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Outputs (14)

Applied anatomy and physiology and the renal disease process (2019)
Book Chapter
Chalmers, C. (2019). Applied anatomy and physiology and the renal disease process. In Renal nursing: Care and management of people with kidney disease (21-58). (5). Wiley. https://doi.org/10.1002/9781119413172.ch2

This chapter provides the reader with a detailed discussion of all aspects of renal physiology and its relationship to important pathophysiological processes in renal disease, and some brief discussion on related nursing observations. It first explor... Read More about Applied anatomy and physiology and the renal disease process.

The Ex Vivo Organ Culture of Bone (2019)
Book Chapter
Staines, K. A., Brown, G., & Farquharson, C. (2019). The Ex Vivo Organ Culture of Bone. In Bone Research Protocols (199-215). Humana Press. https://doi.org/10.1007/978-1-4939-8997-3_10

The ex vivo organ culture of bone provides many of the advantages of both the whole organism and isolated cell strategies and can deliver valuable insight into the network of processes and activities that are fundamental to bone and cartilage biology... Read More about The Ex Vivo Organ Culture of Bone.

Antiviral host defence peptides. (2016)
Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016). Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents (57-94). Springer. https://doi.org/10.1007/978-3-319-32949-9_3

The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The antiviral activity of cationic host defence peptides is of significant interest... Read More about Antiviral host defence peptides..

Regulation of capsule expression (2010)
Book Chapter
Taylor, C., & Roberts, I. S. (2010). Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences (115-138). Cambridge University Press

No abstract available.

GABA-, Glycine-, and Glutamate-Gated Channels and Their Possible Involvement in Neurological and Psychiatric Illness (1996)
Book Chapter
Darlison, M. G., & Harvey, R. J. (1996). GABA-, Glycine-, and Glutamate-Gated Channels and Their Possible Involvement in Neurological and Psychiatric Illness. In Molecular Biology of Membrane Transport Disorders (169-180). Springer. https://doi.org/10.1007/978-1-4613-1143-0_9

Rapid chemical communication between cells in the vertebrate central nervous system is mediated by ligand-gated ion-channel receptors (also called ionotropic receptors), which are multisubunit complexes, that each contain an ion-selective channel. In... Read More about GABA-, Glycine-, and Glutamate-Gated Channels and Their Possible Involvement in Neurological and Psychiatric Illness.

Molluscan ligand-gated ion-channel receptors (1993)
Book Chapter
Darlison, M. G., Hutton, M. L., & Harvey, R. J. (1993). Molluscan ligand-gated ion-channel receptors. In Comparative Molecular Neurobiology (48-64). Springer. https://doi.org/10.1007/978-3-0348-7265-2_3

In this chapter we introduce the reader to the structures of the different types of ligand-gated ion-channel receptor, and the numerous receptor subtypes that have recently been revealed to exist, in both invertebrate and vertebrate species, by the a... Read More about Molluscan ligand-gated ion-channel receptors.

The Isolation of Genomic DNA from Invertebrates (1992)
Book Chapter
Vreugdenhil, E., & Darlison, M. G. (1992). The Isolation of Genomic DNA from Invertebrates. In A. Longstaff, & P. Revest (Eds.), Protocols in Molecular Neurobiology (15-24). Springer. https://doi.org/10.1385/0-89603-199-3%3A15

Generally, genomic DNA is used either for the construction of genomic libraries or for Southern blot analysis. For several reasons, it is frequently preferable in the field of invertebrate neurobiology to screen, at least initially, genomic rather th... Read More about The Isolation of Genomic DNA from Invertebrates.

The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies (1989)
Book Chapter
Darlison, M. G., Barnard, E. A., Bateson, A. N., Glencorse, T. A., Harvey, R. J., Hicks, A. A., Hunt, S. P., Morris, B. J., Vallejo, M., Vreugdenhil, E., & Wisden, W. (1989). The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies. In Molecular Biology of Neuroreceptors and Ion Channels (83-99). Springer. https://doi.org/10.1007/978-3-642-74155-5_7

It is well established that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) mediates many of its effects by binding to the GABAA receptor, which is present on the majority of mammalian brain neurons (Enna, 1983), resulting in the opening o... Read More about The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies.

Molecular Biology of Nicotinic Acetylcholine Receptors from Chicken Muscle and Brain (1986)
Book Chapter
Squire, M. D., Moss, S. J., Lai, F. A., Darlison, M. G., Cockcroft, V. B., Barnard, E. A., Beeson, D. M. W., Hicks, A. A., Darlison, M. G., & Ross, S. J. (1986). Molecular Biology of Nicotinic Acetylcholine Receptors from Chicken Muscle and Brain. In A. Maelicke (Ed.), Nicotinic Acetylcholine Receptor (389-415). Springer. https://doi.org/10.1007/978-3-642-71649-2_30

While it has been completely established that the AChR** as isolated from the electroplaques of electric fish is composed of four different polypeptides, such that its subunit structure is α2βγδ (as reviewed in detail elsewhere in this Volume), the e... Read More about Molecular Biology of Nicotinic Acetylcholine Receptors from Chicken Muscle and Brain.