... Read More about The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4.

The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Middleton, N., Shave, R., George, K., & Guy, K. (2007). The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. European Journal of Applied Physiology, 99, 201-204. https://doi.org/10.1007/s00421-006-0326-2

Exercise is known to result in the haemolysis of red blood cells (RBCs). Although mechanical stressors such as footstrike and an increased velocity of blood flow may be involved, the biological mechanisms that underpin RBC haemolysis remain elusive.... Read More about The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells..

Thyroid hormone signaling in human ovarian surface epithelial cells. (2007)
Journal Article
Rae, M. T., Gubbay, O., NaKostogiannou, A., Price, D., Critchley, H. O. D., & Hillier, S. G. (2007). Thyroid hormone signaling in human ovarian surface epithelial cells. Journal of Clinical Endocrinology and Metabolism, 92, 322-327. https://doi.org/10.1210/jc.2006-1522

Ovarian surface epithelial (OSE) cells express multiple nuclear hormone receptor genes, including those encoding thyroid hormone and estrogen receptors (TR and ER, respectively). Ovarian cancer is hormone-dependent, and epidemiological evidence links... Read More about Thyroid hormone signaling in human ovarian surface epithelial cells..

Impact of repeated prolonged exercise bouts on cardiac function and biomarkers. (2007)
Journal Article
Middleton, N., Shave, R., George, K., Whyte, G. P., Simpson, R. J., Florida-James, G., & Gaze, D. (2007). Impact of repeated prolonged exercise bouts on cardiac function and biomarkers. Medicine and Science in Sports and Exercise, 39, 83-90. https://doi.org/10.1249/01.mss.0000239395.93578.60

Purpose: The present study examined the impact of repeated bouts of prolonged (< 60 min) exercise on left ventricular function and cardiac biomarkers.

Methods: Ten athletes completed a 15.3-mile hill run on three consecutive days and were assessed... Read More about Impact of repeated prolonged exercise bouts on cardiac function and biomarkers..