Dr Craig Stevens C.Stevens@napier.ac.uk
Associate Professor
Cathelicidins as novel therapeutic antiviral agents in Rhinovirus infection
People Involved
Prof Peter Barlow P.Barlow@napier.ac.uk
Professor
Project Description
We have identified the human cathelicidn LL-37 as having potent direct antiviral activity against human rhinovirus (HRV), together with the capacity to alter death pathways in HRV-infected cells, as a potential host defence mechanism. We propose to characterise the mechanism by which LL-37 exerts antiviral effects towards HRV, and to access the potential for both exogenous LL-37 and Vitamin D to be used as antiviral therapeutics in this infection.
| Status | Project Complete |
|---|---|
| Funder(s) | Chief Scientists Office |
| Value | £163,152.00 |
| Project Dates | May 1, 2015 - Jun 30, 2017 |
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