Uncovering novel effectors of Nrf2 dysregulation in the progression of Alzheimer's Disease May 12, 2020 - Dec 31, 2021
Nrf2 activators show pre-clinical promise in the treatment of several neurodegenerative diseases, including Alzheimer’s disease (AD), but exert clinical toxicity. Nrf2 regulates hundreds of anti-oxidant response element (ARE)-containing genes, but th...
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Projects (3)
Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease. Feb 14, 2022 - Nov 13, 2023
Lactoferrin (LF) is a glycoprotein which is widely contained in many secretory fluids, mainly milk but also saliva, tears, and nasal secretions. Many scientific reports supported an application of this glycoprotein in the prophylaxis and treatment of...
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Developing an adoptive regulatory T cell therapy for the treatment of rheumatoid arthritis Mar 1, 2021 - Feb 28, 2024
The immune system contains a balance of cells that turn responses ‘on’ and those that turn it ‘off’. When this balance breaks down, inappropriate immune responses can attack healthy tissues causing autoimmune disease, such as rheuma...
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