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All Outputs (29)

Longitudinal Induction to support transformative learning for international students undertaking a two-year MSc (2025)
Presentation / Conference Contribution
Campbell-Casey, S., & MacCallum, J. (2025, July). Longitudinal Induction to support transformative learning for international students undertaking a two-year MSc. Presented at Improving University Teaching Conference, University of Westminster, London

We have adapted an MSc programme for international students, to create a two-stage course, allowing for extended induction to key skills for success at level 11. The first year is at undergraduate level and is supported by academic support services a... Read More about Longitudinal Induction to support transformative learning for international students undertaking a two-year MSc.

Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome? (2024)
Presentation / Conference Contribution
Mincher, D., Kamel, M., Mohammed, O., MacCallum, J., & Turnbull, A. (2024, June). Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome?. Presented at EACR 2024: Innovative Cancer Science, Rotterdam, Netherlands

Introduction
Defining structural features that can control and pinpoint the delivery of drugs to specific sub-cellular organelles ofcancer cells offers the prospect of designing more potentand selective drugs that negate drug resistance, with less d... Read More about Design of new anticancer drugs by selectable intracellular organelle targeting: make for the mitochondria or turn left for the lysosome?.

Into the toxicity potential of an array of parabens by biomimetic liquid chromatography, cell viability assessments and in silico predictions (2024)
Journal Article
Neri, I., MacCallum, J., Di Lorenzo, R., Russo, G., Lynen, F., & Grumetto, L. (2024). Into the toxicity potential of an array of parabens by biomimetic liquid chromatography, cell viability assessments and in silico predictions. Science of the Total Environment, 917, Article 170461. https://doi.org/10.1016/j.scitotenv.2024.170461

Five parabens (PBs) i.e., Methylparaben (MP), Ethylparaben (EP), Isopropylparaben (iPrP), Isobutylparaben (iBuP), Benzylparaben (BzP), and their parent compound i.e., para–hydroxy Benzoic Acid (pHBA), were studied both in vitro and in silico. Specifi... Read More about Into the toxicity potential of an array of parabens by biomimetic liquid chromatography, cell viability assessments and in silico predictions.

Reflecting on the impacts of changes to teaching and support of the 2-stage 2-year MSc in Pharmaceutical and Analytical Science (2023)
Presentation / Conference Contribution
MacCallum, J., Foley, S., Arnott, I., & Oluwadare, T. (2023, June). Reflecting on the impacts of changes to teaching and support of the 2-stage 2-year MSc in Pharmaceutical and Analytical Science. Poster presented at The Gathering - Edinburgh Napier University L&T Conference, Edinburgh

Janis MacCallum, Sophie Foley, Iain Arnott, Tayo Oluwadare

The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption (2023)
Presentation / Conference Contribution
Dillon, A., Orzek, D., MacCallum, J., & Russo, G. (2023, June). The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption. Poster presented at HPLC 2023

Nowadays immobilized artificial membranes (IAM) are commonly used for modelling drug
transport through biological lipid layers. In most published studies a compound’s lipophilicity
measurements are performed in isocratic conditions where a low pe... Read More about The effectiveness of biomimetic chromatography based methods in predictions of human pulmonary drug absorption.

Meaningfully Embedding Industry-Relevant Life Science Skills in the Undergraduate Biosciences Curriculum (2023)
Presentation / Conference Contribution
Garden, C., Campbell Casey, S., & MacCallum, J. (2023, June). Meaningfully Embedding Industry-Relevant Life Science Skills in the Undergraduate Biosciences Curriculum. Presented at QAA Scotland's 5th International Enhancement Conference, Glasgow

For more than a decade I and colleagues have been working in partnership with the Scottish Lifesciences industry and other stakeholders to develop relevant, industry informed biosciences curricula at Edinburgh Napier University. This work has also be... Read More about Meaningfully Embedding Industry-Relevant Life Science Skills in the Undergraduate Biosciences Curriculum.

Researching skills development: students as partners in this process (2018)
Journal Article
Campbell Casey, S., MacCallum, J., Robertson, L., & Strachan, L. (2018). Researching skills development: students as partners in this process. New Directions in the Teaching of Physical Sciences, 13(1), https://doi.org/10.29311/ndtps.v0i13.2881

Many employers report that newly qualified graduates lack key skills necessary for success in the workplace. Although variable, many lack general ‘transferable’ or ‘soft’ skills including communication and teamworking. Staff at Edinburgh Napier Unive... Read More about Researching skills development: students as partners in this process.

Enhancing skills development and reflective practise in students during their programme of study (2017)
Journal Article
MacCallum, J., & Campbell Casey, S. (2017). Enhancing skills development and reflective practise in students during their programme of study. New Directions in the Teaching of Physical Sciences, 12(12), https://doi.org/10.29311/ndtps.v0i12.2368

The transition to the workplace can be challenging for new graduates. At Edinburgh Napier our approach is to work proactively with students to prepare them for the world of work. Staff within the School of Applied Sciences have partnered with both in... Read More about Enhancing skills development and reflective practise in students during their programme of study.

Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion (2016)
Journal Article
Ramaswamy, S., McNeilly, A. S., Rae, M. T., Ramaswamy, S., Grace, C., Mattei, A. A., Siemienowicz, K., Brownlee, W., MacCallum, J., McNeilly, A. S., Duncan, W. C., & Rae, M. T. (2016). Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion. Scientific Reports, 6(1), Article 27408. https://doi.org/10.1038/srep27408

Exogenous androgenic steroids applied to pregnant sheep programmes a PCOS-like phenotype in female offspring. Via ultrasound guidance we applied steroids directly to ovine fetuses at d62 and d82 of gestation, and examined fetal (day 90 gestation) and... Read More about Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion.

'Skills Passport' for Life Sciences at Edinburgh Napier University: Helping students to help themselves. (2015)
Presentation / Conference Contribution
Campbell, S. A., Durkin, P., MacCallum, J., & MacNab, A. (2015, June). 'Skills Passport' for Life Sciences at Edinburgh Napier University: Helping students to help themselves. Paper presented at QAA Enhancement and Innovation in Higher Education Conference

Developing graduates with the appropriate skills for future employment is an issue that affects every sector of industry. Research within the Life Sciences sector in Scotland has identified a number of areas where improvements could be made in the sk... Read More about 'Skills Passport' for Life Sciences at Edinburgh Napier University: Helping students to help themselves..

Audio feedback: richer language but no measurable impact on student performance (2014)
Journal Article
Chalmers, C., MacCallum, J., Mowat, E., & Fulton, N. (2014). Audio feedback: richer language but no measurable impact on student performance. Practitioner Research in Higher Education, 8, 64-73

Audio feedback has been shown to be popular and well received by students. However, there is little published work to indicate how effective audio feedback is in improving student performance.
Sixty students from a first year science degree agreed... Read More about Audio feedback: richer language but no measurable impact on student performance.

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS) (2013)
Journal Article
Franks, S., Rae, M. T., Grace, C., Hogg, K., Wilson, L. M., McHaffie, S. L., Ramaswamy, S., MacCallum, J., Connolly, F., McNeilly, A. S., & Duncan, C. (2013). The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS). PLOS ONE, 8(2), Article e56263. https://doi.org/10.1371/journal.pone.0056263

Using an ovine model of polycystic ovary syndrome (PCOS), (pregnant ewes injected with testosterone propionate (TP) (100 mg twice weekly) from day (d)62 to d102 of d147 gestation (maternal injection – MI-TP)), we previously reported female offspring... Read More about The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS).

Effect of Nippostrongylus brasiliensis L3 ES on inflammatory mediator gene transcription in lipopolysaccharide lung inflammation (2008)
Journal Article
Zhao, M., Brown, D. M., MacCallum, J., & Proudfoot, L. (2008). Effect of Nippostrongylus brasiliensis L3 ES on inflammatory mediator gene transcription in lipopolysaccharide lung inflammation. Parasite Immunology, 31(1), 50-56. https://doi.org/10.1111/j.1365-3024.2008.01073.x

The anti-inflammatory properties of parasitic helminths have been largely linked to their excretory-secretory (ES) products. Some studies have noted a lack of TNF-alpha production and limited recruitment of neutrophils into the lungs after Nippostron... Read More about Effect of Nippostrongylus brasiliensis L3 ES on inflammatory mediator gene transcription in lipopolysaccharide lung inflammation.

Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure (2007)
Journal Article
Barlow, P. G., Brown, D. M., Donaldson, K., MacCallum, J., & Stone, V. (2008). Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure. Cell Biology and Toxicology, 24(3), 243-252. https://doi.org/10.1007/s10565-007-9033-y

Increased levels of particulate air pollution (PM10) have been implicated as a causal agent in pulmonary disease exacerbation and increased deaths from respiratory and cardiovascular disorders. The exact mechanism by which PM10 drives toxicity in the... Read More about Reduced alveolar macrophage migration induced by acute ambient particle (PM10) exposure.

Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. (2005)
Journal Article
Barlow, P. G., Clouter-Baker, A., Donaldson, K., MacCallum, J., & Stone, V. (2005). Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Particle and fibre toxicology, 2(1), 11-24. https://doi.org/10.1186/1743-8977-2-11

Background - Alveolar macrophages are a key cell in dealing with particles deposited in the lungs and in determining the subsequent response to that particle exposure. Nanoparticles are considered a potential threat to the lungs and the mechanism of... Read More about Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages..

Ticks and Lyme Disease. (2004)
Journal Article
Chalmers, C., MacCallum, J., Brown, J., & Anderson, R. (2004). Ticks and Lyme Disease. Practice Nursing, 15,

Ticks are prevalent in parts of the UK during the summer months. Charlotte Chalmers, Janis MacCallum, Jane Brown and Ros Anderson discuss the associated diseases and recommend a method of removal.