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All Outputs (258)

Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age (2021)
Journal Article
Lithgow, H., Florida‐James, G., Ross, M., Duncan, G., & Leggate, M. (2021). Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age. Experimental Physiology, 106(7), 1460-1469. https://doi.org/10.1113/ep089480

Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activity and availability of the VDR. This study aimed to investigate the effect... Read More about Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age.

‘It maybe doesn’t seem much, but to me it’s my kingdom’: staff and client experiences of Housing First in Scotland (2021)
Journal Article
Miler, J. A., Foster, R., Hnizdilova, K., Murdoch, H., & Parkes, T. (2022). ‘It maybe doesn’t seem much, but to me it’s my kingdom’: staff and client experiences of Housing First in Scotland. Drugs: Education, Prevention, and Policy, 29(3), 231-244. https://doi.org/10.1080/09687637.2021.1926429

Housing First (HF) represents a significant shift in the way that the problem of homelessness and co-occuring challenges including problem substance use, is addressed. HF interventions have been the focus of much research. Quantitative studies have c... Read More about ‘It maybe doesn’t seem much, but to me it’s my kingdom’: staff and client experiences of Housing First in Scotland.

Adaptation to one perceived motion direction can generate multiple velocity aftereffects (2021)
Journal Article
Gekas, N., & Mamassian, P. (2021). Adaptation to one perceived motion direction can generate multiple velocity aftereffects. Journal of Vision, 21(5), Article 17. https://doi.org/10.1167/jov.21.5.17

Sensory adaptation is a useful tool to identify the links between perceptual effects and neural mechanisms. Even though motion adaptation is one of the earliest and most documented aftereffects, few studies have investigated the perception of directi... Read More about Adaptation to one perceived motion direction can generate multiple velocity aftereffects.

The impact of medication side effects on adherence and persistence to hormone therapy in breast cancer survivors: A qualitative systematic review and thematic synthesis (2021)
Journal Article
Peddie, N., Agnew, S., Crawford, M., Dixon, D., MacPherson, I., & Fleming, L. (2021). The impact of medication side effects on adherence and persistence to hormone therapy in breast cancer survivors: A qualitative systematic review and thematic synthesis. The Breast, 58, 147-159. https://doi.org/10.1016/j.breast.2021.05.005

Background Hormone Therapy (HT) reduces the risk of breast cancer recurrence and mortality in women with breast cancer. Despite these clinical benefits, rates of HT non-adherence and non-persistence are high. Research suggests this may be due to the... Read More about The impact of medication side effects on adherence and persistence to hormone therapy in breast cancer survivors: A qualitative systematic review and thematic synthesis.

Using behavioural theory to understand adherence to behaviours that reduce transmission of COVID‐19; evidence from the CHARIS representative national study (2021)
Journal Article
Dixon, D., Den Daas, C., Hubbard, G., & Johnston, M. (2022). Using behavioural theory to understand adherence to behaviours that reduce transmission of COVID‐19; evidence from the CHARIS representative national study. British Journal of Health Psychology, 27(1), 116-135. https://doi.org/10.1111/bjhp.12533

Objectives To examine the ability of four models of behaviour, namely, Protection Motivation Theory (PMT), the Common Sense Self-Regulation Model (CS-SRM), and Social Cognitive Theory and the Reasoned Action Approach (SCT and RAA) to understand adhe... Read More about Using behavioural theory to understand adherence to behaviours that reduce transmission of COVID‐19; evidence from the CHARIS representative national study.

Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity (2021)
Journal Article
Abdel-Maksoud, M. S., El-Gamal, M. I., Lee, B. S., Gamal El-Din, M. M., Jeon, H. R., Kwon, D., Ammar, U. M., Mersal, K. I., Ali, E. M. H., Lee, K., Yoo, K. H., Han, D. K., Lee, J. K., Kim, G., Choi, H. S., Kwon, Y. J., Lee, K. H., & Oh, C. H. (2021). Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity. Journal of Medicinal Chemistry, 64(10), 6877-6901. https://doi.org/10.1021/acs.jmedchem.1c00230

BRAF is an important component of MAPK cascade. Mutation of BRAF, in particular V600E, leads to hyperactivation of the MAPK pathway and uncontrolled cellular growth. Resistance to selective inhibitors of mutated BRAF is a major obstacle against treat... Read More about Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity.

