Skip to main content

Research Repository

Advanced Search

All Outputs (161)

Using network analysis metrics to discover functionally important methods in large-scale software systems (2012)
Presentation / Conference Contribution
Pakhira, A., & Andras, P. (2012). Using network analysis metrics to discover functionally important methods in large-scale software systems. In 2012 3rd International Workshop on Emerging Trends in Software Metrics (WETSoM) (70-76)

In large-scale software systems that integrate many components originating from different vendors, the understanding of the functional importance of the components is critical for the dependability of the system. However, in general, gaining such und... Read More about Using network analysis metrics to discover functionally important methods in large-scale software systems.

Assessing motor performance with PCA (2011)
Presentation / Conference Contribution
Hammerla, N. Y., Plötz, T., Andras, P., & Olivier, P. (2011). Assessing motor performance with PCA. In Proceedings of the International Workshop on Frontiers in Activity Recognition using Pervasive Sensing (18-23)

Information about the motor performance, i.e. how well an activity is performed, is valuable information for a variety of novel applications in Activity Recognition (AR). Its assessment represents a significant challenge, as requirements depend on th... Read More about Assessing motor performance with PCA.

Towards neuro-silicon interface using reconfigurable dynamic clamping (2011)
Presentation / Conference Contribution
Luo, J. W., Mak, T., Yu, B., Andras, P., & Yakovlev, A. (2011, August). Towards neuro-silicon interface using reconfigurable dynamic clamping. Presented at 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Boston, MA, USA

Dynamic clamp emerges as an important apparatus to study the intrinsic neuronal properties through close-loop interactions between models and biological neurons. Modelling large-scale neuronal networks in software will result in significant computati... Read More about Towards neuro-silicon interface using reconfigurable dynamic clamping.

Simultaneous measurement of membrane potential changes in multiple pattern generating neurons using voltage sensitive dye imaging (2011)
Journal Article
Städele, C., Andras, P., & Stein, W. (2012). Simultaneous measurement of membrane potential changes in multiple pattern generating neurons using voltage sensitive dye imaging. Journal of Neuroscience Methods, 203(1), 78-88. https://doi.org/10.1016/j.jneumeth.2011.09.015

Optical imaging using voltage-sensitive dyes (VSDs) is a promising technique for the simultaneous activity recording of many individual neurons. While such simultaneous recordings are critical for the understanding of the integral functionality of ne... Read More about Simultaneous measurement of membrane potential changes in multiple pattern generating neurons using voltage sensitive dye imaging.

Research: metrics, quality, and management implications (2011)
Journal Article
Andras, P. (2011). Research: metrics, quality, and management implications. Research Evaluation, 20(2), 90-106. https://doi.org/10.3152/095820211X12941371876265

Research evaluation is increasingly important in management decisions in universities. Research metrics provide an objective way to assess the research output of individuals, groups, departments and universities. Such metrics work well as quality ass... Read More about Research: metrics, quality, and management implications.

Validation of Network Analysis Methods Applied in the Context of Dynamic Analysis of Software Systems (2011)
Report
Pakhira, A., & Andras, P. (2011). Validation of Network Analysis Methods Applied in the Context of Dynamic Analysis of Software Systems. Newcastle upon Tyne: Newcastle University

Evolution of large-scale software systems generates very complex systems. The combination of network analysis with dynamic analysis provides a promising approach to understand such systems and support their maintenance and evolution. However, an impo... Read More about Validation of Network Analysis Methods Applied in the Context of Dynamic Analysis of Software Systems.

Dynamic network analysis of software systems (2011)
Report
Pakhira, A., & Andras, P. (2011). Dynamic network analysis of software systems. Newcastle: University of Newcastle upon Tyne

It is difficult to analyse large-scale integrated software systems with the purpose of improving their dependability and functionality through maintenance and evolution. Such systems contain many interactions between their components and can be repre... Read More about Dynamic network analysis of software systems.

Optical imaging of neurons in the crab stomatogastric ganglion with voltage-sensitive dyes (2011)
Journal Article
Stein, W., Staedele, C., & Andras, P. (2011). Optical imaging of neurons in the crab stomatogastric ganglion with voltage-sensitive dyes. Journal of Visualized Experiments, 49, Article e2567. https://doi.org/10.3791/2567

Voltage-sensitive dye imaging of neurons is a key methodology for the understanding of how neuronal networks are organised and how the simultaneous activity of participating neurons leads to the emergence of the integral functionality of the network.... Read More about Optical imaging of neurons in the crab stomatogastric ganglion with voltage-sensitive dyes.

A critical analysis of the combined usage of protein localization prediction methods: Increasing the number of independent data sets can reduce the accuracy of predicted mitochondrial localization (2010)
Journal Article
Lythgow, K. T., Hudson, G., Andras, P., & Chinnery, P. F. (2011). A critical analysis of the combined usage of protein localization prediction methods: Increasing the number of independent data sets can reduce the accuracy of predicted mitochondrial localization. Mitochondrion, 11(3), 444-449. https://doi.org/10.1016/j.mito.2010.12.016

In the absence of a comprehensive experimentally derived mitochondrial proteome, several bioinformatic approaches have been developed to aid the identification of novel mitochondrial disease genes within mapped nuclear genetic loci. Often, many class... Read More about A critical analysis of the combined usage of protein localization prediction methods: Increasing the number of independent data sets can reduce the accuracy of predicted mitochondrial localization.

Single-sweep voltage-sensitive dye imaging of interacting identified neurons (2010)
Journal Article
Stein, W., Städele, C., & Andras, P. (2011). Single-sweep voltage-sensitive dye imaging of interacting identified neurons. Journal of Neuroscience Methods, 194(2), 224-234. https://doi.org/10.1016/j.jneumeth.2010.10.007

The simultaneous recording of many individual neurons is fundamental to understanding the integral functionality of neural systems. Imaging with voltage-sensitive dyes (VSDs) is a key approach to achieve this goal and a promising technique to supplem... Read More about Single-sweep voltage-sensitive dye imaging of interacting identified neurons.

A model of endocannabinoid 2-AG-mediated depolarization-induced suppression of inhibition (2010)
Presentation / Conference Contribution
Fox, D., & Andras, P. (2010). A model of endocannabinoid 2-AG-mediated depolarization-induced suppression of inhibition. BMC Neuroscience, 11, Article P189 (2010). https://doi.org/10.1186/1471-2202-11-S1-P189

Depolarization-induced suppression of inhibition (DSI) is known to be mediated by the endocannabinoid 2-arachidonoylglycerol (2-AG). It's calcium-dependent production and subsequent retrograde diffusion from postsynaptic pyramidal cells to presynapti... Read More about A model of endocannabinoid 2-AG-mediated depolarization-induced suppression of inhibition.

Light-induced effects of a fluorescent voltage-sensitive dye on neuronal activity in the crab stomatogastric ganglion (2010)
Journal Article
Stein, W., & Andras, P. (2010). Light-induced effects of a fluorescent voltage-sensitive dye on neuronal activity in the crab stomatogastric ganglion. Journal of Neuroscience Methods, 188(2), 290-294. https://doi.org/10.1016/j.jneumeth.2010.03.003

Optical imaging being one of the cutting-edge methods for the investigation of neural activity, it is very important to understand the mechanisms of how dye molecules work and the range of side effects that they may induce. In particular, it is very... Read More about Light-induced effects of a fluorescent voltage-sensitive dye on neuronal activity in the crab stomatogastric ganglion.

Networks of artificial social interactions (2009)
Presentation / Conference Contribution
Andras, P. (2009, September). Networks of artificial social interactions. Presented at ECAL: European Conference on Artificial Life, Budapest, Hungary

Evolution of cooperation is a fundamental question of socio-biology. Intrinsic factors like kinship play an important role in cooperation among selfish individuals. External factors like uncertainty and the structure of the social interaction network... Read More about Networks of artificial social interactions.

Modeling living systems (2009)
Presentation / Conference Contribution
Andras, P. (2009, September). Modeling living systems. Presented at ECAL: European Conference on Artificial Life, Budapest, Hungary

A fundamental issue of evolution of life is the emergence and maintenance of self-referential autocatalytic systems (e.g. living cells). In this paper the problem is analyzed from a computational perspective. It is proposed that such systems have to... Read More about Modeling living systems.

Molecular neuroimaging – A proposal for a novel approach to high resolution recording of neural activity in nervous systems (2009)
Journal Article
Andras, P. (2009). Molecular neuroimaging – A proposal for a novel approach to high resolution recording of neural activity in nervous systems. https://doi.org/10.1016/j.mehy.2009.06.056

Neuroimaging is a key methodology for the understanding of how neural systems work and how neurodynamics leads to neurally controlled behavior in animals. Current neuroimaging methods (e.g. fMRI, MEG, voltage-sensitive dye imaging) provide a critical... Read More about Molecular neuroimaging – A proposal for a novel approach to high resolution recording of neural activity in nervous systems.

Why are top universities losing their lead? An economics modelling-based approach (2009)
Journal Article
Andras, P., & Charlton, B. G. (2009). Why are top universities losing their lead? An economics modelling-based approach. Science and Public Policy, 36(4), 317-330. https://doi.org/10.3152/030234209X436563

Scientific output of lower-ranked institutions is catching up with leading universities. We present a simple, conceptual model of research production describing the dynamic interaction between inputs (research staff and funding) and outputs (publicat... Read More about Why are top universities losing their lead? An economics modelling-based approach.

The Sleep Elaboration–Awake Pruning (SEAP) theory of memory: Long term memories grow in complexity during sleep and undergo selection while awake. Clinical, psychopharmacological and creative implications (2009)
Journal Article
Charlton, B. G., & Andras, P. (2009). The Sleep Elaboration–Awake Pruning (SEAP) theory of memory: Long term memories grow in complexity during sleep and undergo selection while awake. Clinical, psychopharmacological and creative implications. Medical Hypotheses, 73(1), 1-4. https://doi.org/10.1016/j.mehy.2009.03.005

Identifying components of a network having high importance for network integrity (2009)
Patent
Young, M. P., Andras, P. E., & O'Neill, M. A. (2009). Identifying components of a network having high importance for network integrity. US20090062136A1

A computer system (2) is provided which is arranged to receive network data (1) identifying nodes and links between nodes. The computer system (2) processes the input network data (1) to utilise the network topology to identify nodes and links having... Read More about Identifying components of a network having high importance for network integrity.

Uncertainty and communication complexity in iterated cooperation games (2008)
Presentation / Conference Contribution
Andras, P. (2008). Uncertainty and communication complexity in iterated cooperation games. In Artificial Life XI 2008 (9-16)

Iterated cooperation games (e.g. Prisoner’s Dilemma) are used to analyze the emergence and evolution of cooperation among selfish individuals. Uncertainty of outcomes of games is an important factor that influences the level of cooperation. Communica... Read More about Uncertainty and communication complexity in iterated cooperation games.