All Outputs (82)

Population level effects of intersexuality in the marine environment. (2007)
Journal Article
Ford, A. T., Martins, I., & Fernandes, T. (2007). Population level effects of intersexuality in the marine environment. Science of the Total Environment, 374, 102-111. https://doi.org/10.1016/j.scitotenv.2006.12.046

Whilst there have been many studies indicating links between anthropogenic contaminants and reproductive abnormalities in wildlife, very few studies have addressed the effects that might be occurring at the population level. In this study we aimed to... Read More about Population level effects of intersexuality in the marine environment..

“Hail brither Scots O’ Coaly Tyne”: networking and identity among Scottish migrants in the north east of England, ca.1860 – 2000. (2007)
Journal Article
Burnett, J. (2007). “Hail brither Scots O’ Coaly Tyne”: networking and identity among Scottish migrants in the north east of England, ca.1860 – 2000. Immigrants and Minorities, 25, 1-21. https://doi.org/10.1080/02619280701630870

Despite their significant presence throughout the modern era, Scottish emigrants to England have been neglected as a topic of research. At various times, Scottish in-migration to the north-east of England was greater than any other English region bot... Read More about “Hail brither Scots O’ Coaly Tyne”: networking and identity among Scottish migrants in the north east of England, ca.1860 – 2000..

The relative importance of external and internal features of facial composites (2007)
Journal Article
Frowd, C., Bruce, V., McIntyre, A., & Hancock, P. (2007). The relative importance of external and internal features of facial composites. British Journal of Psychology, 98(1), 61-77. doi:10.1348/000712606x104481

Three experiments are reported that compare the quality of external with internal regions within a set of facial composites using two matching-type tasks. Composites are constructed with the aim of triggering recognition from people familiar with the... Read More about The relative importance of external and internal features of facial composites.

Characterisation of a glucose phosphotransferase system in Clostridium acetobutylicum ATCC 824. (2007)
Journal Article
Tangney, M., & Mitchell, W. J. (2007). Characterisation of a glucose phosphotransferase system in Clostridium acetobutylicum ATCC 824. Applied microbiology and biotechnology, 74, 398-405. doi:10.1007/s00253-006-0679-9

The transport of glucose by the solventogenic anaerobe Clostridium acetobutylicum was investigated. Glucose phosphoenolpyruvate (PEP)-dependent phosphotransferase system (PTS) activity was detected in extracts prepared from cultures grown on glucose... Read More about Characterisation of a glucose phosphotransferase system in Clostridium acetobutylicum ATCC 824..

Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. (2007)
Journal Article
Lin, Y., Stevens, C., & Hupp, T. (2007). Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. Journal of Biological Chemistry, 282(23), 16792-16802. https://doi.org/10.1074/jbc.M611559200

DAPK-1 is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. To define mechanisms of DAPK-1 protein regulation, we have determined that DAPK-1 protein has a long half-life... Read More about Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis..

Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial (2007)
Journal Article
Mutrie, N., Campbell, A. M., Whyte, F., McConnachie, A., Emslie, C., Lee, L., Kearney, N., Walker, A., & Ritchie, D. (2007). Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial. BMJ, 334(7592), 517. https://doi.org/10.1136/bmj.39094.648553.ae

Objectives To determine functional and psychological benefits of a 12 week supervised group exercise programme during treatment for early stage breast cancer, with six month follow-up.Design Pragmatic randomised controlled prospective open trial.Sett... Read More about Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial.

Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity (2007)
Journal Article
Fraser, J. A., & Hupp, T. R. (2007). Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity. Biochemistry, 46(10), 2655-2673. https://doi.org/10.1021/bi061562j

Dissection of signal transduction pathways has been advanced by classic genetic approaches including targeted gene deletion and siRNA-based inhibition of gene product synthesis. Chemical genetics is a biochemical approach to develop small peptide-mim... Read More about Chemical Genetics Approach to Identify Peptide Ligands that Selectively Stimulate DAPK-1 Kinase Activity.

Devising and evaluating a model for teaching therapeutic handling and moving skills to complementary therapists (2007)
Journal Article
Donnelly, C., & MacMillan, M. S. (2007). Devising and evaluating a model for teaching therapeutic handling and moving skills to complementary therapists. Complementary Therapies in Clinical Practice, 13(3), 201-209. https://doi.org/10.1016/j.ctcp.2006.12.002

This two phase, mixed methods study, developed and evaluated the effectiveness of a model for teaching the neuromuscular approach (NMA) to human movement. From an original volunteer sample of 74 students, 33 completed the 15-week (Phase 1) moving and... Read More about Devising and evaluating a model for teaching therapeutic handling and moving skills to complementary therapists.

Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce (2007)
Journal Article
Tzortzakis, N., Singleton, I., & Barnes, J. (2007). Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce. Postharvest Biology and Technology, 43(2), 261-270. https://doi.org/10.1016/j.postharvbio.2006.09.005

Tomatoes, strawberries, table grapes and plums were inoculated with Botrytis cinerea (grey mould), transferred to chilled storage (13 °C) and exposed to ‘clean air’ or low-level ozone-enrichment (0.1 μmol mol−1). Ozone-enrichment resulted in a substa... Read More about Deployment of low-level ozone-enrichment for the preservation of chilled fresh produce.

A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis (2007)
Journal Article
Stevens, C., Lin, Y., Sanchez, M., Amin, E., Copson, E., White, H., Durston, V., Eccles, D. M., & Hupp, T. (2007). A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis. Journal of Biological Chemistry, 282(18), 13791-13803. https://doi.org/10.1074/jbc.m605649200

p53 is activated genetically by a set of kinases that are components of the calcium calmodulin kinase superfamily, including CHK2, AMP kinase, and DAPK-1. In dissecting the mechanism of DAPK-1 control, a novel mutation (N1347S) was identified in the... Read More about A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis.

Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS) (2007)
Journal Article
Hua, G., Broderick, J., Semple, K. T., Killham, K., & Singleton, I. (2007). Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS). Environmental Pollution, 148(1), 176-181. https://doi.org/10.1016/j.envpol.2006.10.040

Synchronous fluorescence spectroscopy (SFS) was directly applied to rapidly quantify selected polycyclic aromatic hydrocarbons (PAHs: benzo[a]pyrene and pyrene) in aqueous hydroxypropyl-β-cyclodextrin (HPCD) soil extract solutions from a variety of a... Read More about Rapid quantification of polycyclic aromatic hydrocarbons in hydroxypropyl-β-cyclodextrin (HPCD) soil extracts by synchronous fluorescence spectroscopy (SFS).

Carbon stable isotopes in estuarine sediments and their utility as migration markers for nursery studies in the Firth of Forth and Forth Estuary, Scotland (2007)
Journal Article
Augley, J., Huxham, M., Fernandes, T. F., Lyndon, A. R., & Bury, S. (2007). Carbon stable isotopes in estuarine sediments and their utility as migration markers for nursery studies in the Firth of Forth and Forth Estuary, Scotland. Estuarine, Coastal and Shelf Science, 72(4), (648-656). doi:10.1016/j.ecss.2006.11.024. ISSN 0272-7714

The stable carbon isotope ratios (δ13C) of the organic fraction of intertidal sediments in the Forth Estuary and the Firth of Forth, Scotland, were measured to determine if terrestrially derived carbon was present in the estuarine sediments. It was h... Read More about Carbon stable isotopes in estuarine sediments and their utility as migration markers for nursery studies in the Firth of Forth and Forth Estuary, Scotland.

Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence (2007)
Journal Article
Bennett, H. J., Pearce, D. M., Glenn, S., Taylor, C. M., Kuhn, M., Sonenshein, A. L., Andrew, P. W., & Roberts, I. S. (2007). Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence. Molecular Microbiology, 63(5), 1453-1467. https://doi.org/10.1111/j.1365-2958.2007.05597.x

Listeria monocytogenes is a Gram-positive intracellular parasite and the causative organism of human listeriosis. In this article we demonstrate that L. monocytogenes encodes a functional member of the CodY family of global regulatory proteins that i... Read More about Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence.

The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4 (2007)
Journal Article
Brown, D. M., Hutchison, L., Donaldson, K., MacKenzie, S., Dick, C., & Stone, V. (2007). The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4. Toxicology Letters, 168(1), 1-6. https://doi.org/10.1016/j.toxlet.2006.10.016

Reactive oxygen species (ROS) have been implicated in various pulmonary diseases by causing direct injury to lung epithelial cells. Signalling activity of cells through transcription factors such as nuclear factor kappa B (NF-κB) and AP-1 have been s... Read More about The effect of oxidative stress on macrophages and lung epithelial cells: The role of phosphodiesterases 1 and 4.

Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella (2007)
Journal Article
Nayeem, N., Kerr, F., Naumann, H., Linehan, J., Lovestone, S., & Brandner, S. (2007). Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella. Molecular and Cellular Neuroscience, 34(3), 400-408. https://doi.org/10.1016/j.mcn.2006.11.014

Inherited mutations to the tumor suppressor PTEN sporadically lead to cerebellar gangliocytoma characterized by migration defects. This has been modeled by CNS-specific PTEN ablation in mice, but the underlying mechanism cannot be explained by the kn... Read More about Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella.

Supplementary biochemical tests useful for the differentiation of oxidase positive staphylococci (2007)
Journal Article
Stepanović, S., Dakić, I., Hauschild, T., Vuković, D., Morrison, D., Ježek, P., Ćirković, I., & Petráš, P. (2007). Supplementary biochemical tests useful for the differentiation of oxidase positive staphylococci. Systematic and Applied Microbiology, 30(4), 316-318. https://doi.org/10.1016/j.syapm.2006.11.002

Differentiation of the oxidase positive staphylococci, Staphylococcus sciuri, Staphylococcus lentus, Staphylococcus vitulinus and Staphylococcus fleurettii, based on tributyrin, urease, caseinase, gelatinase and DNase activity is described. These tes... Read More about Supplementary biochemical tests useful for the differentiation of oxidase positive staphylococci.

Defining and detecting undesirable disturbance in the context of eutrophication. (2007)
Journal Article
Tett, P., Gowen, R. J., Mills, D., Fernandes, T., Gilpin, L., Huxham, M., …Malcolm, S. J. (2007). Defining and detecting undesirable disturbance in the context of eutrophication. Marine Pollution Bulletin, 55, 282-297. doi:10.1016/j.marpolbul.2006.08.028

An understanding of undesirable disturbance to the balance of organisms is needed to diagnose marine eutrophication as defined by EU Directives and OSPAR. This review summarizes the findings of the UK Defra-funded Undesirable Disturbance Study Team,... Read More about Defining and detecting undesirable disturbance in the context of eutrophication..

Performance, importance and user disgruntlement: a six-step method for measuring satisfaction with travel modes. (2007)
Journal Article
Stradling, S. G., Anable, J., & Carreno, M. (2007). Performance, importance and user disgruntlement: a six-step method for measuring satisfaction with travel modes. Transportation Research Part A: Policy and Practice, 41, 98-106. doi:10.1016/j.tra.2006.05.013

The technique described in this paper builds on work in the customer service literature on the measurement of customer dissatisfaction to develop a new way of combining measures of performance (how well is this aspect of a service being delivered?) a... Read More about Performance, importance and user disgruntlement: a six-step method for measuring satisfaction with travel modes..

The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. (2007)
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Middleton, N., Shave, R., George, K., & Guy, K. (2007). The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. European Journal of Applied Physiology, 99, 201-204. https://doi.org/10.1007/s00421-006-0326-2

Exercise is known to result in the haemolysis of red blood cells (RBCs). Although mechanical stressors such as footstrike and an increased velocity of blood flow may be involved, the biological mechanisms that underpin RBC haemolysis remain elusive.... Read More about The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells..

Thyroid hormone signaling in human ovarian surface epithelial cells. (2007)
Journal Article
Rae, M. T., Gubbay, O., NaKostogiannou, A., Price, D., Critchley, H. O. D., & Hillier, S. G. (2007). Thyroid hormone signaling in human ovarian surface epithelial cells. Journal of Clinical Endocrinology and Metabolism, 92, 322-327. doi:10.1210/jc.2006-1522

Ovarian surface epithelial (OSE) cells express multiple nuclear hormone receptor genes, including those encoding thyroid hormone and estrogen receptors (TR and ER, respectively). Ovarian cancer is hormone-dependent, and epidemiological evidence links... Read More about Thyroid hormone signaling in human ovarian surface epithelial cells..