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Outputs (2383)

Nitric oxide and gall-bladder motor function (1998)
Journal Article
Luman, W., Ardill, J. E. F., Armstrong, E., Smith, G. D., Brett, L., Lessells, A. M., Haynes, W. G., Gray, G. A., Mickley, E. J., Webb, D. J., & Palmer, K. R. (1998). Nitric oxide and gall-bladder motor function. Alimentary pharmacology & therapeutics, 12(5), 425-432. https://doi.org/10.1046/j.1365-2036.1998.00322.x

Background:The L-arginine: nitric oxide (NO) pathway has been shown to be important in the regulation of intestinal motility and NO may be the mediator for nonadrenergic noncholinergic (NANC) neurotransmission.Aim:To determine the role of the L-argin... Read More about Nitric oxide and gall-bladder motor function.

Encounters with doctors: quantity and quality (1999)
Journal Article
Smith, S. D. M., Nicol, K. M., Devereux, J., & Cornbleet, M. A. (1999). Encounters with doctors: quantity and quality. Palliative Medicine, 13(3), 217-223. https://doi.org/10.1191/026921699668267830

Continuity of care and the large numbers of health care professionals who deliver that care are issues that frequently concern patients and their families. This study examined the number of doctors encountered by 50 patients, during the period of the... Read More about Encounters with doctors: quantity and quality.

Chronic pancreatitis: pathophysiology and patient care (2006)
Journal Article
Smith, G., & Fawcett, T. (2006). Chronic pancreatitis: pathophysiology and patient care. Gastrointestinal Nursing, 4(7), 20-26

Chronic pancreatitis represents a continuous and prolonged inflammatory and fibrosing process in the pancreas resulting in permanent exocrine and often also endocrine dysfunction. Patients present with varying degrees of symptom distress. The usual c... Read More about Chronic pancreatitis: pathophysiology and patient care.

Screening for psychiatric illness in the palliative care inpatient setting: a comparison between the Hospital Anxiety and Depression Scale and the General Health Questionnaire-12 (1999)
Journal Article
Le Fevre, P., Devereux, J., Smith, S., Lawrie, S. M., & Cornbleet, M. (1999). Screening for psychiatric illness in the palliative care inpatient setting: a comparison between the Hospital Anxiety and Depression Scale and the General Health Questionnaire-12. Palliative Medicine, 13(5), 399-407. https://doi.org/10.1191/026921699671260095

The objective of this study was to compare the performance of the Hospital Anxiety and Depression Scale (HADS) with the 12-item General Health Questionnaire (GHQ-12) as a screening instrument for the detection of psychiatric disorders in a palliative... Read More about Screening for psychiatric illness in the palliative care inpatient setting: a comparison between the Hospital Anxiety and Depression Scale and the General Health Questionnaire-12.

Irritable bowel syndrome: quality of life and nursing interventions (2006)
Journal Article
Smith, G. D. (2006). Irritable bowel syndrome: quality of life and nursing interventions. British Journal of Nursing, 15(21), 1152-1156

Irritable bowel syndrome (IBS) is a functional bowel disorder. It is one of the most common gastrointestinal diseases diagnosed in medical practice and can account for up to 50% of referrals to gastroenterology outpatient clinics. IBS remains a poor... Read More about Irritable bowel syndrome: quality of life and nursing interventions.

Perspectives of person-centred care (2013)
Journal Article
Steenbergen, E. E., van der Steen, R., Smith, S., Bright, C., & Kaaijk, M. M. (2013). Perspectives of person-centred care. Nursing Standard, 27(48), 35-41. https://doi.org/10.7748/ns2013.07.27.48.35.e7799

Aim To ascertain and compare the perspectives of students and lecturers at Edinburgh Napier University and Hanze University of Applied Sciences, the Netherlands, regarding person-centred care. Method Data were collected using face-to-face, str... Read More about Perspectives of person-centred care.

Adverse and Benevolent Childhood Experiences in Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD): Implications for Trauma-Focused Therapies (2020)
Journal Article
Karatzias, T., Shevlin, M., Fyvie, C., Grandison, G., Garozi, M., Latham, E., Sinclair, M., Ho, G. W. K., McAnee, G., Ford, J. D., & Hyland, P. (2020). Adverse and Benevolent Childhood Experiences in Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD): Implications for Trauma-Focused Therapies. European Journal of Psychotraumatology, 11(1), Article 1793599. https://doi.org/10.1080/20008198.2020.1793599

Objectives We set out to test, using latent variable modelling, whether adverse and benevolent childhood experiences could be best described as a single continuum or two correlated constructs. We also modelled the relationship between adverse and b... Read More about Adverse and Benevolent Childhood Experiences in Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD): Implications for Trauma-Focused Therapies.

