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All Outputs (17)

Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression (1994)
Journal Article
Coon, H., Hicks, A. A., Bailey, M. E., Hoff, M., Holik, J., Harvey, R. J., …Byerley, W. (1994). Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression. Psychiatric Genetics, 4(3), 185-191. https://doi.org/10.1097/00041444-

The gamma-aminobutyric acid (GABA) neurotransmitter system has been implicated in the pathogenesis of manic depression. Tests of this hypothesis can now be carried out due to the recent characterization of simple sequence repeat polymorphisms for the... Read More about Analysis of GABAA receptor subunit genes in multiplex pedigrees with manic depression.

Fertility and the menopause. (1994)
Journal Article
Chalmers, C. (1993). Fertility and the menopause. British Journal of Nursing, ISSN 0966-0461

An investigation into ways of encouraging the development of higher level cognitive skills in undergraduate biology students with reference to the Perry Scheme of Intellectual Development (1994)
Thesis
Harvey, J. M. An investigation into ways of encouraging the development of higher level cognitive skills in undergraduate biology students with reference to the Perry Scheme of Intellectual Development. (Thesis). Edinburgh Napier University. Retrieved fro

This project initially focused on a group poster presentation exercise which had the development of higher cognitive skills as its aims. A holistic approach was undertaken to the exercise which involved considering the relationship between all aspect... Read More about An investigation into ways of encouraging the development of higher level cognitive skills in undergraduate biology students with reference to the Perry Scheme of Intellectual Development.

Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons (1994)
Journal Article
Barnes Jr., E. M., Baumgartner, B. J., Harvey, R. J., & Darlison, M. G. (1994). Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons. Molecular Brain Research, 26(1-2), 9-17. https://d

Research report We have used quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to analyze the expression of {GABAA} receptor subunit genes in cultured neurons from the chick embryo cerebral cortex. During maturation of the neuro... Read More about Developmental up-regulation and agonist-dependent down-regulation of GABAA receptor subunit mRNAs in chick cortical neurons.

Toxoplasma Gondii: An Investigation of Infection in the Immunocompromised Host (1994)
Thesis
Nicoll, S. J. Toxoplasma Gondii: An Investigation of Infection in the Immunocompromised Host. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1052952

The aim of this study was to develop a sensitive and specific method of detecting Toxoplasma gondii in the immunocompromised host which would reduce the need for other tests and would ensure the prompt initiation of the appropriate treatment, the eff... Read More about Toxoplasma Gondii: An Investigation of Infection in the Immunocompromised Host.

Expression of transforming growth factor beta mRNA isoforms in human breast cancer (1994)
Journal Article
MacCallum, J., Bartlett, J., Thompson, A., Keen, J., Dixon, J., & Miller, W. (1994). Expression of transforming growth factor beta mRNA isoforms in human breast cancer. British Journal of Cancer, 69(6), 1006-1009. https://doi.org/10.1038/bjc.1994.197

Using an RNAse protection assay, expression of messenger RNA for isoforms of TGF-beta was determined in a series of breast cancers. Of 50 tumours, 45 (90%) expressed TGF-beta 1 mRNA, 39 (78%) expressed TGF-beta 2, and 47 (94%) expressed TGF-beta 3. P... Read More about Expression of transforming growth factor beta mRNA isoforms in human breast cancer.

Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain (1994)
Journal Article
Harvey, R. J., Schmitt, B., Hermans-Borgmeyer, I., Gundelfinger, E. D., Betz, H., & Darlison, M. G. (1994). Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain. Journal of Neurochemistry, 62(6)

Abstract: We report the isolation of a full-length clone from a Drosophila melanogaster head cDNA library that encodes a 614-residue polypeptide that exhibits all of the features of a ligand-gated chloride-channel/receptor subunit. This polypeptide,... Read More about Sequence of a Drosophila Ligand-Gated Ion-Channel Polypeptide with an Unusual Amino-Terminal Extracellular Domain.

The effects of work on food intake and ingestive behaviour of draught cattle and buffalo given barley straw (1994)
Journal Article
Pearson, R. A., & Smith, D. (1994). The effects of work on food intake and ingestive behaviour of draught cattle and buffalo given barley straw. Animal production, 58(03), 339-346. https://doi.org/10.1017/S0003356100007273

In the first experiment draught cattle and buffalo were worked for 5 h/day and/or given 17 h access to feed. In the second experiment they were worked for 4 h/day and/or given 20 h access to feed. When animals were prevented from feeding on barley st... Read More about The effects of work on food intake and ingestive behaviour of draught cattle and buffalo given barley straw.

Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis (1994)
Journal Article
Hicks, A. A., Bailey, M. E., Riley, B. P., Kamphuis, W., Siciliano, M. J., Johnson, K. J., & Darlison, M. G. (1994). Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis. Genomics, 20(2), 285-288. https://doi.org/10.1006/geno.1994.1167

GABAA receptors are hetero-oligomeric ion-channel complexes that are composed of combinations of α, β, γ, and δ subunits and play a major role in inhibitory neurotransmission in the mammalian brain. We report here a microsatellite polymorphism within... Read More about Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis.

Microbial metabolism of xenobiotics: Fundamental and applied research (1994)
Journal Article
Singleton, I. (1994). Microbial metabolism of xenobiotics: Fundamental and applied research. Journal of Chemical Technology and Biotechnology, 59(1), 9-23. doi:10.1002/jctb.280590104

The ability of microorganisms to metabolise xenobiotic compounds has received much attention due to the environmental persistence and toxicity of these chemicals. The microbial degradation of xenobiotics is seen as a cost effective method of removing... Read More about Microbial metabolism of xenobiotics: Fundamental and applied research.

Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit (1994)
Journal Article
Harvey, R. J., Chinchetru, M. A., & Darlison, M. G. (1994). Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit. Journal of

Complementary DNAs that encode two forms of the chicken -γ-aminobutyric acid type A (GABAA) receptor β2 subunit have been isolated. These polypeptides differ by the presence (β2L) or absence (β2S) of 17 amino acids, which contain a possible target fo... Read More about Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit.