All Outputs (50)

The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy (2021)
Journal Article
Russo, G., Laneri, S., Di Lorenzo, R., Ferrara, L., & Grumetto, L. (2021). The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy. Water Environment Research, 93(10), 1944-1958. https://doi.org/10.1002/wer.1566

Endocrine disrupting chemicals (EDCs) are agents able to exert perturbation toward the endocrine system via a broad array of signalling pathways. Some EDCs are released into the environment as a result of antropogenic activities. Analytical surveilla... Read More about The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy.

Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment (2021)
Journal Article
Akhbarizadeh, R., Russo, G., Rossi, S., Golianova, K., Moore, F., Guida, M., De Falco, M., & Grumetto, L. (2021). Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment. Marine Pollution Bulletin, 166, Article 112241. https://doi.org/10.1016/j.marpolbul.2021.112241

The occurrence of endocrine disrupting chemicals (EDCs) has been determined in two widely consumed fish species from Persian Gulf i.e., Epinephelus coioides and Platycephalus indicus by applying a validated analytical for the simultaneous detection o... Read More about Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment.

Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development (2020)
Journal Article
Russo, G., Grumetto, L., Baert, M., & Lynen, F. (2021). Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development. Analytica Chimica Acta, 1142, 157-168. https://doi.org/10.1016/j.aca.2020.11.003

A comprehensive two-dimensional liquid chromatography-based biomimetic platform (LCxLC) has been developed and validated for drug diffusion studies. Human serum albumin (HSA) and immobilized artificial membrane (IAM) were thereby used in the first (1... Read More about Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development.

Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity (2020)
Journal Article
Russo, G., Ermondi, G., Caron, G., Verzele, D., & Lynen, F. (2021). Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity. European Journal of Pharmaceutical Sciences, 156, 105585. https://doi.org/10.1016/j.ejps.2020.105585

State of the art: Sphingomyelin (SPH) is a type of sphingolipid found in animal nerve tissues, especially in the membranous myelin sheath that surrounds some nerve cell axons. Because of its characteristics, SPH stationary phase represents an ideal t... Read More about Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity.

Coupling of chemical and biological processes in 17alfa-ethinylestradiol removal from aqueous solutions: a critical evaluation of adsorption and catalysis contribution (2019)
Journal Article
Russo, G., Grumetto, L., Mita, D. G., Rossi, S., Guida, M., Di Marco Pisciottano, I., & Gallo, P. (2019). Coupling of chemical and biological processes in 17alfa-ethinylestradiol removal from aqueous solutions: a critical evaluation of adsorption and catalysis contribution. Desalination and Water Treatment, 170, 158-167. https://doi.org/10.5004/dwt.2019.24651

The removal of 17alfa-ethinylestradiol (EE2) from synthetic aqueous solutions under adsorption process and enzyme catalysis mediated by immobilized laccase from Trametes versicolor was studied. Both processes were carried... Read More about Coupling of chemical and biological processes in 17alfa-ethinylestradiol removal from aqueous solutions: a critical evaluation of adsorption and catalysis contribution.

Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection (2019)
Journal Article
Del Prete, S., Marasco, D., Del Prete, A., Meloni, M., Capaldi, R., Grumetto, L., & Russo, G. (2019). Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection. Archives of Case Reports, 3(1), 50-53. https://doi.org/10.29328/journal.acr.1001024

Purpose: This work is aimed at demonstrating that scraping cytology and scanning electron microscopy can successfully assist in the diagnosis of nontuberculous mycobacteria infection. For this purpose, we report the use of both these techniques in th... Read More about Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection.

Are Canned Beverages Industries Progressively Switching to Bisphenol AF? (2019)
Journal Article
Russo, G., Varriale, F., Barbato, F., & Grumetto, L. (2019). Are Canned Beverages Industries Progressively Switching to Bisphenol AF?. Journal of Food Science, 84(11), 3303-3311. https://doi.org/10.1111/1750-3841.14833

Seven bisphenols, endocrine‐disruptor chemicals, were analytically determined for risk assessment in 52 large‐consumption beverages collected from the Italian market. The analytes under examination were bisphenol A, bisphenol F, bisphenol E, bispheno... Read More about Are Canned Beverages Industries Progressively Switching to Bisphenol AF?.

Occurrence of Bisphenol A and its analogues in some foodstuff marketed in Europe (2019)
Journal Article
Russo, G., Barbato, F., Mita, D. G., & Grumetto, L. (2019). Occurrence of Bisphenol A and its analogues in some foodstuff marketed in Europe. Food and Chemical Toxicology, 131, https://doi.org/10.1016/j.fct.2019.110575

Bisphenol A and its analogues belong to the class of endocrine disrupting chemicals, massively employed by industries to produce polycarbonate and epoxy resins, designed to be in direct contact with foodstuffs. Their leaching from the canned packagin... Read More about Occurrence of Bisphenol A and its analogues in some foodstuff marketed in Europe.

Entry of therapeutics into the brain: Influence of exposed polarity calculated in silico and measured in vitro by supercritical fluid chromatography (2019)
Journal Article
Russo, G., Barbato, F., Grumetto, L., Philippe, L., Lynen, F., & Goetz, G. H. (2019). Entry of therapeutics into the brain: Influence of exposed polarity calculated in silico and measured in vitro by supercritical fluid chromatography. International Journal of Pharmaceutics, 560, 294-305. https://doi.org/10.1016/j.ijpharm.2019.02.008

The present work proposes a novel application of EPSA (not an acronym but found to be referred to by many as Exposed Polar Surface Area), a supercritical fluid chromatography (SFC) polarity readout for assisting in the prediction of the extent of dru... Read More about Entry of therapeutics into the brain: Influence of exposed polarity calculated in silico and measured in vitro by supercritical fluid chromatography.

Scrutinizing the interactions between bisphenol analogues and plasma proteins: Insights from biomimetic liquid chromatography, molecular docking simulations and in silico predictions (2019)
Journal Article
Grumetto, L., Barbato, F., & Russo, G. (2019). Scrutinizing the interactions between bisphenol analogues and plasma proteins: Insights from biomimetic liquid chromatography, molecular docking simulations and in silico predictions. Environmental Toxicology and Pharmacology, 68, 148-154. https://doi.org/10.1016/j.etap.2019.02.008

The interactions between human serum albumin (HSA) and α1- acid glycoprotein (AGP), the main plasma proteins binding drugs/xenobiotics, and some endocrine disrupting chemicals (EDCs), such as bisphenol A (BPA) and some of its structural analogues, bi... Read More about Scrutinizing the interactions between bisphenol analogues and plasma proteins: Insights from biomimetic liquid chromatography, molecular docking simulations and in silico predictions.

Simultaneous determination of fifteen multiclass organic pollutants in human saliva and serum by liquid chromatography–tandem ultraviolet/fluorescence detection: A validated method (2018)
Journal Article
Russo, G., Barbato, F., Mita, D. G., & Grumetto, L. (2019). Simultaneous determination of fifteen multiclass organic pollutants in human saliva and serum by liquid chromatography–tandem ultraviolet/fluorescence detection: A validated method. Biomedical Chromatography, 33(3), e4427. https://doi.org/10.1002/bmc.4427

A quick and inexpensive validated method, based on sample treatment by liquid–liquid microextraction followed by liquid chromatography (LC) coupled with ultraviolet tandem fluorescence detection is proposed for the determination of 15 multiclass poll... Read More about Simultaneous determination of fifteen multiclass organic pollutants in human saliva and serum by liquid chromatography–tandem ultraviolet/fluorescence detection: A validated method.

Human exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules (2018)
Journal Article
Marotta, V., Russo, G., Gambardella, C., Grasso, M., La Sala, D., Chiofalo, M. G., D'Anna, R., Puzziello, A., Docimo, G., Masone, S., Barbato, F., Colao, A., Faggiano, A., & Grumetto, L. (2019). Human exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules. Chemosphere, 218, 885-894. https://doi.org/10.1016/j.chemosphere.2018.11.084

Pollutants represent potential threats to the human health, being ubiquitous in the environment and exerting toxicity even at low doses. This study aims at investigating the role of fifteen multiclass organic pollutants, assumed as markers of environ... Read More about Human exposure to bisphenol AF and diethylhexylphthalate increases susceptibility to develop differentiated thyroid cancer in patients with thyroid nodules.

Cytotoxicity of seven bisphenol analogues compared to bisphenol A and relationships with membrane affinity data (2018)
Journal Article
Russo, G., Capuozzo, A., Barbato, F., Irace, C., Santamaria, R., & Grumetto, L. (2018). Cytotoxicity of seven bisphenol analogues compared to bisphenol A and relationships with membrane affinity data. Chemosphere, 201, 432-440. https://doi.org/10.1016/j.chemosphere.2018.03.014

Bisphenol A (BPA) is a chemical used in numerous industrial applications. Due to its well ascertained toxicity as endocrine disruptor, industries have started to replace it with other bisphenols whose alleged greater safety is scarcely supported by l... Read More about Cytotoxicity of seven bisphenol analogues compared to bisphenol A and relationships with membrane affinity data.

Screening therapeutics according to their uptake across the blood-brain barrier: A high throughput method based on immobilized artificial membrane liquid chromatography-diode-array-detection coupled to electrospray-time-of-flight mass spectrometry (2018)
Journal Article
Russo, G., Grumetto, L., Szucs, R., Barbato, F., & Lynen, F. (2018). Screening therapeutics according to their uptake across the blood-brain barrier: A high throughput method based on immobilized artificial membrane liquid chromatography-diode-array-detection coupled to electrospray-time-of-flight mass spectrometry. European Journal of Pharmaceutics and Biopharmaceutics, 127, 72-84. https://doi.org/10.1016/j.ejpb.2018.02.004

The Blood-Brain Barrier (BBB) plays an essential role in protecting the brain tissues against possible injurious substances. In the present work, 79 neutral, basic, acidic and amphoteric structurally unrelated analytes were considered and their chrom... Read More about Screening therapeutics according to their uptake across the blood-brain barrier: A high throughput method based on immobilized artificial membrane liquid chromatography-diode-array-detection coupled to electrospray-time-of-flight mass spectrometry.

Bisphenol A and Bisphenol S release in milk under household conditions from baby bottles marketed in Italy (2017)
Journal Article
Russo, G., Barbato, F., Cardone, E., Fattore, M., Albrizio, S., & Grumetto, L. (2018). Bisphenol A and Bisphenol S release in milk under household conditions from baby bottles marketed in Italy. Journal of Environmental Science and Health, Part B, 53(2), 116-120. https://doi.org/10.1080/03601234.2017.1388662

A simple and sensitive validated analytical method based on liquid chromatography coupled to tandem fluorescence (FD) and ultraviolet (UV) spectrophotometry was applied to monitor the presence of bisphenol A and bisphenol S in plastic baby bottles ma... Read More about Bisphenol A and Bisphenol S release in milk under household conditions from baby bottles marketed in Italy.

Plasma p-cresol lowering effect of sevelamer in non-dialysis CKD patients: evidence from a randomized controlled trial (2017)
Journal Article
Riccio, E., Sabbatini, M., Bruzzese, D., Grumetto, L., Marchetiello, C., Amicone, M., Andreucci, M., Guida, B., Passaretti, D., Russo, G., & Pisani, A. (2018). Plasma p-cresol lowering effect of sevelamer in non-dialysis CKD patients: evidence from a randomized controlled trial. Clinical and Experimental Nephrology, 22(3), 529-538. https://doi.org/10.1007/s10157-017-1504-8

Background The accumulation of p-cresol, a metabolic product of aromatic amino acids generated by intestinal microbiome, increases the cardiovascular risk in chronic kidney disease (CKD) patients. Therefore, therapeutic strategies to reduce plasma p... Read More about Plasma p-cresol lowering effect of sevelamer in non-dialysis CKD patients: evidence from a randomized controlled trial.

Cholesterol affects the interaction between an ionic liquid and phospholipid vesicles. A study by differential scanning calorimetry and nanoplasmonic sensing (2017)
Journal Article
Russo, G., Witos, J., Rantamäki, A. H., & Wiedmer, S. K. (2017). Cholesterol affects the interaction between an ionic liquid and phospholipid vesicles. A study by differential scanning calorimetry and nanoplasmonic sensing. BBA - Biomembranes, 1859(12), 2361-2372. https://doi.org/10.1016/j.bbamem.2017.09.011

The present work aims at studying the interactions between cholesterol-rich phosphatidylcholine-based lipid vesicles and trioctylmethylphosphonium acetate ([P8881][OAc]), a biomass dissolving ionic liquid (IL). The effect of cholesterol was assayed b... Read More about Cholesterol affects the interaction between an ionic liquid and phospholipid vesicles. A study by differential scanning calorimetry and nanoplasmonic sensing.

Improvement of Retinal Function after Administration of an Ophthalmic Gel Containing a New Recombinant form of Superoxide Dismutase (2017)
Journal Article
Grumetto, L., Prete, A. D., Russo, G., Borrelli, A., Del Prete, S., & Mancini, A. (2017). Improvement of Retinal Function after Administration of an Ophthalmic Gel Containing a New Recombinant form of Superoxide Dismutase. IL Journal of Clinical Case Reports, 1(1), 1-5

Two cases of severe age-related eye maculopathy diagnosed in a 73-year-old and a 53-year-old patient are presented. A gel formulation containing a new recombinant form of manganese superoxide dismutase (rMnSOD) was administered to both patients, as c... Read More about Improvement of Retinal Function after Administration of an Ophthalmic Gel Containing a New Recombinant form of Superoxide Dismutase.

Monitoring of bisphenol A and bisphenol S in thermal paper receipts from the Italian market and estimated transdermal human intake: A pilot study (2017)
Journal Article
Russo, G., Barbato, F., & Grumetto, L. (2017). Monitoring of bisphenol A and bisphenol S in thermal paper receipts from the Italian market and estimated transdermal human intake: A pilot study. Science of the Total Environment, 599-600, 68-75. https://doi.org/10.1016/j.scitotenv.2017.04.192

Bisphenol A (BPA), a synthetic xenoestrogen widely used in various industrial fields, can be present, in its un-reacted form, as an additive in thermal paper. BPA is virtually ubiquitous in industrialized societies and humans are exposed to this chem... Read More about Monitoring of bisphenol A and bisphenol S in thermal paper receipts from the Italian market and estimated transdermal human intake: A pilot study.

Determination of in Vitro and in Silico Indexes for the Modeling of Blood–Brain Barrier Partitioning of Drugs via Micellar and Immobilized Artificial Membrane Liquid Chromatography (2017)
Journal Article
Russo, G., Grumetto, L., Szucs, R., Barbato, F., & Lynen, F. (2017). Determination of in Vitro and in Silico Indexes for the Modeling of Blood–Brain Barrier Partitioning of Drugs via Micellar and Immobilized Artificial Membrane Liquid Chromatography. Journal of Medicinal Chemistry, 60(9), 3739-3754. https://doi.org/10.1021/acs.jmedchem.6b01811

In the present work, 79 structurally unrelated analytes were taken into account and their chromatographic retention coefficients, measured by immobilized artificial membrane liquid chromatography (IAM-LC) and by micellar liquid chromatography (MLC) e... Read More about Determination of in Vitro and in Silico Indexes for the Modeling of Blood–Brain Barrier Partitioning of Drugs via Micellar and Immobilized Artificial Membrane Liquid Chromatography.