Jun Wen Luo
Towards neuro-silicon interface using reconfigurable dynamic clamping
Luo, Jun Wen; Mak, Terrence; Yu, Bo; Andras, Peter; Yakovlev, Alex
Authors
Terrence Mak
Bo Yu
Prof Peter Andras P.Andras@napier.ac.uk
Dean of School of Computing Engineering and the Built Environment
Alex Yakovlev
Abstract
Dynamic clamp emerges as an important apparatus to study the intrinsic neuronal properties through close-loop interactions between models and biological neurons. Modelling large-scale neuronal networks in software will result in significant computational delay that becomes a bottleneck to apply dynamic clamp for more complicated systems. In this paper, we present a real-time dynamic clamping system based on field programmable gate arrays (FPGAs) to accelerate the necessary computations. It also provides a flexible platform to reconfigure various model parameters and topologies. Realtime neuronal and synaptic models were implemented in FPGA, and interconnected with the stomatograstric ganglion (STG) nervous system to exemplify the real-time dynamics. Results show that our method can be effectively configured to mimic various biological neural networks and is two orders of magnitude faster than software approach using desktop computer.
Presentation Conference Type | Conference Paper (Published) |
---|---|
Conference Name | 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
Start Date | Aug 30, 2011 |
End Date | Sep 3, 2011 |
Online Publication Date | Dec 1, 2011 |
Publication Date | 2011 |
Deposit Date | Nov 17, 2021 |
Publisher | Institute of Electrical and Electronics Engineers |
Pages | 6389-6392 |
Series ISSN | 1558-4615 |
Book Title | 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society |
DOI | https://doi.org/10.1109/IEMBS.2011.6091577 |
Keywords | Field programmable gate arrays, Biological system modeling, Computational modeling, Neurons, Clamps, Electric potential |
Public URL | http://researchrepository.napier.ac.uk/Output/2809307 |
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