All Outputs (36)

Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation (2024)
Journal Article
Albustami, M., Hartfiel, N., Charles, J. M., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., Hee, S. W., Banerjee, P., Ingle, L., Shave, R., Mcgregor, G., & Edwards, R. T. (2024). Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation. Archives of Physical Medicine and Rehabilitation, 105(4), 639-646. https://doi.org/10.1016/j.apmr.2023.09.005

Objective: To perform a cost-effectiveness analysis of high-intensity interval training (HIIT) compared with moderate intensity steady-state (MISS) training in people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). Design: S... Read More about Cost-effectiveness of High-Intensity Interval Training (HIIT) vs Moderate Intensity Steady-State (MISS) Training in UK Cardiac Rehabilitation.

Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLOS ONE, 19(3), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation (2023)
Journal Article
James, E., Butler, T., Nichols, S., Goodall, S., & O'Doherty, A. F. (2024). Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation. British Journal of Nutrition, 131(5), 880-893. https://doi.org/10.1017/s0007114523002374

Dietary education is a core component of cardiac rehabilitation (CR). It is unknown how or what dietary education is delivered across the UK. We aimed to characterise practitioners who deliver dietary education in UK CR and determine the format and c... Read More about Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation.

Remote ischaemic conditioning for fatigue after stroke (RICFAST): A pilot randomised controlled trial (2023)
Journal Article
Moyle, B., Kudiersky, N., Totton, N., Sassani, M., Nichols, S., Jenkins, T., Redgrave, J., Baig, S., Padmakumari, K., Nair, S., Majid, A., & Ali, A. N. (2023). Remote ischaemic conditioning for fatigue after stroke (RICFAST): A pilot randomised controlled trial. Journal of Stroke and Cerebrovascular Diseases, 32(12), Article 107420. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107420

Background: Post stroke fatigue (PSF) affects 50 % of stroke survivors, and can be disabling. Remote ischaemic conditioning (RIC), can preserve mitochondrial function, improve tissue perfusion and may mitigate PSF. This pilot randomised controlled tr... Read More about Remote ischaemic conditioning for fatigue after stroke (RICFAST): A pilot randomised controlled trial.

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER) (2023)
Journal Article
Ngaage, D. L., Mitchell, N., Dean, A., Mitchell, A., Hinde, S., Akowuah, E., Doherty, P., Nichols, S., Fairhurst, C., Flemming, K., Hewitt, C., Ingle, L., & Watson, J. (2023). A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and Feasibility Studies, 9(1), Article 79. https://doi.org/10.1186/s40814-023-01304-3

Objective
To determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial is achievable.... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER).

Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process (2023)
Journal Article
McHale, S., Cowie, A., Brown, S., Butler, T., Carver, K., Dalal, H. M., Dawkes, S., Deighan, C., Doherty, P., Evans, J., Hinton, S., Jones, J., Mills, J., Nichols, S., & Taylor, R. S. (2023). Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process. Open Heart, 10(1), Article e002248. https://doi.org/10.1136/openhrt-2022-002248

Objective: The purpose of this British Association for Cardiovascular Prevention and Rehabilitation (BACPR) research priority setting project (PSP) was to identify a top 10 list of priority research questions for cardiovascular prevention and rehabil... Read More about Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process.

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O'Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, Article 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial (2023)
Journal Article
McGregor, G., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., McGuire, S., Prosser, J., Fiassam, O., Hee, S. W., Hamborg, T., Banerjee, P., Hartfiel, N., Charles, J. M., Edwards, R. T., Drane, A., Ali, D., Osman, F., He, H., Lachlan, T., …Shave, R. (2023). High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European Journal of Preventive Cardiology, 30(9), 745-755. https://doi.org/10.1093/eurjpc/zwad039

Background
There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR).

Aims
To assess the clinical effectiv... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.

The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation (2022)
Journal Article
James, E., Oman, P., Ali, M., Court, P., Goodall, S., Nichols, S. J., & O'doherty, A. F. (2022). The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation. BMC Public Health, 22(1), Article 1457. https://doi.org/10.1186/s12889-022-13832-3

Background: Falls prevention exercise programmes are evidence-based and recommended for improving physical function in older adults. However, few service evaluations exist to assess the effectiveness of community-delivered interventions in practice.... Read More about The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation.

Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation (2021)
Journal Article
Frith, G., Carver, K., Curry, S., Darby, A., Sydes, A., Symonds, S., Wilson, K., Mcgregor, G., Auton, K., & Nichols, S. (2021). Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation. BMC Health Services Research, 21(1), Article 1363. https://doi.org/10.1186/s12913-021-07363-7

Background: Restrictions on face-to-face contact, due to COVID-19, led to a rapid adoption of technology to remotely deliver cardiac rehabilitation (CR). Some technologies, including Active + me, were used without knowing their benefits. We assessed... Read More about Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation.

Ratings of Perceived Exertion at the Ventilatory Anaerobic Threshold in People with Coronary Heart Disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of Perceived Exertion at the Ventilatory Anaerobic Threshold in People with Coronary Heart Disease: A CARE CR study. Annals of Physical and Rehabilitation Medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background
Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of Perceived Exertion at the Ventilatory Anaerobic Threshold in People with Coronary Heart Disease: A CARE CR study.

Effect of Exercise Interventions on Health-Related Quality of Life After Stroke and Transient Ischemic Attack: A Systematic Review and Meta-Analysis (2021)
Journal Article
Ali, A., Tabassum, D., Baig, S. S., Moyle, B., Redgrave, J., Nichols, S., McGregor, G., Evans, K., Totton, N., Cooper, C., & Majid, A. (2021). Effect of Exercise Interventions on Health-Related Quality of Life After Stroke and Transient Ischemic Attack: A Systematic Review and Meta-Analysis. Stroke, 52(7), 2445-2455. https://doi.org/10.1161/strokeaha.120.032979

Exercise interventions have been shown to help physical fitness, walking, and balance after stroke, but data are lacking on whether such interventions lead to improvements in health-related quality of life (HRQoL). In this systematic review and meta-... Read More about Effect of Exercise Interventions on Health-Related Quality of Life After Stroke and Transient Ischemic Attack: A Systematic Review and Meta-Analysis.

How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR (2021)
Journal Article
O'Doherty, A. F., Humphreys, H., Dawkes, S., Cowie, A., Hinton, S., Brubaker, P. H., Butler, T., & Nichols, S. (2023). How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR. BMJ Open, 11(4), Article e046051. https://doi.org/10.1136/bmjopen-2020-046051

Objective: To investigate whether exercise-based cardiac rehabilitation services continued during the COVID-19 pandemic and how technology has been used to deliver home-based cardiac rehabilitation.

Design: A mixed methods survey including questio... Read More about How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR.

The influence of resistance training on neuromuscular function in middle-aged and older adults: A systematic review and meta-analysis of randomised controlled trials. (2021)
Journal Article
James, E., Nichols, S., Goodall, S., Hicks, K. M., & O'doherty, A. F. (2021). The influence of resistance training on neuromuscular function in middle-aged and older adults: A systematic review and meta-analysis of randomised controlled trials. Experimental Gerontology, 149, Article 111320. https://doi.org/10.1016/j.exger.2021.111320

Background: Deterioration of neuromuscular function is a major mechanism of age-related strength loss. Resistance training (RT) improves muscle strength and mass. However, the effects of RT on neuromuscular adaptations in middle-aged and older adults... Read More about The influence of resistance training on neuromuscular function in middle-aged and older adults: A systematic review and meta-analysis of randomised controlled trials..

Exercise Training as a Mediator for Enhancing Coronary Collateral Circulation: A Review of the Evidence (2020)
Journal Article
Nickolay, T., Nichols, S., Ingle, L., & Hoye, A. (2020). Exercise Training as a Mediator for Enhancing Coronary Collateral Circulation: A Review of the Evidence. Current Cardiology Reviews, 16(3), 212-220. https://doi.org/10.2174/1573403x15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise Training as a Mediator for Enhancing Coronary Collateral Circulation: A Review of the Evidence.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2020)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (2020). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, 27(9), 1001–1003. https://doi.org/10.1177/2047487319856432

The metabolic equivalent (MET) is a widely used physiological concept for quantifying levels of habitual physical activity and cardiorespiratory fitness (CRF) by conveying oxygen consumption requirements of physical activities as multiples of resting... Read More about Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription.

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: A United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Lee, I. (2020). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: A United Kingdom-based community programme. PLOS ONE, 15(8), Article e0237197. https://doi.org/10.1371/journal.pone.0237197

Background

Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to charact... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: A United Kingdom-based community programme.

COVID-19 and cardiac rehabilitation (2020)
Journal Article
Dawkes, S., Hughes, S., Ray, S., Nichols, S., Hinton, S., Roberts, C., Butler, T., Hayes Dalal, D., & Docherty, P. (2020). COVID-19 and cardiac rehabilitation. British Journal of Cardiology, 27(2), 50. https://doi.org/10.5837/bjc.2020.019

The British Association for Cardiovascular Prevention and Rehabilitation (BACPR), the British Cardiovascular Society (BCS) and the British Heart Foundation (BHF) have issued a joint position statement ‘Retention of cardiac rehabilitation services dur... Read More about COVID-19 and cardiac rehabilitation.

Current Insights into Exercise-based Cardiac Rehabilitation in Patients with Coronary Heart Disease and Chronic Heart Failure (2020)
Journal Article
Nichols, S., McGregor, G., Breckon, J., & Ingle, L. (2021). Current Insights into Exercise-based Cardiac Rehabilitation in Patients with Coronary Heart Disease and Chronic Heart Failure. International Journal of Sports Medicine, 42(01), 19-26. https://doi.org/10.1055/a-1198-5573

Cardiac rehabilitation is a package of lifestyle secondary prevention strategies designed for patients with coronary heart disease and chronic heart failure. A community-based cardiac rehabilitation programme provides patients with a structured exerc... Read More about Current Insights into Exercise-based Cardiac Rehabilitation in Patients with Coronary Heart Disease and Chronic Heart Failure.

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective (2020)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (2020). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective. European Journal of Preventive Cardiology, 27(6), 579-589. https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve (%HRR)) in cardiac rehabilitation programmes. We aimed to determine the accuracy of this approach by comparing it with an obj... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective.