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The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium (2010)
Journal Article
Barlow, P. G., Beaumont, P. E., Cosseau, C., Mackellar, A., Wilkinson, T. S., Hancock, R. E. W., …Davidson, D. J. (2010). The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium. American Journal of Respiratory Cell

Cationic host defense peptides are key, evolutionarily conserved components of the innate immune system. The human cathelicidin LL-37 is an important cationic host defense peptide up-regulated in infection and inflammation, specifically in the human... Read More about The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium.

The impact of assuming the primary caregiver role following traumatic spinal cord injury: an interpretative phenomenological analysis of the spouse's experience. (2010)
Journal Article
Dickson, A., O'Brien, G., Ward, R., Allan, D., & O'Carroll, R. E. (2010). The impact of assuming the primary caregiver role following traumatic spinal cord injury: an interpretative phenomenological analysis of the spouse's experience. Psychology and Health, 25(9), 1101-1120. https://doi.org/10.1080/08870440903038949

This study aimed to explore the lived experience of assuming the primary caregiver role in a group of spouses of individuals living with a traumatic spinal cord injury (SCI) (injuries ranged from paraplegia to quadriplegia). Individual in-depth inter... Read More about The impact of assuming the primary caregiver role following traumatic spinal cord injury: an interpretative phenomenological analysis of the spouse's experience..

Oral versus written assessments: a test of student performance and attitudes (2010)
Journal Article
Huxham, M., Campbell, F., & Westwood, J. (2012). Oral versus written assessments: a test of student performance and attitudes. Assessment and Evaluation in Higher Education, 37(1), 125-136. https://doi.org/10.1080/02602938.2010.515012

Student performance in and attitudes towards oral and written assessments were compared using quantitative and qualitative methods. Two separate cohorts of students were examined. The first larger cohort of students (n = 99) was randomly divided into... Read More about Oral versus written assessments: a test of student performance and attitudes.

Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway (2010)
Journal Article
Hupp, T., Lin, Y., Henderson, P., Pettersson, S., Satsangi, J., Hupp, T. R., & Stevens, C. (2010). Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway. FEBS Journ

We previously identified a novel interaction between tuberous sclerosis-2 (TSC2) and death-associated protein kinase-1 (DAPK), the consequence being that DAPK catalyses the inactivating phosphorylation of TSC2 to stimulate mammalian target of rapamyc... Read More about Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.

Physiological effects of temperature and a herbicide mixture on the soft-shell clam Mya arenaria (Mollusca, Bivalvia) (2010)
Journal Article
Greco, L., Pellerin, J., Capri, E., Garnerot, F., Louis, S., Fournier, M., …Couture, P. (2011). Physiological effects of temperature and a herbicide mixture on the soft-shell clam Mya arenaria (Mollusca, Bivalvia). Environmental Toxicology and Chemistry

The aim of the current study was to investigate effects of temperature and a mixture of herbicides on the physiological status of the bivalve Mya arenaria. Bivalves acclimated to two temperatures (7 and 18°C) were exposed for 28 d to 0.01 mg/L of a p... Read More about Physiological effects of temperature and a herbicide mixture on the soft-shell clam Mya arenaria (Mollusca, Bivalvia).

Queen pheromones: The chemical crown governing insect social life (2010)
Journal Article
Holman, L. (2010). Queen pheromones: The chemical crown governing insect social life. Communicative and Integrative Biology, 3(6), 558-560. https://doi.org/10.4161/cib.3.6.12976

Group-living species produce signals that alter the behavior and even the physiology of their social partners. Social insects possess especially sophisticated chemical communication systems that govern every aspect of colony life, including the defin... Read More about Queen pheromones: The chemical crown governing insect social life.

Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infection (2010)
Journal Article
Campbell, S. A., Henriquez, F. L., Campbell, S. A., Roberts, C. W., Mullen, A. B., Burchmore, R., & Carter, K. C. (2010). Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infect

Visceral leishmaniasis presents a serious health threat in many parts of the world. There is, therefore, an urgent need for an approved vaccine for clinical use to protect against infection. In this study, the ability of recombinant Leishmania donova... Read More about Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infection.

The medium makes the message: Effects of cues on students' lecture notes (2010)
Journal Article
Huxham, M. (2010). The medium makes the message: Effects of cues on students' lecture notes. Active learning in higher education, 11(3), 179-188. https://doi.org/10.1177/1469787410379681

Previous work has shown that students’ notes often fail to record key facts and concepts. The relatively recent widespread adoption of PowerPoint slides and handouts might now help students to record key issues, but only if they can recognize the cue... Read More about The medium makes the message: Effects of cues on students' lecture notes.

The effect of sewage discharge on the ecosystem engineering activities of two East African fiddler crab species: Consequences for mangrove ecosystem functioning (2010)
Journal Article
Bartolini, F., Cimò, F., Fusi, M., Dahdouh-Guebas, F., Lopes, G. P., & Cannicci, S. (2011). The effect of sewage discharge on the ecosystem engineering activities of two East African fiddler crab species: Consequences for mangrove ecosystem functioning.

A number of studies have suggested that mangrove forests and their faunal components may be pre-adapted to the impact of organic waste discharge, making them possible natural wastewater treatment wetlands. However, the results from recent research ar... Read More about The effect of sewage discharge on the ecosystem engineering activities of two East African fiddler crab species: Consequences for mangrove ecosystem functioning.

