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All Outputs (75)

Assessing the link between stress and retention and the existence of barriers to support service use within HE (2015)
Journal Article
Campbell Casey, S., Westbury, T., Florida-James, G., Harris, P., Campbell, S. A., Westbury, T., & Florida-James, G. (2016). Assessing the link between stress and retention and the existence of barriers to support service use within HE. Journal of Further

Students suffer from stress as a result of many factors, including educational unpreparedness, financial strain and inability to integrate socially. This mixed methods study aimed to investigate stress levels of undergraduate students in a post-1992,... Read More about Assessing the link between stress and retention and the existence of barriers to support service use within HE.

Sleep disruption and its effect on lymphocyte redeployment following an acute bout of exercise (2015)
Journal Article
Florida-James, G. D., Ingram, L. A., Simpson, R. J., Malone, E., & Florida-James, G. (2015). Sleep disruption and its effect on lymphocyte redeployment following an acute bout of exercise. Brain, Behavior, and Immunity, 47, 100-108. https://doi.org/10.101

Sleep disruption and deprivation are common in contemporary society and have been linked with poor health, decreased job performance and increased life-stress. The rapid redeployment of lymphocytes between the blood and tissues is an archetypal featu... Read More about Sleep disruption and its effect on lymphocyte redeployment following an acute bout of exercise.

Lung Inflammation, oxidative stress and air pollution. (2014)
Book Chapter
Gomes, E. C., & Florida-James, G. (2014). Lung Inflammation, oxidative stress and air pollution. In K. C. Ong (Ed.), Lung InflammationInTech. https://doi.org/10.5772/58252

This is a very relevant chapter in the context of “Lung Inflammation” because it details and discusses an important theme in this area: air pollution. The analyses of epidemiological studies, conducted in various urban centres, have provided coherent... Read More about Lung Inflammation, oxidative stress and air pollution..

Injury occurrence and mood states during a desert ultramarathon (2012)
Journal Article
Graham, S. M., McKinley, M., Chris, C. C., Westbury, T., Baker, J. S., Kilgore, L., & Florida-James, G. (2012). Injury occurrence and mood states during a desert ultramarathon. Clinical Journal of Sport Medicine, 22(6), 462-466. https://doi.org/10.1097/js

Objective: To describe injuries and illnesses presented and profile mood states and sleep patterns during a desert environment ultramarathon. Design: Prospective study gathering data on mood states and injury patterns. Setting: Gobi Desert, Mongoli... Read More about Injury occurrence and mood states during a desert ultramarathon.

Effect of vitamin supplementation on lung injury and running performance in a hot, humid, and ozone-polluted environment: Antioxidants on lung injury and performance (2011)
Journal Article
Gomes, E. C., Allgrove, J. E., Florida-James, G., & Stone, V. (2011). Effect of vitamin supplementation on lung injury and running performance in a hot, humid, and ozone-polluted environment: Antioxidants on lung injury and performance. Scandinavian Journ

In this study, the effect of vitamin C and E supplementation on lung injury and performance of runners were analyzed. Using a randomized, double-blinded, crossover design, nine runners participated in two experimental trials: a 2-week Vitamin trial (... Read More about Effect of vitamin supplementation on lung injury and running performance in a hot, humid, and ozone-polluted environment: Antioxidants on lung injury and performance.

Impact of heat and pollution on oxidative stress and CC16 secretion after 8 km run (2011)
Journal Article
Gomes, E. C., Stone, V., & Florida-James, G. (2011). Impact of heat and pollution on oxidative stress and CC16 secretion after 8 km run. European Journal of Applied Physiology, 111(9), 2089-2097. https://doi.org/10.1007/s00421-011-1839-x

To investigate the acute effect of a hot, humid and ozone-polluted (O3) environment on lung inflammation and oxidative tress of runners performing 8 km time trial run. Using a single-blinded randomized design, 10 male athletes (mean V˙O2max = 64.4 ml... Read More about Impact of heat and pollution on oxidative stress and CC16 secretion after 8 km run.

Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task (2010)
Journal Article
Simpson, R. J., Graham, S. M., Florida-James, G. D., Connaboy, C., Clement, R., & Jackson, A. S. (2010). Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task. Applied

Identifying field measures to estimate backpack load-carriage work intensity in elite soldiers is of interest to the military. This study developed rating of perceived exertion (RPE) and heart rate models to define metabolic workload for a backpack l... Read More about Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task.

The impact of acute strenuous exercise on TLR2, TLR4 and HLA.DR expression on human blood monocytes induced by autologous serum (2010)
Journal Article
Florida-James, G. D., McFarlin, B. K., O’Connor, D. P., Simpson, R. J., Booth, S., Florida-James, G., …Simpson, R. J. (2010). The impact of acute strenuous exercise on TLR2, TLR4 and HLA.DR expression on human blood monocytes induced by autologous ser

Acute exercise alters the surface expression of toll-like receptors (TLRs) and HLA.DR on blood monocytes, which could transiently compromise immunity. As serum factors might be responsible, we examined the effects of autologous post-exercise serum ex... Read More about The impact of acute strenuous exercise on TLR2, TLR4 and HLA.DR expression on human blood monocytes induced by autologous serum.

Investigating performance and lung function in a hot, humid and ozone-polluted environment (2010)
Journal Article
Gomes, E. C., Stone, V., & Florida-James, G. (2010). Investigating performance and lung function in a hot, humid and ozone-polluted environment. European Journal of Applied Physiology, 110(1), 199-205. https://doi.org/10.1007/s00421-010-1485-8

Large urbanized areas, where sports events take place, have a polluted environment and can also reach high temperatures and humidity levels. The aim of this study was to investigate the impact of a hot, humid and ozone-polluted (O3) environment on (1... Read More about Investigating performance and lung function in a hot, humid and ozone-polluted environment.

Reliability Study Of The Technique To Assess Upper Respiratory Airway Inflammation In A Polluted Environment: 1695 (2009)
Journal Article
Gomes, E. C., Florida-James, G., & Stone, V. (2009). Reliability Study Of The Technique To Assess Upper Respiratory Airway Inflammation In A Polluted Environment: 1695. Medicine and Science in Sports and Exercise, 41(Supplement 1), 99. https://doi.org/10.

Airway inflammation can be detected by an increased influx of inflammatory cells, such as neutrophils, as well as increased expression of inflammatory markers, which include interleukin-6 (IL-6) and Clara cell protein (CC16). When an individual is ex... Read More about Reliability Study Of The Technique To Assess Upper Respiratory Airway Inflammation In A Polluted Environment: 1695.

Metabolic Differences Between Backpack Walking And Running At A Fixed Treadmill Velocity In 'Elite" British Soldiers: A Pilot Study: 708 (2009)
Journal Article
Graham, S. M., Florida-James, G. D., Connaboy, C., Clement, R., & Simpson, R. J. (2009). Metabolic Differences Between Backpack Walking And Running At A Fixed Treadmill Velocity In 'Elite" British Soldiers: A Pilot Study: 708. Medicine and Science in Spor

Soldiers who serve in the "elite" units of the British Army are expected to "speed march" carrying heavy backpack loads, which involves a combination of both running and fast walking movements as an individual and in groups. It is generally accepted... Read More about Metabolic Differences Between Backpack Walking And Running At A Fixed Treadmill Velocity In 'Elite" British Soldiers: A Pilot Study: 708.

Resting Blood Lymphocytes Are Activated By Autologous Serum After A 40km Cycling Time Trial: 542 (2009)
Journal Article
Simpson, R. J., Bartlett, D. B., Booth, S., Florida-James, G. D., & McFarlin, B. K. (2009). Resting Blood Lymphocytes Are Activated By Autologous Serum After A 40km Cycling Time Trial: 542. Medicine and Science in Sports and Exercise, 41(Supplement 1), 7.

PURPOSE: Although it is known that peripheral blood lymphocytes display an activated phenotype immediately after an acute bout of high-intensity exercise, it is not known if these lymphocytes are activated by exercise or whether this is due to a mobi... Read More about Resting Blood Lymphocytes Are Activated By Autologous Serum After A 40km Cycling Time Trial: 542.

Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise (2008)
Journal Article
Simpson, R. J., Cosgrove, C., Ingram, L. A., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2008). Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise. Brain, Behavior, and Immunity, 22(4), 544-551. https://doi.org/10.1016/j.bbi.2007.11.002

Senescent T-lymphocytes are antigen-experienced cells that express the killer-cell lectin-like receptor G1 (KLRG1) and/or CD57; fail to clonally expand following further antigenic stimulation and prevail in the resting blood of older adults compared... Read More about Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise.

Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise (2007)
Journal Article
Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G., & Simpson, R. J. (2008). Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain, Behavior, and Immunity, 22(3), 375-380. https://doi.org/10.1016/j.bbi.2007.09.001

Cytotoxic T-lymphocytes co-express the T-cell receptor, CD3 and the MHC I restricted antigen CD8. Although total CD8 expression is often used to identify CD8+ T-cells in blood, errors are associated with this method as some CD3 negative natural kille... Read More about Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise.

Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Black, J., Ross, J., & Guy, K. (2007). Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. Research in Sports Medicine, 15, 157-174. https://doi.org/10.1080/15438620701405339

The lymphocytopenia that occurs during the recovery stage of exercise may be a result of apoptosis through an increased expression of CD95, a loss of the complement regulatory proteins CD55 and CD59, or both. Trained subjects completed intensive, mod... Read More about Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans..

Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384 (2007)
Journal Article
Graham, S. M., Simpson, R. J., Clement, R., & Florida-James, G. D. (2007). Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384. Medicine and Science in Sports and Exercise, 39(Supplement), S199

PURPOSE: To identify indicators of backpack running performance in “elite” British soldiers using an extensive range of physiological and anthropometrical variables. METHODS: Thirteen male soldiers (mean ± SD: Age: 26 ± 4 yrs; VO2peak: 55.1 ± 5.4) f... Read More about Physiological and Anthropometrical Indicators of Backpack Running Performance in ??Elite?? British Soldiers: 1384.

High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781 (2007)
Journal Article
Simpson, R. J., Cosgrove, C., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2007). High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781. Medicine and Science in Sports

T-cell senescence occurs during aging as a consequence of chromosome telomere shortening in response to repetitive antigenic stimulation. Senescent T-lymphocytes normally exhibit a “memory” phenotype (i.e. CD62L-/CD45RA-/CD45RO+) and express CD57 and... Read More about High-Intensity Exercise Mobilises Senescent T-lymphocytes into the Peripheral Blood Compartment in Young and Old Subjects: 781.

High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H., & Guy, K. (2007). High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. Journal of Applied Physiology, 103, 396-401. https://doi.org/10.1152/japplphysiol.00007.2007

Clonal expansion of T lymphocytes in response to antigenic stimulation is a fundamental process of adaptive immunity. As a consequence of clonal expansion, some T lymphocytes acquire a senescent phenotype, fail to replicate in response to further ant... Read More about High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects..