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Streptococci and Related Organism. (1992)
Book Chapter
Colman, G., Efstratiou, A., & Morrison, D. (1992). Streptococci and Related Organism. In R. G. Board, D. Jones, & F. A. Skinner (Eds.), Identification Methods in Applied and Environmental MicrobiologyWiley-Blackwell

Unusual effects of benzodiazepines and cyclodiene insecticides on an expressed invertebrate GABAAreceptor (1992)
Journal Article
Zaman, S. H., Harvey, R. J., Barnard, E. A., & Darlison, M. G. (1992). Unusual effects of benzodiazepines and cyclodiene insecticides on an expressed invertebrate GABAAreceptor. FEBS Letters, 307(3), 351-354. https://doi.org/10.1016/0014-5793%2892%2980711-o

We have previously reported [(1991) EMBO J. 10, 3239–3245] the sequence of an invertebrate γ‐aminobutyric acid (GABA) type A (GABAA) receptor polypeptide which forms homo‐oligomeric GABA‐gated, bicuculline‐sensitive, chloride‐ion channels upon hetero... Read More about Unusual effects of benzodiazepines and cyclodiene insecticides on an expressed invertebrate GABAAreceptor.

Assembly of functional GABAA receptors in insect cells using baculovirus expression vectors (1992)
Journal Article
Atkinson, A. E., Bermudez, I., Darlison, M. G., Barnard, E. A., Earley, F. G. P., Possee, R. D., Beadle, D. J., & King, L. A. (1992). Assembly of functional GABAA receptors in insect cells using baculovirus expression vectors. NeuroReport, 3(7), 597-600. https://doi.org/10.1097/00001756-199207000-00013

We have constructed recombinant baculoviruses containing cDNAs encoding either the [alpha]1- or the [beta]1-subunit of the bovine GABAA receptor. In Spodoptera frugiperda (IPLB-Sf-21) cells infected with recombinant virus expressing either the [alpha... Read More about Assembly of functional GABAA receptors in insect cells using baculovirus expression vectors.

Fine mapping of the human biglycan (BGN) gene within the Xq28 region employing a hybrid cell panel (1992)
Journal Article
Traupe, H., Ouweland, A. M. V. D., Oost, B. A. V., Vogel, W., Vetter, U., Warren, S. T., Rocchi, M., Darlison, M. G., & Ropers, H. (1992). Fine mapping of the human biglycan (BGN) gene within the Xq28 region employing a hybrid cell panel. Genomics, 13(2), 481-483. https://doi.org/10.1016/0888-7543%2892%2990279-2

Human biglycan is a small proteoglycan that is expressed at high levels in the growing skeleton and in human skin at the cell surface of differentiating keratinocytes. The human gene for biglycan (BGN) has previously been mapped by in situ hybridizat... Read More about Fine mapping of the human biglycan (BGN) gene within the Xq28 region employing a hybrid cell panel.

Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid (1992)
Journal Article
Zaman, S. H., Shingai, R., Harvey, R. J., Darlison, M. G., & Barnard, E. A. (1992). Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid. European journal of pharmacology. Molecular pharmacology section, 225(4), 321-330. https://doi.org/10.1016/0922-4106%2892%2990106-6

When vertebrate brain poly(A)+ RNA is expressed in Xenopus oocytes the response of the GABA receptors formed is found to be inhibited allosterically by a neurosteroid, pregnenolone sulphate (PS). This negative modulation was reproduced after expressi... Read More about Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid.

Differential Localization of Two Alternatively Spliced GABAAReceptor γ2-Subunit mRNAs in the Chick Brain (1992)
Journal Article
Glencorse, T. A., Bateson, A. N., & Darlison, M. G. (1992). Differential Localization of Two Alternatively Spliced GABAAReceptor γ2-Subunit mRNAs in the Chick Brain. European Journal of Neuroscience, 4(3), 271-277. https://doi.org/10.1111/j.1460-9568.1992.tb00874.x

Two variants of the GABAA receptor γ2 subunit are known to exist, which differ by the presence (γ2L) or absence (γ2S) of eight amino acids in the presumed intracellular loop between the third and fourth membrane-spanning domains. These variants have... Read More about Differential Localization of Two Alternatively Spliced GABAAReceptor γ2-Subunit mRNAs in the Chick Brain.

Computer-enhanced learning in tertiary education (1991)
Thesis
Mackie, D. M. Computer-enhanced learning in tertiary education. (Thesis). Edinburgh Polytechnic. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/7310

It is widely accepted that mathematics courses for science and engineering undergraduates should aim to develop an enquiring and creative approach to mathematics together with good communication skills. Due to their versatility, computational power a... Read More about Computer-enhanced learning in tertiary education.

Distribution of the GABAA receptor α1- and γ2-subunit mRNAs in chick brain (1991)
Journal Article
Glencorse, T. A., Bateson, A. N., Hunt, S. P., & Darlison, M. G. (1991). Distribution of the GABAA receptor α1- and γ2-subunit mRNAs in chick brain. Neuroscience Letters, 133(1), 45-48. https://doi.org/10.1016/0304-3940%2891%2990053-v

We have used sequence-specific oligonucleotide probes and in situ hybridisation histochemistry to examine the distributions of the GABAA receptor α1- and γ2-subunit mRNAs in serial sections of 1-day-old chick brain. Both transcripts are present toget... Read More about Distribution of the GABAA receptor α1- and γ2-subunit mRNAs in chick brain.

Cloning of a cDNA that encodes an invertebrate glutamate receptor subunit (1991)
Journal Article
Hutton, M. L., Harvey, R. J., Barnard, E. A., & Darlison, M. (1991). Cloning of a cDNA that encodes an invertebrate glutamate receptor subunit. FEBS Letters, 292(1-2), 111-114. https://doi.org/10.1016/0014-5793%2891%2980846-u

A full‐length cDNA which encodes a putative glutamate receptor polypeptide was isolated from the pond snailLymnaea stagnalis, using a short stretch of exonic sequence and two variants of the polymerase chain reaction. In this first comparison of inve... Read More about Cloning of a cDNA that encodes an invertebrate glutamate receptor subunit.

A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia. (1991)
Thesis
Crerar, M. A. A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia. (Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/4968

This thesis investigates impairments of written sentence comprehension in 14
aphasic adults. The primary purpose of the research was to apply computer
technology to the process of assessment, with the aim of improving diagnostic
precision and ther... Read More about A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia..

Conserved Organization of ?-Aminobutyric AcidAReceptor Genes: Cloning and Analysis of the Chicken ?4-Subunit Gene (1991)
Journal Article
Lasham, A., Vreugdenhil, E., Bateson, A. N., Barnard, E. A., & Darlison, M. G. (1991). Conserved Organization of ?-Aminobutyric AcidAReceptor Genes: Cloning and Analysis of the Chicken ?4-Subunit Gene. Journal of Neurochemistry, 57(1), 352-355. https://doi.org/10.1111/j.1471-4159.1991.tb02135.x

Abstract: A series of genomic clones containing DNA that encodes the chicken γ-aminobutyric acidA (GABAA) receptor β4 subunit have been isolated. These have been restriction mapped and partially sequcnced to determine the structural organization and... Read More about Conserved Organization of ?-Aminobutyric AcidAReceptor Genes: Cloning and Analysis of the Chicken ?4-Subunit Gene.

The effect of acidification on epilithic algae in the Loch Ard catchment. (1991)
Thesis
Kinross, J. H. The effect of acidification on epilithic algae in the Loch Ard catchment. (Thesis). Napier Polytechnic of Edinburgh. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/2811

A survey of epilithic filamentous algae was carried out at 15 sites on 10 streams with a range of mean pH from 4.37 to 6.67 in the Loch Ard area of the Trossachs, between 1986 and 1988. Monitoring of physical and chemical parameters was carried out i... Read More about The effect of acidification on epilithic algae in the Loch Ard catchment..