Inclusion in the World Health Organization Model List of Essential Medicines of non-vitamin K anticoagulants for treatment of non-valvular atrial fibrillation: A step towards reducing the burden of cardiovascular morbidity and mortality (2020)
Journal Article
Zaidel, E. J., Leng, X., Moshood Adeoye, A., Hakim, F., Karmacharya, B., Katbeh, A., Neubeck, L., Partridge, S., Perel, P., Huffman, M. D., & Di Cesare, M. (2020). Inclusion in the World Health Organization Model List of Essential Medicines of non-vitamin K anticoagulants for treatment of non-valvular atrial fibrillation: A step towards reducing the burden of cardiovascular morbidity and mortality. Global Heart, 15(1), https://doi.org/10.5334/gh.608

Non-vitamin K antagonist oral anticoagulants (NOACs) represent a paradigm shift in the treatment of non-valvular atrial fibrillation (AF) with major practice guidelines around the world recommending NOACs over vitamin K antagonist oral anticoagulants... Read More about Inclusion in the World Health Organization Model List of Essential Medicines of non-vitamin K anticoagulants for treatment of non-valvular atrial fibrillation: A step towards reducing the burden of cardiovascular morbidity and mortality.

ICD-11 Posttraumatic Stress Disorder (PTSD), Complex PTSD (CPTSD) and Adjustment Disorder (AjD): The importance of stressors and traumatic life events (2020)
Journal Article
Karatzias, T., Shevlin, M., Hyland, P., Fyvie, C., Grandison, G., & Ben-Ezra, M. (2021). ICD-11 Posttraumatic Stress Disorder (PTSD), Complex PTSD (CPTSD) and Adjustment Disorder (AjD): The importance of stressors and traumatic life events. Anxiety, Stress and Coping, 34(2), 191-202. https://doi.org/10.1080/10615806.2020.1803006

Background Although ICD-11 adjustment (AjD), posttraumatic stress (PTSD) and complex posttraumatic stress (CPTSD) are commonly diagnosed disorders following exposure to stressful or traumatic life events, their dimensional structure and co-occurren... Read More about ICD-11 Posttraumatic Stress Disorder (PTSD), Complex PTSD (CPTSD) and Adjustment Disorder (AjD): The importance of stressors and traumatic life events.

The Northumberland Exercise Referral Scheme as a universal community weight management programme: a mixed methods exploration of outcomes, expectations and experiences across a social gradient (2020)
Journal Article
Dodd-Reynolds, C. J., Vallis, D., Kasim, A., Akhter, N., & Hanson, C. (2020). The Northumberland Exercise Referral Scheme as a universal community weight management programme: a mixed methods exploration of outcomes, expectations and experiences across a social gradient. International Journal of Environmental Research and Public Health, 17(15), Article 855929. https://doi.org/10.3390/ijerph17155297

Exercise referral schemes (ERS) are internationally recognised, yet little attention has been paid to discrete referral groups, nor the influence of wider social determinants of health. The primary quantitative element of this mixed methods study use... Read More about The Northumberland Exercise Referral Scheme as a universal community weight management programme: a mixed methods exploration of outcomes, expectations and experiences across a social gradient.

Linkage of national health and social care data: a cross-sectional study of multimorbidity and social care use in people aged over 65 years in Scotland (2020)
Journal Article
Henderson, D. A., Atherton, I., McCowan, C., Mercer, S. W., & Bailey, N. (2021). Linkage of national health and social care data: a cross-sectional study of multimorbidity and social care use in people aged over 65 years in Scotland. Age and ageing, 50(1), 176-182. https://doi.org/10.1093/ageing/afaa134

Background: Little is known about the relationship between multimorbidity and social care use (also known as long-term care). The aim of this study was to assess the relationship between receipt of formal social care services and multimorbidity.... Read More about Linkage of national health and social care data: a cross-sectional study of multimorbidity and social care use in people aged over 65 years in Scotland.

Respecting the autonomy of the living and dying (2020)
Journal Article
Stavert, J. (2020). Respecting the autonomy of the living and dying. Journal of Integrated Care, 28(4), 379-385. https://doi.org/10.1108/JICA-06-2020-0038

Purpose To inform those who are supporting persons who are dying and are responsible for planning, commissioning or delivering palliative care about the need to support and maximise the decision-making ability and choices of persons with advanced de... Read More about Respecting the autonomy of the living and dying.

Trauma, PTSD, and Complex PTSD in the Republic of Ireland: Prevalence, service use, comorbidity, and risk factors (2020)
Journal Article
Hyland, P., Vallières, F., Cloitre, M., Ben-Ezra, M., Karatzias, T., Olff, M., Murphy, J., & Shevlin, M. (2021). Trauma, PTSD, and Complex PTSD in the Republic of Ireland: Prevalence, service use, comorbidity, and risk factors. Social Psychiatry and Psychiatric Epidemiology, 56, Article 649-658 (2021). https://doi.org/10.1007/s00127-020-01912-x

Purpose: This study represents the first assessment of the prevalence of trauma exposure, and Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD), ever conducted in the general population of the Republic of Ireland. Additionally, prevalence... Read More about Trauma, PTSD, and Complex PTSD in the Republic of Ireland: Prevalence, service use, comorbidity, and risk factors.

Comparison of Two Ventilator Associated Pneumonia Surveillance Techniques
Presentation / Conference Contribution
Craven, T. H., Wojcik, G., Kefala, K., McCoubrey, J., Reilly, J., Paterson, R., Inverarity, D., Laurenson, I., & Walsh, T. S. (2016, March). Comparison of Two Ventilator Associated Pneumonia Surveillance Techniques. Poster presented at 36th International Symposium on Intensive Care and Emergency Medicine

Predicting Out-of-Office Blood Pressure in the Clinic (PROOF-BP)Novelty and Significance: Derivation and Validation of a Tool to Improve the Accuracy of Blood Pressure Measurement in Clinical Practice (2016)
Journal Article
Sheppard, J. P., Stevens, R., Gill, P., Martin, U., Godwin, M., Hanley, J., Heneghan, C., Hobbs, F. R., Mant, J., McKinstry, B., Myers, M., Nunan, D., Ward, A., Williams, B., & McManus, R. J. (2016). Predicting Out-of-Office Blood Pressure in the Clinic (PROOF-BP)Novelty and Significance: Derivation and Validation of a Tool to Improve the Accuracy of Blood Pressure Measurement in Clinical Practice. Hypertension, 67(5), 941-950. https://doi.org/10.1161/hypertensionaha.115.07108

Patients often have lower (white coat effect) or higher (masked effect) ambulatory/home blood pressure readings compared with clinic measurements, resulting in misdiagnosis of hypertension. The present study assessed whether blood pressure and patien... Read More about Predicting Out-of-Office Blood Pressure in the Clinic (PROOF-BP)Novelty and Significance: Derivation and Validation of a Tool to Improve the Accuracy of Blood Pressure Measurement in Clinical Practice.

Discontinuous change in organizations. Using training and development interventions to develop creativity (1995)
Journal Article
Garavan, T. N., & Deegan, J. (1995). Discontinuous change in organizations. Using training and development interventions to develop creativity. Industrial and Commercial Training, 27(11), 18-25. doi:10.1108/00197859510147607

Considers the availability of objective criteria for creativity enhancement from relevant applied research. Uses research to address the problem of creativity within the framework of artificial intelligence. Compares thinking to using a map and disc... Read More about Discontinuous change in organizations. Using training and development interventions to develop creativity.

A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis (2007)
Journal Article
Stevens, C., Lin, Y., Sanchez, M., Amin, E., Copson, E., White, H., Durston, V., Eccles, D. M., & Hupp, T. (2007). A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis. Journal of Biological Chemistry, 282(18), 13791-13803. https://doi.org/10.1074/jbc.m605649200

p53 is activated genetically by a set of kinases that are components of the calcium calmodulin kinase superfamily, including CHK2, AMP kinase, and DAPK-1. In dissecting the mechanism of DAPK-1 control, a novel mutation (N1347S) was identified in the... Read More about A Germ Line Mutation in the Death Domain of DAPK-1 Inactivates ERK-induced Apoptosis.

Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. (2007)
Journal Article
Lin, Y., Stevens, C., & Hupp, T. (2007). Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. Journal of Biological Chemistry, 282(23), 16792-16802. https://doi.org/10.1074/jbc.M611559200

DAPK-1 is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. To define mechanisms of DAPK-1 protein regulation, we have determined that DAPK-1 protein has a long half-life... Read More about Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis..

DAPK-1 Bbnding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing (2008)
Journal Article
Harrison, B., Kraus, M., Burch, L., Stevens, C., Craig, A., Gordon-Weeks, P., & Hupp, T. R. (2008). DAPK-1 Bbnding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. Journal of Biological Chemistry, 283(15), 9999-10014. https://doi.org/10.1074/jbc.M706040200

DAPK-1 (death-activated protein kinase) has wide ranging functions in cell growth control; however, DAPK-1 interacting proteins that mediate these effects are not well defined. Protein-protein interactions are driven in part by linear interaction mot... Read More about DAPK-1 Bbnding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.