A paradigm shift to combat indoor respiratory infection (2021)
Journal Article
Morawska, L., Allen, J., Bahnfleth, W., Bluyssen, P. M., Boerstra, A., Buonanno, G., …Yao, M. (2021). A paradigm shift to combat indoor respiratory infection. Science, 372(6543), 689-691. https://doi.org/10.1126/science.abg2025

There is great disparity in the way we think about and address different sources of environmental infection. Governments have for decades promulgated a large amount of legislation and invested heavily in food safety, sanitation, and drinking water fo... Read More about A paradigm shift to combat indoor respiratory infection.

Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi) (2021)
Book Chapter
Donnellan, S., Martínez-Rodríguez, C., Aljayyoussi, G., & Biagini, G. A. (2021). Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi). In C. Barreiro, & J. Barredo (Eds.), Antimicrobial Therapies: Methods and Protocols (393-408). Humana Press. https://doi.org/10.1007/978-1-0716-1358-0

The human disease tuberculosis (TB) is the leading cause of death from a single infectious agent. A quarter of the world’s population is estimated to be latently infected. Drug development and screening is slow and costly. We have developed a physiol... Read More about Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi).

From theory to practice in pattern‐oriented modelling: identifying and using empirical patterns in predictive models (2021)
Journal Article
Gallagher, C. A., Chudzinska, M., Larsen‐Gray, A., Pollock, C. J., Sells, S. N., White, P. J. C., & Berger, U. (2021). From theory to practice in pattern‐oriented modelling: identifying and using empirical patterns in predictive models. Biological Reviews, 96(5), 1868-1888. https://doi.org/10.1111/brv.12729

To robustly predict the effects of disturbance and ecosystem changes on species, it is necessary to produce structurally realistic models with high predictive power and flexibility. To ensure that these models reflect the natural conditions necessary... Read More about From theory to practice in pattern‐oriented modelling: identifying and using empirical patterns in predictive models.

Compartmentalization of bacterial and fungal microbiomes in the gut of adult honeybees (2021)
Journal Article
Callegari, M., Crotti, E., Fusi, M., Marasco, R., Gonella, E., De Noni, I., Romano, D., Borin, S., Tsiamis, G., Cherif, A., Alma, A., & Daffonchio, D. (2021). Compartmentalization of bacterial and fungal microbiomes in the gut of adult honeybees. npj Biofilms and Microbiomes, 7, Article 42. https://doi.org/10.1038/s41522-021-00212-9

The core gut microbiome of adult honeybee comprises a set of recurring bacterial phylotypes, accompanied by lineage-specific, variable, and less abundant environmental bacterial phylotypes. Several mutual interactions and functional services to the h... Read More about Compartmentalization of bacterial and fungal microbiomes in the gut of adult honeybees.

Discursive representations of restorative justice in international policies (2021)
Journal Article
Pali, B., & Maglione, G. (2023). Discursive representations of restorative justice in international policies. European Journal of Criminology, 20(2), 507-527. https://doi.org/10.1177/14773708211013025

The European Directive 2012/29/EU, the Council of Europe Recommendation CM/Rec(2018)8), and the recently launched updated United Nations Handbook (2020) testify to the increasing policy recognition of restorative justice at international level. And y... Read More about Discursive representations of restorative justice in international policies.

What is the relationship between indoor air quality parameters and airborne microorganisms in hospital environments? A systematic review and meta‐analysis (2021)
Journal Article
Hiwar, W., King, M., Shuweihdi, F., Fletcher, L. A., Dancer, S. J., & Noakes, C. J. (2021). What is the relationship between indoor air quality parameters and airborne microorganisms in hospital environments? A systematic review and meta‐analysis. Indoor Air, 31(5), 1308-1322. https://doi.org/10.1111/ina.12846

Airborne microorganisms in hospitals have been associated with several hospital‐acquired infections (HAIs), and various measures of indoor air quality (IAQ) parameters such as temperature, relative humidity, carbon dioxide (CO2), particle mass concen... Read More about What is the relationship between indoor air quality parameters and airborne microorganisms in hospital environments? A systematic review and meta‐analysis.

Verdict spotting: Investigating the effects of juror bias, evidence anchors, and verdict system in jurors (2021)
Journal Article
Curley, L. J., Murray, J., MacLean, R., Munro, J., Lages, M., Frumkin, L. A., Laybourn, P., & Brown, D. (2022). Verdict spotting: Investigating the effects of juror bias, evidence anchors, and verdict system in jurors. Psychiatry, Psychology and Law, 29(3), 323-344. https://doi.org/10.1080/13218719.2021.1904450

The Scottish verdict of not proven represents a second acquittal verdict which is not legally defined. Existing research into the influence of the not proven verdict on jury decision making is modest. The main aim of the current study was therefore t... Read More about Verdict spotting: Investigating the effects of juror bias, evidence anchors, and verdict system in jurors.

Camera trap photographs of mountain hare Lepus timidus per month Scotland (S1A) (2021)
Data
Gilchrist, J., Pettigrew, G., Di Vita, V., & Pettigrew, M. (2021). Camera trap photographs of mountain hare Lepus timidus per month Scotland (S1A). [Dataset]. https://doi.org/10.5061/dryad.m0cfxpp3p

The research presented in this paper provides an insight into the behavioural ecology of mountain hares on heather moorland in the Lammermuir Hills of south east Scotland. We examine the seasonal and diel activity patterns using camera traps over a p... Read More about Camera trap photographs of mountain hare Lepus timidus per month Scotland (S1A).

Calculation of detection rate for camera trap records of mountain hare Lepus timidus Scotland (S2) (2021)
Data
Gilchrist, J., Pettigrew, G., Di Vita, V., & Pettigrew, M. (2021). Calculation of detection rate for camera trap records of mountain hare Lepus timidus Scotland (S2). [Dataset]. https://doi.org/10.5061/dryad.4b8gthtc4

The research presented in this paper provides an insight into the behavioural ecology of mountain hares on heather moorland in the Lammermuir Hills of south east Scotland. We examine the seasonal and diel activity patterns using camera traps over a p... Read More about Calculation of detection rate for camera trap records of mountain hare Lepus timidus Scotland (S2).

Calculation of times relative to sunset and sunrise for mountain hare Lepus timidus camera trap records Scotland (S1b) (2021)
Data
Gilchrist, J., Pettigrew, G., Di Vita, V., & Pettigrew, M. (2021). Calculation of times relative to sunset and sunrise for mountain hare Lepus timidus camera trap records Scotland (S1b). [Dataset]. https://doi.org/10.5061/dryad.2bvq83bpx

The research presented in this paper provides an insight into the behavioural ecology of mountain hares on heather moorland in the Lammermuir Hills of south east Scotland. We examine the seasonal and diel activity patterns using camera traps over a p... Read More about Calculation of times relative to sunset and sunrise for mountain hare Lepus timidus camera trap records Scotland (S1b).

The diel activity pattern of mountain hare (Lepus timidus) on managed heather moorland in Scotland (2021)
Journal Article
Pettigrew, G. W., Di Vita, V., Pettigrew, M., & Gilchrist, J. S. (2021). The diel activity pattern of mountain hare (Lepus timidus) on managed heather moorland in Scotland. Ecology and Evolution, 11(12), 7106-7113. https://doi.org/10.1002/ece3.7512

The research presented in this paper provides an insight into the behavioral ecology of mountain hares on heather moorland in the Lammermuir Hills of southeast Scotland. We examine the seasonal and diel activity patterns using camera traps over a per... Read More about The diel activity pattern of mountain hare (Lepus timidus) on managed heather moorland in Scotland.