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A qualitative study exploring the views, attitudes and beliefs of patients and health professionals towards exercise intervention for people who are surgically treated for lung cancer (2018)
Journal Article
Crandall, K., Maguire, R., Campbell, A., & Kearney, N. (2018). A qualitative study exploring the views, attitudes and beliefs of patients and health professionals towards exercise intervention for people who are surgically treated for lung cancer. European Journal of Cancer Care, 27(2), e12828. https://doi.org/10.1111/ecc.12828

Surgical removal remains the best curative option for patients diagnosed with early‐stage lung cancer. However, it is also associated with significant morbidity and reduced quality of life. Interventions to improve patient outcomes are required. This... Read More about A qualitative study exploring the views, attitudes and beliefs of patients and health professionals towards exercise intervention for people who are surgically treated for lung cancer.

Design and evaluation of novel fluorogenic probes and prodrugs in cancer. (2017)
Thesis
Mather, S. Design and evaluation of novel fluorogenic probes and prodrugs in cancer. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/1034936

Despite major advances in the diagnosis and treatment of cancer, there remains a paucity of biomarkers for early detection (poor selectivity and specificity). Legumain [asparaginyl endopeptidase (AEP); EC 3.4.22.34] is a potential cancer biomarker an... Read More about Design and evaluation of novel fluorogenic probes and prodrugs in cancer..

Design and synthesis of novel prodrugs to modulate GABA receptors in cancer (2017)
Thesis
Zhang, H. Design and synthesis of novel prodrugs to modulate GABA receptors in cancer. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/Output/978678

GABA (gamma-amino butanoic acid) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA has been found to play an inhibitory role in some cancers, including colon carcinoma, cholangiocarcinoma, and lung adenocarcinoma.... Read More about Design and synthesis of novel prodrugs to modulate GABA receptors in cancer.

Recruitment to the “Breast—Activity and Healthy Eating After Diagnosis” (B-AHEAD) Randomized Controlled Trial (2017)
Journal Article
Pegington, M., Adams, J. E., Bundred, N. J., Harvie, M. N., Campbell, A., Howell, A., Howell, S. J., Speed, S., Wolstenholme, J., & Harvey, M. (2018). Recruitment to the “Breast—Activity and Healthy Eating After Diagnosis” (B-AHEAD) Randomized Controlled Trial. Integrative Cancer Therapies, 17(1), 131-137. https://doi.org/10.1177/1534735416687850

Excess weight at breast cancer diagnosis and weight gain during treatment are linked to increased breast cancer specific and all-cause mortality. The Breast—Activity and Healthy Eating After Diagnosis (B-AHEAD) trial tested 2 weight loss diet and exe... Read More about Recruitment to the “Breast—Activity and Healthy Eating After Diagnosis” (B-AHEAD) Randomized Controlled Trial.

Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer (2016)
Presentation / Conference Contribution
Mathur, S., Mincher, D., Turnbull, A., Stevens, C., & Poole, A. Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer

Background: In spite of major advances in the diagnosis and treatment of cancer, there remains a paucity of biomarkers for early detection. Legumain is a potential cancer biomarker and a molecular target for imaging and drug targeting. Legumain is a... Read More about Design and evaluation of novel theranostic fluorogenic dual probe-prodrug in cancer.

Physical activity and cancer: movement matters. (2015)
Presentation / Conference Contribution
Campbell, A. (2015, December). Physical activity and cancer: movement matters. Presented at Living with and beyond cancer: a masterclass for primary care

Experiences of recruiting to a pilot trial of Cardiac Rehabilitation In patients with Bowel cancer (CRIB) with an embedded process evaluation: lessons learned to improve recruitment (2015)
Journal Article
Hubbard, G., Campbell, A., Davies, Z., Munro, J., Ireland, A. V., Leslie, S., Watson, A. J. M., & Treweek, S. (2015). Experiences of recruiting to a pilot trial of Cardiac Rehabilitation In patients with Bowel cancer (CRIB) with an embedded process evaluation: lessons learned to improve recruitment. Pilot and Feasibility Studies, 1(1), https://doi.org/10.1186/s40814-015-0009-z

Background
Recruitment to randomised controlled trials (RCTs) is a perennial problem. Calls have been made for trialists to make recruitment performance publicly available. This article presents our experience of recruiting to a pilot RCT of cardiac... Read More about Experiences of recruiting to a pilot trial of Cardiac Rehabilitation In patients with Bowel cancer (CRIB) with an embedded process evaluation: lessons learned to improve recruitment.

Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship (2015)
Journal Article
Christensen, J. F., Bandak, M., Campbell, A., Jones, L. W., & Højman, P. (2015). Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta oncologica, 54(5), 592-599. https://doi.org/10.3109/0284186x.2014.995776

Treatment of testicular germ cell cancer constitutes a major success story in modern oncology. Today, the vast majority of patients are cured by a therapeutic strategy using one or more highly effective components including surgery (orchiectomy), rad... Read More about Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship.

Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up (2014)
Journal Article
Trinh, L., Mutrie, N., Campbell, A. M., Crawford, J. J., & Courneya, K. S. (2014). Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up. European Journal of Oncology Nursing, 18(6), 557-563. https://doi.org/10.1016/j.ejon.2014.07.004

Short-term physical activity (PA) has beneficial effects on symptom management and quality of life, however, longer-term adherence is likely needed for improved disease outcomes in breast cancer survivors (BCS). This study examined the effects of a s... Read More about Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up.

Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy (2014)
Thesis
Ding, Y. Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy. (Thesis). Edinburgh Napier University. http://researchrepository.napier.ac.uk/id/eprint/7555

Proteolytic degradation of the extracellular matrix (ECM) by overexpressed endoproteases, notably the matrix metalloproteinase MMP-9 and legumain (human asparaginyl endopeptidase), contributes to the invasive and migratory phenotype of cancer cells a... Read More about Design, synthesis and evaluation of novel endoprotease-activated prodrugs and fluorogenic probes with theranostic applications in chemotherapy.

Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review (2014)
Journal Article
Crandall, K., Maguire, R., Campbell, A., & Kearney, N. (2014). Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review. Surgical Oncology, 23(1), 17-30. https://doi.org/10.1016/j.suronc.2014.01.001

AbstractBackground Surgery remains the best curative option for appropriately selected patients with lung cancer. Evidence suggests that improving cardiovascular fitness and functional capacity can accelerate post-surgery recovery and reduce mortalit... Read More about Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review.

Understanding barriers to exercise implementation 5-year post-breast cancer diagnosis: a large-scale qualitative study (2013)
Journal Article
Hefferon, K., Murphy, H., McLeod, J., Mutrie, N., & Campbell, A. (2013). Understanding barriers to exercise implementation 5-year post-breast cancer diagnosis: a large-scale qualitative study. Health Education Research, 28(5), 843-856. https://doi.org/10.1093/her/cyt083

Due to the amount of literature supporting exercise participation after cancer diagnosis, there has been recent interest in barriers to exercise engagement among cancer patients. However, little is known regarding reasons why people choose to disenga... Read More about Understanding barriers to exercise implementation 5-year post-breast cancer diagnosis: a large-scale qualitative study.

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling (2012)
Journal Article
Sandilands, E., Serrels, B., McEwan, D. G., Morton, J. P., Macagno, J. P., McLeod, K., Stevens, C., Brunton, V. G., Langdon, W. Y., Vidal, M., Sansom, O. J., Dikic, I., Wilkinson, S., & Frame, M. C. (2012). Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nature Cell Biology, 14(1), 51-60. https://doi.org/10.1038/ncb2386

Here we describe a mechanism that cancer cells use to survive when flux through the Src/FAK pathway is severely perturbed. Depletion of FAK, detachment of FAK-proficient cells or expression of non-phosphorylatable FAK proteins causes sequestration of... Read More about Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.

P4-12-01: The Breast-Activity and Healthy Eating after Diagnosis (B-AHEAD) Study – A Randomised Comparison of Weight Control Programmes during Adjuvant Treatment. (2011)
Journal Article
Campbell, A., Harvie, M., Pegington, M., Bundred, N., Campbell, A., Wolstenholme, J., Adams, J., Speed, S., Morris, J., & Howell, A. (2011). P4-12-01: The Breast-Activity and Healthy Eating after Diagnosis (B-AHEAD) Study – A Randomised Comparison of Weight Control Programmes during Adjuvant Treatment. Cancer Research, 71(24 Supplement), P4-12-01-P4-12-01. https://doi.org/10.1158/0008-5472.sabcs11-p4-12-01

Abstracts: Thirty-Fourth Annual CTRC-AACR San Antonio Breast Cancer Symposium-- Dec 6-10, 2011; San Antonio, TXBackground: Excess weight at diagnosis and weight gain during treatment are linked to increased mortality from breast cancer. Since 60% of... Read More about P4-12-01: The Breast-Activity and Healthy Eating after Diagnosis (B-AHEAD) Study – A Randomised Comparison of Weight Control Programmes during Adjuvant Treatment..

Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks (2011)
Journal Article
Lowrie, A. G., Dickinson, P., Wheelhouse, N., Stewart, G. D., Ross, A. J., Forster, T., & Ross, J. A. (2011). Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks. International Journal of Oncology, 39(3), 709-18. https://doi.org/10.3892/ijo.2011.1064

Dermcidin is a candidate oncogene capable of increasing the number of cultured neuronal, breast cancer and prostate cancer cells and improving the survival of hepatic cells. The dermcidin gene encodes the proteolysis-inducing factor core pepti... Read More about Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks.

The Cancer Rehabilitation Journey: Barriers to and Facilitators of Exercise Among Patients With Cancer-Related Fatigue (2010)
Journal Article
Blaney, J., Lowe-Strong, A., Rankin, J., Campbell, A., Allen, J., & Gracey, J. (2010). The Cancer Rehabilitation Journey: Barriers to and Facilitators of Exercise Among Patients With Cancer-Related Fatigue. Physical Therapy, 90(8), 1135-1147. https://doi.org/10.2522/ptj.20090278

Background Despite the evidence to support exercise as an effective management strategy for patients with cancer-related fatigue (CRF), many of the general cancer population are sedentary. Objective The aim of this study was to explore the barriers t... Read More about The Cancer Rehabilitation Journey: Barriers to and Facilitators of Exercise Among Patients With Cancer-Related Fatigue.

Physical Activity Levels of Women Attending Glasgow Breast Clinics (2009)
Journal Article
Tan, A., Pavlidou, E., Ogston, K., Doughty, J., Wilson, C., Campbell, A., & Tovey, S. (2009). Physical Activity Levels of Women Attending Glasgow Breast Clinics. Cancer Research, 69(24 Supplement), 2066-2066. https://doi.org/10.1158/0008-5472.sabcs-09-2066

Introduction
Epidemiological studies suggest that moderate intensity recreational physical activity (PA) improves breast cancer survival. We aimed to assess the current levels of PA in breast cancer survivors and a cohort of women with benign diseas... Read More about Physical Activity Levels of Women Attending Glasgow Breast Clinics.