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Outputs (11)

Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland (2023)
Journal Article
Garden, C. L. P. (2023). Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland. British Journal of Biomedical Science, 80, Article 11654. https://

Biomedical sciences graduates are employed in a variety of different settings and form a significant part of the Life Sciences sector workforce in Scotland. Their degrees should equip them with the skills and knowledge to not only enter the workplace... Read More about Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland.

Lego Serious Play: Building Engagement with Cell Biology (2022)
Journal Article
Garden, C. (2022). Lego Serious Play: Building Engagement with Cell Biology. Biochemistry and Molecular Biology Education, 50(2), 216-228. https://doi.org/10.1002/bmb.21608

A Lego Serious Play (LSP) - based exercise was developed to support student engagement with learning consolidation at the end of a first-year undergraduate cell biology course. The exercise was offered in addition to a regular revision session in pre... Read More about Lego Serious Play: Building Engagement with Cell Biology.

Immediate effect of a spinal mobilisation intervention on muscle stiffness, tone and elasticity in subjects with lower back pain – A randomised cross-over trial (2021)
Journal Article
Hamilton, R., Garden, C. L., & Brown, S. J. (2022). Immediate effect of a spinal mobilisation intervention on muscle stiffness, tone and elasticity in subjects with lower back pain – A randomised cross-over trial. Journal of Bodywork and Movement Therap

Background: Despite the lack of objective evidence, spinal manual therapies have been common practice for many years, particularly for treatment of lower back pain (LBP). This exploratory study measured and analysed the effect of a spinal mobilisatio... Read More about Immediate effect of a spinal mobilisation intervention on muscle stiffness, tone and elasticity in subjects with lower back pain – A randomised cross-over trial.

Gamification for student engagement: a framework (2021)
Journal Article
Rivera, E. S., & Garden, C. L. P. (2021). Gamification for student engagement: a framework. Journal of Further and Higher Education, 45(7), 999-1012. https://doi.org/10.1080/0309877x.2021.1875201

Gamification, the application of game elements to non-game situations, has gained traction in education as a mechanism for improving motivation and/or learning outcomes. Although it is widely accepted that gamification enhances these aspects of engag... Read More about Gamification for student engagement: a framework.

Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. (2013)
Journal Article
Szemes, M., Davies, R. L., Garden, C. L. P., & Usowicz, M. M. (2013). Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. Molecular Brain, 6, 33

BACKGROUND Down's syndrome (DS) is caused by triplication of all or part of human chromosome 21 and is characterized by a decrease in the overall size of the brain. One of the brain regions most affected is the cerebellum, in which the number of g... Read More about Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome..

Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome (2012)
Journal Article
Usowicz, M. M., & Garden, C. L. P. (2012). Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome. Brain Research, 1465, 10-17. https://doi.org/10.1016/j.brainres.2012.05.027

Down syndrome (DS) is characterized by intellectual disability and impaired motor control. Lack of coordinated movement, poor balance, and unclear speech imply dysfunction of the cerebellum, which is known to be reduced in volume in DS. The principal... Read More about Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome.

Hippocalcin functions as a calcium sensor in hippocampal LTD (2005)
Journal Article
Palmer, C., Lim, W., Hastie, P. G. R., Toward, M., Korolchuk, V. I., Burbidge, S. A., …Henley, J. M. (2005). Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron, 47(4), 487-494. https://doi.org/10.1016/j.neuron.2005.06.014

It is not fully understood how NMDAR-dependent LTD causes Ca2+-dependent endocytosis of AMPARs. Here we show that the neuronal Ca2+ sensor hippocalcin binds the β2-adaptin subunit of the AP2 adaptor complex and that along with GluR2 these coimmunopre... Read More about Hippocalcin functions as a calcium sensor in hippocampal LTD.

The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. (2005)
Journal Article
Palmer, C., Cotton, L., & Henley, J. M. (2005). The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacological Reviews, 57, 253-277. https://doi.org/10.1124/pr.57.2.7

-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs) are of fundamental importance in the brain. They are responsible for the majority of fast excitatory synaptic transmission, and their overactivation is potently excitotoxic. Recent fi... Read More about The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors..

Neuronal expression of the rat M1 muscarinic acetylcholine receptor gene is regulated by elements in the first exon (1999)
Journal Article
Wood, I. C., Garriga Canut, M., Palmer, C. L., Pepitoni, S., & Buckley, N. J. (1999). Neuronal expression of the rat M1 muscarinic acetylcholine receptor gene is regulated by elements in the first exon. Biochemical Journal, 340(2), 475-483. https://doi.or

Muscarinic acetylcholine receptor genes are members of the G-protein coupled receptor superfamily. Each member of this family studied to date appears to have a distinct expression profile, however the mechanisms determining these expression patterns... Read More about Neuronal expression of the rat M1 muscarinic acetylcholine receptor gene is regulated by elements in the first exon.