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Outputs (129)

Regulation of capsule expression (2010)
Book Chapter
Taylor, C., & Roberts, I. S. (2010). Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences, (115-138). Cambridge: Cambridge University Press

No abstract available.

Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting (2006)
Journal Article
Vizard, C. G., Rimmer, D. L., Pless-Mulloli, T., Singleton, I., & Air, V. S. (2006). Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting. Science of the Total Environment, 370(1), 61-69. https://doi.org/10.1016/j.scitotenv.2006.06.006

A study of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) concentrations was undertaken in the vicinity of a municipal solid waste incinerator (MSWI) in Newcastle upon Tyne as a result of concerns raised by local re... Read More about Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting.

Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS) (2007)
Journal Article
Hua, G., Broderick, J., Semple, K. T., Killham, K., & Singleton, I. (2007). Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS). Environmental Pollution, 148(1), 176-181. https://doi.org/10.1016/j.envpol.2006.10.040

Synchronous fluorescence spectroscopy (SFS) was directly applied to rapidly quantify selected polycyclic aromatic hydrocarbons (PAHs: benzo[a]pyrene and pyrene) in aqueous hydroxypropyl-β-cyclodextrin (HPCD) soil extract solutions from a variety of a... Read More about Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS).

Impact of atmospheric ozone-enrichment on quality-related attributes of tomato fruit (2007)
Journal Article
Tzortzakis, N., Borland, A., Singleton, I., & Barnes, J. (2007). Impact of atmospheric ozone-enrichment on quality-related attributes of tomato fruit. Postharvest Biology and Technology, 45(3), 317-325. https://doi.org/10.1016/j.postharvbio.2007.03.004

Tomato fruit (Lycopersicon esculentum L. cv. Carousel) were exposed to ozone concentrations ranging between 0.005 (controls) and 1.0 μmol mol−1 at 13 °C and 95% RH. Quality-related attributes and organoleptic characteristics were examined during and... Read More about Impact of atmospheric ozone-enrichment on quality-related attributes of tomato fruit.

Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce (2007)
Journal Article
Tzortzakis, N., Singleton, I., & Barnes, J. (2007). Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce. Postharvest Biology and Technology, 43(2), 261-270. https://doi.org/10.1016/j.postharvbio.2006.09.005

Tomatoes, strawberries, table grapes and plums were inoculated with Botrytis cinerea (grey mould), transferred to chilled storage (13 °C) and exposed to ‘clean air’ or low-level ozone-enrichment (0.1 μmol mol−1). Ozone-enrichment resulted in a substa... Read More about Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce.

Bacterial Capsules: A Route for Polysaccharide Engineering (2005)
Book Chapter
Roberts, I., & Taylor, C. (2005). Bacterial Capsules: A Route for Polysaccharide Engineering. In Handbook of Carbohydrate Engineering, 479-494. Boca Raton, USA: CRC Press (Taylor and Francis Group). doi:10.1201/9781420027631.ch16

No abstract available.

The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies (1989)
Book Chapter
Darlison, M. G., Barnard, E. A., Bateson, A. N., Glencorse, T. A., Harvey, R. J., Hicks, A. A., Hunt, S. P., Morris, B. J., Vallejo, M., Vreugdenhil, E., & Wisden, W. (1989). The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies. In Molecular Biology of Neuroreceptors and Ion Channels (83-99). Springer. https://doi.org/10.1007/978-3-642-74155-5_7

It is well established that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) mediates many of its effects by binding to the GABAA receptor, which is present on the majority of mammalian brain neurons (Enna, 1983), resulting in the opening o... Read More about The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies.

Molluscan ligand-gated ion-channel receptors (1993)
Book Chapter
Darlison, M. G., Hutton, M. L., & Harvey, R. J. (1993). Molluscan ligand-gated ion-channel receptors. In Comparative Molecular Neurobiology, 48-64. Springer Verlag. https://doi.org/10.1007/978-3-0348-7265-2_3

In this chapter we introduce the reader to the structures of the different types of ligand-gated ion-channel receptor, and the numerous receptor subtypes that have recently been revealed to exist, in both invertebrate and vertebrate species, by the a... Read More about Molluscan ligand-gated ion-channel receptors.

External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment (1993)
Journal Article
Proudfoot, L., Kusel, J. R., Smith, H. V., & Kennedy, M. W. (1993). External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment. Parasitology, 107(05), 559. https://doi.org/10.1017/s0031182000068141

Previous work has shown that the surface of infective larvae of parasitic nematodes will not bind the fluorescent lipid analogue 5-N(octadecanoyl)aminofluorescein (AF18) until after exposure of the parasite to mammalian tissue-culture conditions. In... Read More about External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment.

Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms (1993)
Journal Article
Proudfoot, L., Kusel, J. R., Smith, H. V., Harnett, W., Worms, M. J., & Kennedy, M. W. (1993). Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms. Parasitology, 107(01), 107. https://doi.org/10.1017/s0031182000079464

All mammalian-parasitic stages of a range of nematode species investigated (Brugia pahangi, Acanthocheilonema viteae, Strongyloides ratti, Nippostrongylus brasiliensis, Trichinella spiralis and Ostertagia ostertagi) labelled in a surface-restricted m... Read More about Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms.

A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis (2007)
Journal Article
Stevens, C., Lin, Y., Sanchez, M., Amin, E., Copson, E., White, H., Durston, V., Eccles, D. M., & Hupp, T. (2007). A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis. Journal of Biological Chemistry, 282(18), 13791-13803. https://doi.org/10.1074/jbc.m605649200

p53 is activated genetically by a set of kinases that are components of the calcium calmodulin kinase superfamily, including CHK2, AMP kinase, and DAPK-1. In dissecting the mechanism of DAPK-1 control, a novel mutation (N1347S) was identified in the... Read More about A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis.

Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. (2007)
Journal Article
Lin, Y., Stevens, C., & Hupp, T. (2007). Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. Journal of Biological Chemistry, 282(23), 16792-16802. https://doi.org/10.1074/jbc.M611559200

DAPK-1 is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. To define mechanisms of DAPK-1 protein regulation, we have determined that DAPK-1 protein has a long half-life... Read More about Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis..

Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves (2020)
Journal Article
King, M., López‐García, M., Atedoghu, K. P., Zhang, N., Wilson, A. M., Weterings, M., Hiwar, W., Dancer, S. J., Noakes, C. J., & Fletcher, L. A. (2020). Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves. Indoor Air, 30(5), 993-1004. https://doi.org/10.1111/ina.12682

Bacterial transmission from contaminated surfaces via hand contact plays a critical role in disease spread. However, the fomite‐to‐finger transfer efficiency of microorganisms during multiple sequential surface contacts with and without gloves has no... Read More about Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves.

Environmental Pollution and Restoration: A Role for Bioremediation (2005)
Book Chapter
Philp, J. C., Bamforth, S., Singleton, I., & Atlas, R. M. (2005). Environmental Pollution and Restoration: A Role for Bioremediation. In R. M. Atlas, & J. Philp (Eds.), Bioremediation (1-48). American Society for Microbiology. https://doi.org/10.1128/9781555817596.ch1

With greater understanding of microbial diversity and the development of bioengineering, bioremediation is taking its place as a cost-effective technique in integrated environmental restoration efforts. The major reasons for the control of water and... Read More about Environmental Pollution and Restoration: A Role for Bioremediation.

Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae (1996)
Journal Article
Singleton, I., & Simmons, P. (1996). Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae. Journal of Chemical Technology and Biotechnology, 65(1), 21-28. https://doi.org/10.1002/%28SICI%291097-4660%28199601%2965%3A13.0.CO%3B2-E

Factors affecting silver biosorption by Saccharomyces cerevisiae biomass, obtained as a waste product from industry, were examined. Maximum removal of silver from solution was achieved within 5 min. Increasing the concentration of biomass in experime... Read More about Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae.

Effects of long-term contamination of DDT on soil microflora with special reference to soil algae and algal transformation of DDT (2000)
Journal Article
Megharaj, M., Kantachote, D., Singleton, I., & Naidu, R. (2000). Effects of long-term contamination of DDT on soil microflora with special reference to soil algae and algal transformation of DDT. Environmental Pollution, 109(1), 35-42. https://doi.org/10.1016/s0269-7491%2899%2900231-6

DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane) and its principle metabolites, DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene) and DDD (1,1-dichloro-2,2-bis(p-chlorophenyl)ethane) are widespread environmental contaminants but little informatio... Read More about Effects of long-term contamination of DDT on soil microflora with special reference to soil algae and algal transformation of DDT.