Prediction of in-hospital mortality and length of stay using an early warning scoring system: clinical audit (2006)
Journal Article
Paterson, R., MacLeod, D., Thetford, D., Beattie, A., Graham, C., Lam, S., & Bell, D. (2006). Prediction of in-hospital mortality and length of stay using an early warning scoring system: clinical audit. Clinical Medicine, 6(3), 281-284. https://doi.org/10.7861/clinmedicine.6-3-281

This aim of this study was to assess the impact of the introduction of a standardised early warning scoring system (SEWS) on physiological observations and patient outcomes in unselected acute admissions at point of entry to care. A sequential clinic... Read More about Prediction of in-hospital mortality and length of stay using an early warning scoring system: clinical audit.

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. (2005)
Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005). Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933

Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main determinant of parasite survival. In a laboratory model of infection, using... Read More about Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo..

The influence of particle composition and size on in vitro and in vivo biological models. (2003)
Report
Lightbody, J., Hutchison, G. R., Donaldson, K., & Stone, V. (2003). The influence of particle composition and size on in vitro and in vivo biological models

Particulate air pollution has been consistently linked with an increase in morbidity and mortality due to respiratory complications and cardiovascular disease. The aim of this study was to investigate which components of PM10 are important in driving... Read More about The influence of particle composition and size on in vitro and in vivo biological models..

A preliminary evaluation of the differences in the glycosylation of alpha-1-acid glycoprotein between individual liver diseases. (2002)
Journal Article
Anderson, N. E., Pollacchi, A., Hayes, P., Therapondos, G., Newsome, P., Boyter, A., & Smith, K. (2002). A preliminary evaluation of the differences in the glycosylation of alpha-1-acid glycoprotein between individual liver diseases. Biomedical Chromatography, 16, 365-372. https://doi.org/10.1002/bmc.167

During the acute phase response (APR) to tissue injury or infection, the liver is responsible for the level of mediators such as cytokines required at the site of inflammation and providing the essential components for wound healing and tissue repair... Read More about A preliminary evaluation of the differences in the glycosylation of alpha-1-acid glycoprotein between individual liver diseases..

Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia (1994)
Journal Article
MacLeod, K. M., Hepburn, D. A., Deary, I. J., Goodwin, G. M., Dougall, N., Ebmeier, K. P., & Frier, B. M. (1994). Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia. Diabetologia, 37(3), 257-263. https://doi.org/10.1007/s001250050103

Chronic hyperglycaemia and recurrent severe hypoglycaemia have both been implicated as causing cerebral damage in patients with diabetes. Although cognitive dysfunction and intellectual impairment have been demonstrated in patients with recurrent sev... Read More about Regional cerebral blood flow in IDDM patients: effects of diabetes and of recurrent severe hypoglycaemia.

State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment (1993)
Journal Article
Goodwin, G. M., Austin, M.-P., Dougall, N., Ross, M., Murray, C., O'Caroll, R. E., Moffoot, A., Prentice, N., & Ebmeier, K. P. (1993). State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment. Journal of Affective Disorders, 29(4), 243-253. https://doi.org/10.1016/0165-0327%2893%2990014-b

Twenty-eight patients with a major depressive episode previously investigated at rest using Single Photon Emission Tomography (SPET or SPECT) with 99mTc-exametazime, were followed up at an interval of 9–28 months with the same investigation after ful... Read More about State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment.

The effect of anxiety induction on the regional uptake of 99mTc-Exametazime in simple phobia as shown by single photon emission tomography (SPET) (1993)
Journal Article
O'Carroll, R. E., Moffoot, A. P. R., Van Beck, M., Dougall, N., Murray, C., Ebmeier, K. P., & Goodwin, G. M. (1993). The effect of anxiety induction on the regional uptake of 99mTc-Exametazime in simple phobia as shown by single photon emission tomography (SPET). Journal of Affective Disorders, 28(3), 203-210. https://doi.org/10.1016/0165-0327%2893%2990106-t

Ten patients suffering from DSM-III-R simple phobia were studied under two conditions: (a) while listening to a 4 min relaxation tape, and (b) while listening to a 4 min audio tape describing exposure to the phobic stimulus. During each condition, su... Read More about The effect of anxiety induction on the regional uptake of 99mTc-Exametazime in simple phobia as shown by single photon emission tomography (SPET).

Single-photon emission computed tomography with 99mTc-exametazime in unmediated schizophrenic patients (1993)
Journal Article
Ebmeier, K. P., Blackwood, D. H. R., Murray, C., Souza, V., Walker, M., Dougall, N., Moffoot, A. P. R., O'Carroll, R. E., & Goodwin, G. M. (1993). Single-photon emission computed tomography with 99mTc-exametazime in unmediated schizophrenic patients. Biological Psychiatry, 33(7), 487-495. https://doi.org/10.1016/0006-3223%2893%2990002-u

We examined 20 actively psychotic unmedicated schizophrenic patients and 20 matched control subjects by using single-photon emission, computed tomography (SPECT) with 99mtechnetium-exametazime. Patients showed a hyperfrontal pattern of tracer uptake... Read More about Single-photon emission computed tomography with 99mTc-exametazime in unmediated schizophrenic patients.

Unilateral voluntary hand movement and regional cerebral uptake of technetium-99m-exametazime in human control subjects (1992)
Journal Article
Dougall, N. (1992). Unilateral voluntary hand movement and regional cerebral uptake of technetium-99m-exametazime in human control subjects. Journal of Nuclear Medicine, 33(9), 1623-1627

Regional cerebral blood flow and cognitive function in patients with chronic liver disease (1991)
Journal Article
O'Carroll, R. E., Ebmeier, K. P., Dougall, N., Murray, C., Goodwin, G. M., Hayes, P. C., Bouchier, I. A. D., & Best, J. J. K. (1991). Regional cerebral blood flow and cognitive function in patients with chronic liver disease. Lancet, 337(8752), 1250-1253. https://doi.org/10.1016/0140-6736%2891%2992920-w

Subtle impairments of cognitive function may be an important cause of occupational and psychosocial morbidity in patients with chronic liver disease. Correlation of structural brain abnormalities with cognitive deficits has yielded inconsistent resul... Read More about Regional cerebral blood flow and cognitive function in patients with chronic liver disease.