Children with autism's perception and understanding of ambiguous figures: Evidence for pictorial metarepresentation, a research note (2010)
Journal Article
Wimmer, M. C., & Doherty, M. J. (2010). Children with autism's perception and understanding of ambiguous figures: Evidence for pictorial metarepresentation, a research note. British Journal of Developmental Psychology, 28(3), 627-641. https://doi.org/10.1

A large body of autism research over the last 20 years has shown that people with autism have difficulties understanding mental states. This has been conceived of as a metarepresentational deficit. An open question is whether people with autism's met... Read More about Children with autism's perception and understanding of ambiguous figures: Evidence for pictorial metarepresentation, a research note.

Effects of ozone exposure on the xerophilic fungus, Eurotium amstelodami IS-SAB-01, isolated from naan bread (2010)
Journal Article
Antony-Babu, S., & Singleton, I. (2011). Effects of ozone exposure on the xerophilic fungus, Eurotium amstelodami IS-SAB-01, isolated from naan bread. International Journal of Food Microbiology, 144(3), 331-336. https://doi.org/10.1016/j.ijfoodmicro.2010.

Xerophilic moulds cause contamination and spoilage of low moisture foods. This study examined the effect of ozone fumigation on growth of a Eurotium species isolated from naan bread. Two ozone treatments were used — a low-level long-term exposure (0.... Read More about Effects of ozone exposure on the xerophilic fungus, Eurotium amstelodami IS-SAB-01, isolated from naan bread.

Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task (2010)
Journal Article
Simpson, R. J., Graham, S. M., Florida-James, G. D., Connaboy, C., Clement, R., & Jackson, A. S. (2010). Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task. Applied

Identifying field measures to estimate backpack load-carriage work intensity in elite soldiers is of interest to the military. This study developed rating of perceived exertion (RPE) and heart rate models to define metabolic workload for a backpack l... Read More about Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task.

Chlamydia trachomatis infection increases fallopian tube PROKR2 via TLR2 and NFκB activation resulting in a microenvironment predisposed to ectopic pregnancy (2010)
Journal Article
Shaw, J. L. V., Wills, G. S., Lee, K., Horner, P. J., McClure, M. O., Abrahams, V. M., …Horne, A. W. (2011). Chlamydia trachomatis infection increases fallopian tube PROKR2 via TLR2 and NFκB activation resulting in a microenvironment predisposed to ect

Chlamydia trachomatis and smoking are major risk factors for tubal ectopic pregnancy (EP), but the underlying mechanisms of these associations are not completely understood. Fallopian tube (FT) from women with EP exhibit altered expression of prokine... Read More about Chlamydia trachomatis infection increases fallopian tube PROKR2 via TLR2 and NFκB activation resulting in a microenvironment predisposed to ectopic pregnancy.

A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice (2010)
Journal Article
Steitz, J., Barlow, P. G., Hossain, J., Kim, E., Okada, K., Kenniston, T., …Gambotto, A. (2010). A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice. PLOS ONE, 5(5), Article e10492. https://doi.org/10.1371/journal.pone.001049

Background In 2009 a new pandemic disease appeared and spread globally. The recent emergence of the pandemic influenza virus H1N1 first isolated in Mexico and USA raised concerns about vaccine availability. We here report our development of an adeno... Read More about A Candidate H1N1 Pandemic Influenza Vaccine Elicits Protective Immunity in Mice.

Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles (2010)
Journal Article
Song, J., Kim, Y., Barlow, P. G., Hossain, M. J., Park, K., Donis, R. O., …Kang, S. (2010). Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles. Antiviral Research, 88(2), 2

To develop a more effective vaccination method against H5N1 virus, we investigated the immunogenicity and protective efficacy after skin vaccination using microneedles coated with influenza virus-like particles containing hemagglutinin derived from A... Read More about Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles.

Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression (2010)
Journal Article
Fitch, P., Wheelhouse, N., Bowles, P., Paterson, M., Longbottom, D., Entrican, G., & Howie, S. (2010). Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression. Clinical and Experimental Immunology, 162(2), 372-378. https://doi.org/10.1111/j.1365-2249.2010.04231.x

Infection with Chlamydia pneumoniae (Cp) accounts for around 10% of community acquired bacterial pneumonia and has been associated with other chronic inflammatory conditions. We describe a C57/Bl6 murine model of Cp lung infection characterized by a... Read More about Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression.

The analysis of glycosylation: a continued need for high pH anion exchangechromatography (2010)
Journal Article
Behan, J. L., & Smith, K. D. (2011). The analysis of glycosylation: a continued need for high pH anion exchangechromatography. Biomedical Chromatography, 25(1-2 Special Issue: Silver Jubilee Special Issue & Special Reviews Issue: Bioanalysis of Drugs and

An appreciation of the structures of the oligosaccharide chains which become attached to biomolecules (the process known as glycosylation), and their relevance to the biological function of the molecule concerned, has progressed rapidly in recent y... Read More about The analysis of glycosylation: a continued need for high pH anion exchangechromatography.

Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease (2010)
Journal Article
Sofola, O., Kerr, F., Rogers, I., Killick, R., Augustin, H., Gandy, C., Allen, M. J., Hardy, J., Lovestone, S., & Partridge, L. (2010). Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease. PLoS Genetics,

Aβ peptide accumulation is thought to be the primary event in the pathogenesis of Alzheimer's disease (AD), with downstream neurotoxic effects including the hyperphosphorylation of tau protein. Glycogen synthase kinase-3 (GSK-3) is increasingly impli... Read More about Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease.