Outputs (20)

An ultra-endurance event leads to changes in circulating regulatory T-cells, CD4+ naïve and CD8+ effector memory T-cells in the 48 h post-race recovery period (2024)
Journal Article
Lithgow, H., Gibson, L., Wilson, R., Guthrie, N., Ingram-Sills, L., Clifford, T., & Ross, M. (2025). An ultra-endurance event leads to changes in circulating regulatory T-cells, CD4+ naïve and CD8+ effector memory T-cells in the 48 h post-race recovery period. European Journal of Applied Physiology, 125(4), 1129-1138. https://doi.org/10.1007/s00421-024-05677-y

Purpose: Exercise is known to acutely affect T-lymphocyte populations in the peripheral blood, which is intensity- and duration-dependent. However, effects of longer duration endurance exercise (>5 h) on T-cells in the days following are unknown. The... Read More about An ultra-endurance event leads to changes in circulating regulatory T-cells, CD4+ naïve and CD8+ effector memory T-cells in the 48 h post-race recovery period.

The motivations, identities, and environmental sensibilities of contemporary e-mountain bike users (2024)
Book Chapter
Ingram-Sills, L. (2024). The motivations, identities, and environmental sensibilities of contemporary e-mountain bike users. In J. Cherrington (Ed.), Mountain Biking, Culture and Society. Routledge. https://doi.org/10.4324/9781003361626-5

During an era of rapid technological improvement, the demand for e-mountain biking is growing. Furthermore, an older demographic of rider participates in e-mountain biking in comparison to traditional mountain biking. This chapter explores the indivi... Read More about The motivations, identities, and environmental sensibilities of contemporary e-mountain bike users.

The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes (2023)
Journal Article
Aitkenhead, R., Kirkwood, L., Florida-James, G., & Ingram-Sills, L. (2023). The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes. Journal of Applied Sports Sciences, 2, 62-75. https://doi.org/10.37393/JASS.2023.02.6

Female physiology is unique and driven by fluctuations in sex hormones that regulate the menstrual cycle. These hormones present myriad mechanisms that may influence physiological systems, potentially implicating exercise performance. However, resear... Read More about The Influence of Menstruation on Training Schedules in Well-Trained and Elite Female Mountain Bike, Road and Cyclocross Athletes.

Inclusive Design in Innovation: how do we achieve this? (2023)
Presentation / Conference Contribution
Ingram-Sills, L. (2023, August). Inclusive Design in Innovation: how do we achieve this?. Presented at Power of the Bike Summit, Glentress

The future directions and trends for off road e-bike use and impact in Great Britain (2023)
Report
Ingram-Sills, L., Campbell, T., Kirkwood, L., & Florida-James, G. (2023). The future directions and trends for off road e-bike use and impact in Great Britain. British Cycling

The introduction of e-bikes into the cycling industry has resulted in a growing market, with sales demonstrating an increase exponentially over the last five years. Globally it is predicted that e-bikes will reach and potentially surpass 130 million... Read More about The future directions and trends for off road e-bike use and impact in Great Britain.

The Future Directions & Trends for Off Road e-MTB Use & Impact in Great Britian (2022)
Presentation / Conference Contribution
Ingram-Sills, L., Moseley, T., Cook, D., Kirkwood, L., Campbell, T., & Florida-James, G. (2022, November). The Future Directions & Trends for Off Road e-MTB Use & Impact in Great Britian. Presented at The Scottish Mountain Bike Conference, Aberdeen

Influence of menstruation on training schedules in female mountain bike athletes (2022)
Presentation / Conference Contribution
Aitkenhead, R., Kirkwood, L., Florida-James, G., & Ingram-Sills, L. (2022, April). Influence of menstruation on training schedules in female mountain bike athletes. Poster presented at The Biomedical Basis of Elite Performance 2022 (The Physiological Society), Nottingham

Female participation in elite sport is rising, the most recent Olympic games, Tokyo 2020, was the most gender-balanced games in history but research within female athletes is lacking. This study investigated if different phases of the menstrual cycle... Read More about Influence of menstruation on training schedules in female mountain bike athletes.

Seven tips to get your sleep cycle back on track during lockdown (2020)
Newspaper / Magazine
Ingram-Sills, L. (2020). Seven tips to get your sleep cycle back on track during lockdown. https://theconversation.com/seven-tips-to-get-your-sleep-cycle-back-on-track-during-lockdown-135595

Ingram-Sills, L. (2020). Seven tips to get your sleep cycle back on track during lockdown. https://theconversation.com/seven-tips-to-get-your-sleep-cycle-back-on-track-during-lockdown-135595

Competitive mountain bike racing: a study of rider hand-arm vibration exposure (2019)
Presentation / Conference Contribution
Ingram-Sills, L., Taylor, M., Malone, E., Kirkwood, L., & Florida-James, G. (2019, September). Competitive mountain bike racing: a study of rider hand-arm vibration exposure. Presented at 54th UK Conference on Human Responses to Vibration, Edinburgh, Scotland

Limited information is available regarding the hand-arm vibration (HAV) exposure for professional off-road cyclists. Previous research has suggested that commuting and recreational cyclists are at risk of exceeding exposure limit values (ELV) in a si... Read More about Competitive mountain bike racing: a study of rider hand-arm vibration exposure.

Ultra-endurance exercise & the Immune System (2018)
Presentation / Conference Contribution
Ingram-Sills, L. (2018, November). Ultra-endurance exercise & the Immune System. Presented at Developing Mountain Biking In Scotland, Aviemore, Scotland

Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men (2018)
Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018). Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), Article e13697. https://doi.org/10.14814/phy2.13697

Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative ability. CD31+ T-cells (angiogenic T-cells; TANG) possess highly angiogenic capa... Read More about Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men.

The energy expenditure differences between unilateral transtibial and transfemoral amputees during a walking task (2018)
Presentation / Conference Contribution
Gordon, H., & Ingram-Sills, L. (2018, April). The energy expenditure differences between unilateral transtibial and transfemoral amputees during a walking task. Poster presented at BASES student conference, Northumbria University

Physiological characteristics and performance in elite enduro mountain biking (2017)
Journal Article
Kirkwood, L., Ingram, L., Cunningham, J., Malone, E., & Florida-James, G. (2017). Physiological characteristics and performance in elite enduro mountain biking. Journal of Science and Cycling, 6(2), 13-21. https://doi.org/10.28985/171231.jsc.09

Enduro mountain bike racing is composed of several timed predominantly downhill race stages linked by time restricted, non-competitive transition stages. This study aimed to 1) detail and compare the laboratory assessed physiological characteristics... Read More about Physiological characteristics and performance in elite enduro mountain biking.

Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men (2017)
Journal Article
Ross, M. D., Malone, E. M., Simpson, R., Cranston, I., Ingram, L., Wright, G. P., Chambers, G., & Florida-James, G. D. (2018). Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men. American journal of physiology. Heart and circulatory physiology, 314(3), 392-402. https://doi.org/10.1152/ajpheart.00592.2017

Ageing is associated with a dysfunctional endothelial phenotype, as well as reduced angiogenic capabilities. Exercise exerts beneficial effects on the cardiovascular system, possibly by increasing/maintaining the number and/or function of circulating... Read More about Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men.

Acute sleep disruption: does it limit performance but heighten immunity? (2016)
Presentation / Conference Contribution
Ingram-Sills, L., Simpson, R., Malone, E., & Florida-James, G. (2016, July). Acute sleep disruption: does it limit performance but heighten immunity?. Presented at 3rd World Congress of Cycling Science, Caen, France

Introduction: Alterations to sleep patterns in athletes are commonly reported prior to competition and during travel to events (Juliff et al., 2015; Erlacher et al., 2011). When sleep is completely deprived decrements in performance and increased per... Read More about Acute sleep disruption: does it limit performance but heighten immunity?.

A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells (2016)
Journal Article
Ross, M., Tormey, P., Ingram, L., Simpson, R., Malone, E., & Florida-James, G. (2016). A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells. Experimental Physiology, 101(10), 1253-1264. https://doi.org/10.1113/ep085771

New Findings
What is the central question of the study?
Are CD31+ angiogenic T (TANG) cells preferentially mobilized in response to acute exercise?
What is the main finding and its importance?
Our study reveals that TANG cells are redistributed i... Read More about A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells.

Coconut-oil supplementation increases the number of senescent T-lymphocytes in blood at rest: potential implications for an inflammatory environment (2015)
Presentation / Conference Contribution
Brown, F., Dick, J., Bell, G., Witard, O., Alexander, L., Ingram-Sills, L., & Galloway, S. (2015, March). Coconut-oil supplementation increases the number of senescent T-lymphocytes in blood at rest: potential implications for an inflammatory environment. Presented at Metabolic Drivers of Immunity, Aston University, UK

Lymphocyte subset responses to an acute bout of intense exercise following a night of sleep disruption. (2011)
Presentation / Conference Contribution
Ingram-Sills, L., Simpson, R., Malone, E., & Florida-James, G. (2011, July). Lymphocyte subset responses to an acute bout of intense exercise following a night of sleep disruption. Poster presented at 10th International Society of Exercise Immunology Conference, Oxford, UK

Lymphocyte response to a bout of intense exercise following a night’s sleep disruption (2010)
Presentation / Conference Contribution
Ingram-Sills, L. (2010, April). Lymphocyte response to a bout of intense exercise following a night’s sleep disruption. Poster presented at An Integrated Approach to Research in Infectious Diseases, University of Birmingham, UK

Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise (2008)
Journal Article
Simpson, R. J., Cosgrove, C., Ingram, L. A., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2008). Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise. Brain, Behavior, and Immunity, 22(4), 544-551. https://doi.org/10.1016/j.bbi.2007.11.002

Senescent T-lymphocytes are antigen-experienced cells that express the killer-cell lectin-like receptor G1 (KLRG1) and/or CD57; fail to clonally expand following further antigenic stimulation and prevail in the resting blood of older adults compared... Read More about Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise.