Skip to main content

Research Repository

Advanced Search

A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA (2012)
Journal Article
Nguyen, H. V., Zhao, Z.-Y., Sallustrau, A., Horswell, S. L., Male, L., Mulas, A., & Tucker, J. H. R. (2012). A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA. Chemical Communications, 48, 12165. https://doi.org/10.1039/C2CC36428J

The design, synthesis and electrochemical behaviour of an oligomer consisting of linked thymine-functionalised ferrocene units are reported, which, as a so-called form of ferrocene nucleic acid (FcNA), acts as a structural mimic of DNA.

Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device (2012)
Thesis
O'Connor, L. Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/5260

The main piece of legislation which addresses illicit drugs in the UK is the Misuse of Drugs Act 1971. The Act was designed to prevent the use of drugs which are 'capable of having harmful effects sufficient to constitute a social problem'.
The Roa... Read More about Development of a method for the detection of GHB and other drugs using a handheld Raman Spectroscopy device.

Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824 (2012)
Thesis
Almohaish, A. A. Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/5692

In low GC Gram-positive bacteria, the phenomenon of carbon catabolite repression is dependent on a metabolite-activated bifunctional protein kinase/phosphorylase. In Clostridium acetobutylicum ATCC 824, the hprK gene encodes the bifunctional protein... Read More about Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824.

Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe (2012)
Journal Article
Zhao, Z.-Y., San, M., Duprey, J.-L. H. A., Arrand, J. R., Vyle, J. S., & Tucker, J. H. R. (2012). Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe. Bioorganic and Medicinal Chemistry Letters, 22(1), 129-132. https://doi.org/10.1016/j.bmcl.2011.11.053

Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing internal anthracene fluorophores proximal to the SNP site. Depending upon the nature of the... Read More about Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe.