An investigation of commonly used IBD drugs on autophagy pathway activity and potential therapeutic benefit for the treatment of paediatric IBD Sep 1, 2014 - Aug 31, 2017
Recent genetic discoveries, principally identification of NOD2 and ATG16L1 as susceptibility loci, strongly implicate a dysregulated host response to enteric bacteria and the autophagy pathway in the pathogenesis of Crohn’s disease (CD). Several micr... Read More about An investigation of commonly used IBD drugs on autophagy pathway activity and potential therapeutic benefit for the treatment of paediatric IBD.

Cathelicidins as novel therapeutic antiviral agents in Rhinovirus infection May 1, 2015 - Jun 30, 2017
We have identified the human cathelicidn LL-37 as having potent direct antiviral activity against human rhinovirus (HRV), together with the capacity to alter death pathways in HRV-infected cells, as a potential host defence mechanism. We propose to c... Read More about Cathelicidins as novel therapeutic antiviral agents in Rhinovirus infection.

Students into Work Jun 1, 2014 - Oct 31, 2014
Salmonella enterica is a leading cause of foodborne infection with a recent increase in the number of antibiotic resistant isolates. We propose a biotechnological approach to the development of novel antimicrobial prodrug therapy which exploits the S... Read More about Students into Work.

Investigation of STM3071 function in Salmonella May 26, 2015 - Aug 31, 2015
Students into Work Vacation Studentship 2015

Beltane Public Engagement Fellowships Jan 5, 2015 - Aug 19, 2015
To embed Public Engagement (PE) as a core part of good teaching, learning, research and knowledge exchange.To support staff and students to become confident practitioners in PE by development of a network and support infrastructure.To showcase and re... Read More about Beltane Public Engagement Fellowships.

An examination of current attitudes towards the threat of Schmallenberg virus Oct 1, 2013 - Jun 10, 2014
The aim of this research is to evaluate the current attitude of the farming community in Scotland to the threat of Schmallenberg virus and the willingness to carry out vaccination by way of a questionnaire. This information will then be used to raise... Read More about An examination of current attitudes towards the threat of Schmallenberg virus.

The Antiviral activities of the cationic host defence peptide LL-37 against Rhinovirus Feb 1, 2013 - Nov 12, 2014
A pump-priming proposal designed to investigate the potential for LL-37, a human cationic host defence peptide, to inhibit Rhinovirus infection and/or target cells infected with Rhinovirus for induction of apoptotic cell death

Acceptability of extragenital Chlamydia testing Sep 1, 2017 - Apr 30, 2018
Chlamydia trachomatis is the most common sexually transmitted infection in Scotland, and has significant long‐term consequences to reproductive health. Recent studies suggest that in addition to the genital tract, Chlamydia is found in the throat and... Read More about Acceptability of extragenital Chlamydia testing.

Novel insights, tools and measures to mitigate emerging risks by yeasts in the food chain Aug 1, 2017 - Jul 31, 2018
The main goal of this project is to understand the mechanisms responsible for the virulence of food-related yeasts on humans, and to provide tools and recommendations to prevent the release of yeasts strains that pose a risk to the population into th... Read More about Novel insights, tools and measures to mitigate emerging risks by yeasts in the food chain.

MinION sequencing of bacterial isolates May 22, 2017 - Jul 31, 2020
MinION sequencing of bacterial isolates

IBD drug effect on autophagy (IDEA) Oct 1, 2017 - Mar 31, 2018
An investigation of commonly used IBD drugs on autophagy pathway activity and potential therapeutic benefit for treatment of paediatric IBD

Bacteriophage endolysins and novel lipid-degrading proteins as a treatment for Rhodococcus equi infections in foals Oct 1, 2018 - Dec 31, 2019
Rhodococcus equi (Req) is responsible for severe respiratory disease of foals with a major economic impact on the equine industry, and can be endemic on stud farms. In foals under 6 months of age, this bacterial disease manifests as pneumonia, with 3... Read More about Bacteriophage endolysins and novel lipid-degrading proteins as a treatment for Rhodococcus equi infections in foals.

Mechanism of Chlamydia induced progesterone resistance Apr 1, 2018 - Jul 31, 2019
Chlamydia trachomatis is the most common sexually-transmitted infection in the world, and is associated with miscarriage, pre-term birth and infertility. However, the understanding of the mechanisms through which infection leads to pregnancy failure... Read More about Mechanism of Chlamydia induced progesterone resistance.

Development of a UV-C hand-sanitiser unit Nov 1, 2017 - Dec 22, 2017
Development of a UV-C hand-sanitiser unit

The influence of ultramarathon running event on immune and cardiovascular systems Oct 1, 2017 - Sep 30, 2018
The project will measure circulating white blood cells and progenitor cells in response to an extreme exercise running bout/event/ We will also be quantifying upper respiratory tract symptoms.

Rutherford fund Strategic Partner Grant Sep 1, 2018 - Mar 31, 2019
Rutherford Fellows, will work in project areas related to food safety (Pathogen detection, AMR etc) and food spoilage.

Rutherford Fund, are funded by BEIS and the scheme is being managed by Universities UK International

Ranking novel immune-modulating therapeutics for progression to clinical development Jul 2, 2018 - Sep 30, 2019
Ranking novel immune-modulating therapeutics for progression to clinical development

TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector. Apr 1, 2018 - Oct 21, 2019
TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.

The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients Oct 1, 2018 - Sep 30, 2021
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James and is investigating the effect of exercise on che... Read More about The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients.

Direct and paracrine effects of Chlamydia infection on decidualisation of endometrial stromal cells Jun 1, 2018 - Aug 31, 2018
SRF summer studentship