Rondo Forest Reserve, Tanzania: an ornithological note including new records of the East Coast Akalat Sheppardia gunningi, the Spotted Ground Thrush Turdus fischeri, and the Rondo Green Barbet Stactolaema olivacea woodwardi (1991)
Journal Article
Holsten, B., Bräunlich, A., & Huxham, M. (1991). Rondo Forest Reserve, Tanzania: an ornithological note including new records of the East Coast Akalat Sheppardia gunningi, the Spotted Ground Thrush Turdus fischeri, and the Rondo Green Barbet Stactolaema olivacea woodwardi. Scopus, 14(2), (125-128). ISSN 0250-4162

The Rondo Forest Reserve is a semi-deciduous coastal forest situated at 10°10S, 39°15E in southern Tanzania, 77 km by road from the coastal town of Lindi. The forest isheterogeneous, with substantial numbers of large canopy trees, such as Chlorophora... Read More about Rondo Forest Reserve, Tanzania: an ornithological note including new records of the East Coast Akalat Sheppardia gunningi, the Spotted Ground Thrush Turdus fischeri, and the Rondo Green Barbet Stactolaema olivacea woodwardi.

Preliminary assessment of forest birds in Kiono, Pande, Kisiju and Kiwengoma coastal forests, Tanzania (1991)
Journal Article
Burgess, N. D., Huxham, M. R., Mlingwa, C. O. F., Davies, S. G. F., & Cutts, C. J. (1991). Preliminary assessment of forest birds in Kiono, Pande, Kisiju and Kiwengoma coastal forests, Tanzania. Scopus, 14(2), ISSN 0250-4162

A preliminary assessment of the forest birds in four Tanzanian coastal forests (Kiono, Pande, Kisiju and Kiwengoma) is presented. Up to 51 species of forest bird were recorded from a single forest, with diversity declining in a sequence: Kiono; Kiwen... Read More about Preliminary assessment of forest birds in Kiono, Pande, Kisiju and Kiwengoma coastal forests, Tanzania.

Genetic mapping of the mouse X chromosome in the region homologous to human Xq27–Xq28 (1991)
Journal Article
Herman, G. E., Faust, C. J., Darlison, M. G., & Barnard, E. A. (1991). Genetic mapping of the mouse X chromosome in the region homologous to human Xq27–Xq28. Genomics, 9(4), 670-677. https://doi.org/10.1016/0888-7543%2891%2990360-q

The four loci Gabra3, DXPas8, CamL1, and Bpa, located near the murine X-linked visual pigment gene (Rsup), have been ordered using 248 backcross progeny from an interspecific mating of (B6CBA-Aw-JA-Bpa) and Mus spretus. One hundred twenty backcross p... Read More about Genetic mapping of the mouse X chromosome in the region homologous to human Xq27–Xq28.

y-Aminobutyric AcidA Receptor Heterogeneity Is Increased by Alternative Splicing of a Novel ?-Subunit Gene Transcript (1991)
Journal Article
Bateson, A. N., Lasham, A., & Darlison, M. G. (1991). y-Aminobutyric AcidA Receptor Heterogeneity Is Increased by Alternative Splicing of a Novel ?-Subunit Gene Transcript. Journal of Neurochemistry, 56(4), 1437-1440. https://doi.org/10.1111/j.1471-4159.1991.tb11443.x

Abstract: DNA sequences encoding two variants of a novel γ-aminobutyric acidA (GABAA) receptor β subunit were isolated from an embryonic chicken whole-brain cDNA library and a chicken genomic library. The coding regions of these variants only differ... Read More about y-Aminobutyric AcidA Receptor Heterogeneity Is Increased by Alternative Splicing of a Novel ?-Subunit Gene Transcript.

The chicken GABAA receptor α1 subunit: cDNA sequence and localization of the corresponding mRNA (1991)
Journal Article
Bateson, A. N., Harvey, R. J., Wisden, W., Glencorse, T. A., Hicks, A. A., Hunt, S. P., Barnard, E. A., & Darlison, M. G. (1991). The chicken GABAA receptor α1 subunit: cDNA sequence and localization of the corresponding mRNA. Molecular Brain Research, 9(4), 333-339. https://doi.org/10.1016/0169-328x%2891%2990081-8

We report the sequence of a complementary {DNA} (cDNA) that encodes the chicken {GABAA} receptor α1 subunit, which is extremely homologous to mammalian α1 subunits. The distribution of α1 subunit transcripts is shown to correlate mainly, but not comp... Read More about The chicken GABAA receptor α1 subunit: cDNA sequence and localization of the corresponding mRNA.