Molluscan ligand-gated ion-channel receptors

Darlison, Mark G.; Hutton, Michael L.; Harvey, Robert J.

Abstract

In this chapter we introduce the reader to the structures of the different types of ligand-gated ion-channel receptor, and the numerous receptor subtypes that have recently been revealed to exist, in both invertebrate and vertebrate species, by the application of molecular biological methods. We then review some of the data in support of the existence, in molluscs, of such receptor/channel complexes for γ-aminobutyric acid, glutamate and acetylcholine. Finally, recent results from our laboratory on the cloning and expression of complementary DNAs, from the pond-snail Lymnaea stagnalis, that encode GABAA and glutamate receptor subunits will be described.

Citation

Darlison, M. G., Hutton, M. L., & Harvey, R. J. (1993). Molluscan ligand-gated ion-channel receptors. In Comparative Molecular Neurobiology (48-64). Springer. https://doi.org/10.1007/978-3-0348-7265-2_3

• Acceptance Date: Jan 1, 1993
• Publication Date: 1993
• Deposit Date: Aug 1, 2016
• Publisher: Springer
• Pages: 48-64
• Book Title: Comparative Molecular Neurobiology
• ISBN: 9783034872676; 9783034872652
• DOI: https://doi.org/10.1007/978-3-0348-7265-2_3
• Keywords: 5HT3 Receptor, Receptor Subunit, Nicotinic Acetylcholine Receptor, Glycine Receptor, Chloride current,
• Public URL: http://researchrepository.napier.ac.uk/Output/320980