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Outputs (2382)

Regulation of capsule expression (2010)
Book Chapter
Taylor, C., & Roberts, I. S. (2010). Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences, (115-138). Cambridge: Cambridge University Press

No abstract available.

Home-based end of life care for children and their families – a systematic scoping review and narrative synthesis (2020)
Journal Article
Malcolm, C., Katherine, K., & Charlotte, T. (2020). Home-based end of life care for children and their families – a systematic scoping review and narrative synthesis. Journal of Pediatric Nursing, 55, 126-133. https://doi.org/10.1016/j.pedn.2020.07.018

Abstract Problem: There is a growing international drive to deliver children’s palliative care services closer to home. Families should have choice of where end of life (EOL) care is provided with home as one option. This review aims to establish t... Read More about Home-based end of life care for children and their families – a systematic scoping review and narrative synthesis.

Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting (2006)
Journal Article
Vizard, C. G., Rimmer, D. L., Pless-Mulloli, T., Singleton, I., & Air, V. S. (2006). Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting. Science of the Total Environment, 370(1), 61-69. https://doi.org/10.1016/j.scitotenv.2006.06.006

A study of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) concentrations was undertaken in the vicinity of a municipal solid waste incinerator (MSWI) in Newcastle upon Tyne as a result of concerns raised by local re... Read More about Identifying contemporary and historic sources of soil polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in an industrial urban setting.

"We are 'free range' prison officers", the experiences of Scottish Prison Service (SPS) Throughcare Support Officers (TSOs) working in custody and the community (2020)
Journal Article
Maycock, M., McGuckin, K., & Morrison, K. (2020). "We are 'free range' prison officers", the experiences of Scottish Prison Service (SPS) Throughcare Support Officers (TSOs) working in custody and the community. Probation Journal, 67(4), 358-374. https://doi.org/10.1177/0264550520954898

Between 2015 and 2019, forty-one Throughcare Support Officers (TSOs) supported people serving short sentences leaving custody across eleven Scottish Prison Service (SPS) establishments. The role of prison officers in the provision of throughcare in t... Read More about "We are 'free range' prison officers", the experiences of Scottish Prison Service (SPS) Throughcare Support Officers (TSOs) working in custody and the community.

Potential use of DNA adducts to detect mutagenic compounds in soil (2008)
Journal Article
Hua, G., Lyons, B., Killham, K., & Singleton, I. (2009). Potential use of DNA adducts to detect mutagenic compounds in soil. Environmental Pollution, 157(3), 916-921. https://doi.org/10.1016/j.envpol.2008.10.026

In this study, three different soils with contrasting features, spiked with 300 mg benzo[a]pyrene (BaP)/kg dry soil, were incubated at 20 °C and 60% water holding capacity for 540 days. At different time points, BaP and {DNA} were extracted and quant... Read More about Potential use of DNA adducts to detect mutagenic compounds in soil.

A pilot study comparing a type 1 nurse-led diabetes clinic with a conventional doctor-led diabetes clinic (2004)
Journal Article
Charlton, J., Mackay, L., & McKnight, J. (2004). A pilot study comparing a type 1 nurse-led diabetes clinic with a conventional doctor-led diabetes clinic. European Diabetes Nursing, 1(1), 18-21. https://doi.org/10.1002/edn.4

A prospective comparative pilot study was designed to assess and compare care delivered by a diabetes specialist nurse (DSN) and standard doctor-led care for patients with type 1 diabetes. The philosophy was to provide an individualised, patient-cent... Read More about A pilot study comparing a type 1 nurse-led diabetes clinic with a conventional doctor-led diabetes clinic.

Bacterial Capsules: A Route for Polysaccharide Engineering (2005)
Book Chapter
Roberts, I., & Taylor, C. (2005). Bacterial Capsules: A Route for Polysaccharide Engineering. In Handbook of Carbohydrate Engineering, 479-494. Boca Raton, USA: CRC Press (Taylor and Francis Group). doi:10.1201/9781420027631.ch16

No abstract available.

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis (2009)
Journal Article
Wright, G. P., Notley, C. A., Xue, S. A., Bendle, G. M., Holler, A., Schumacher, T. N., Ehrenstein, M. R., & Stauss, H. J. (2009). Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis. Proceedings of the National Academy of Sciences, 106(45), 19078-19083. https://doi.org/10.1073/pnas.0907396106

Regulatory T cells (Tregs) can suppress a wide range of immune cells, making them an ideal candidate for the treatment of autoimmunity. The potential clinical translation of targeted therapy with antigen-specific Tregs is hampered by the difficulties... Read More about Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis.

CD3 limits the efficacy of TCR gene therapy in vivo (2011)
Journal Article
Ahmadi, M., King, J. W., Xue, S. A., Voisine, C., Holler, A., Wright, G. P., …Stauss, H. J. (2011). CD3 limits the efficacy of TCR gene therapy in vivo. Blood, 118(13), 3528-3537. https://doi.org/10.1182/blood-2011-04-346338

The function of T-cell receptor (TCR) gene modified T cells is dependent on efficient surface expression of the introduced TCR / heterodimer. We tested whether endogenous CD3 chains are rate-limiting for TCR expression and antigen-specific T-cell fu... Read More about CD3 limits the efficacy of TCR gene therapy in vivo.

Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells (2011)
Journal Article
Notley, C. A., Brown, M. A., Wright, G. P., & Ehrenstein, M. R. (2011). Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells. The journal of immunology : official journal of the American Association of Immunologists, 186(8), 4967-4972. https://doi.org/10.4049/jimmunol.1003021

The clearance of dying cells is vital for re-establishing tolerance during inflammation and has potent immunoregulatory consequences. Because natural IgM plays a key role in the removal of apoptotic cells, we investigated whether the immune modulator... Read More about Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells.

Nurses' health-related behaviours: protocol for a quantitative systematic review of prevalence of tobacco smoking, physical activity, alcohol consumption and dietary habits (2015)
Journal Article
Neall, R. A., Atherton, I. M., & Kyle, R. G. (2016). Nurses' health-related behaviours: protocol for a quantitative systematic review of prevalence of tobacco smoking, physical activity, alcohol consumption and dietary habits. Journal of Advanced Nursing, 72(1), 197-204. https://doi.org/10.1111/jan.12739

Aim To enumerate nurses' health-related behaviour by critically appraising studies on tobacco smoking, physical activity, alcohol consumption and dietary habits. Background Nurses represent the largest occupational group in healthcare systems in... Read More about Nurses' health-related behaviours: protocol for a quantitative systematic review of prevalence of tobacco smoking, physical activity, alcohol consumption and dietary habits.

Does requiring trauma exposure affect rates of ICD-11 PTSD and complex PTSD? Implications for DSM-5 (2020)
Journal Article
Hyland, P., Karatzias, T., Shevlin, M., Mcelroy, E., Ben-Ezra, M., Cloitre, M., & Brewin, C. R. (2021). Does requiring trauma exposure affect rates of ICD-11 PTSD and complex PTSD? Implications for DSM-5. Psychological Trauma: Theory, Research, Practice, and Policy, 13(2), 133-141. https://doi.org/10.1037/tra0000908

Objective: There is little evidence that posttraumatic stress disorder (PTSD) is more likely to follow traumatic events defined by Criterion A than non-Criterion A stressors. Criterion A events might have greater predictive validity for ICD-11 PTSD w... Read More about Does requiring trauma exposure affect rates of ICD-11 PTSD and complex PTSD? Implications for DSM-5.

Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice (2006)
Journal Article
Brown, M., & Marshall, K. (2006). Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice. Journal of Psychiatric and Mental Health Nursing, 13(2), 234-241. https://doi.org/10.1111/j.1365-2850.2006.00947.x

People with learning disabilities are an ageing and increasing population and have been the subject of policy initiatives by the four countries of the UK, detailing the range of supports that need to be in place for this group. The evidence base of t... Read More about Cognitive behaviour therapy and people with learning disabilities: implications for developing nursing practice.

Managing blood glucose during and after exercise in Type 1 diabetes: reproducibility of glucose response and a trial of a structured algorithm adjusting insulin and carbohydrate intake: Managing blood glucose during exercise (2011)
Journal Article
Kilbride, L., Charlton, J., Aitken, G., Hill, G. W., Davison, R. C., & McKnight, J. A. (2011). Managing blood glucose during and after exercise in Type 1 diabetes: reproducibility of glucose response and a trial of a structured algorithm adjusting insulin and carbohydrate intake: Managing blood glucose during exercise. Journal of Clinical Nursing, 20(23-24), 3423-3429. https://doi.org/10.1111/j.1365-2702.2011.03771.x

AIMS AND OBJECTIVES: To enable people with Type 1 diabetes to exercise safely by investigating the reproducibility of the glucose response to an algorithm for carbohydrate and insulin adjustment during and after exercise compared to their self-manag... Read More about Managing blood glucose during and after exercise in Type 1 diabetes: reproducibility of glucose response and a trial of a structured algorithm adjusting insulin and carbohydrate intake: Managing blood glucose during exercise.

Type 1, tents, take-aways and toilets: how to manage at a music festival (2010)
Journal Article
Charlton, J., & Mackay, L. (2010). Type 1, tents, take-aways and toilets: how to manage at a music festival. Practical Diabetes International, 27(7), 272-275. https://doi.org/10.1002/pdi.1501

Maintaining optimal glycaemic control in people with type 1 diabetes is challenging. Attending a weekend music festival encompasses lifestyle activities that increase the challenge. These include: increased exercise, and changes in eating and alcohol... Read More about Type 1, tents, take-aways and toilets: how to manage at a music festival.

A digital health intervention for cardiovascular disease management in primary care (CONNECT) randomized controlled trial (2020)
Journal Article
Redfern, J., Coorey, G., Mulley, J., Scaria, A., Neubeck, L., Hafiz, N., Pitt, C., Weir, K., Forbes, J., Parker, S., Bampi, F., Coenen, A., Enright, G., Wong, A., Nguyen, T., Harris, M., Zwar, N., Chow, C., Rodgers, A., Heeley, E., …Peiris, D. (2020). A digital health intervention for cardiovascular disease management in primary care (CONNECT) randomized controlled trial. npj Digital Medicine, 3, Article 117 (2020). https://doi.org/10.1038/s41746-020-00325-z

Digital health applications (apps) have the potential to improve health behaviors and outcomes. We aimed to examine the effectiveness of a consumer web-based app linked to primary care electronic health records (EHRs). CONNECT was a multicenter rando... Read More about A digital health intervention for cardiovascular disease management in primary care (CONNECT) randomized controlled trial.

Family and Mobility in Second Modernity: Polish Migrant Narratives of Individualization and Family Life (2013)
Journal Article
Botterill, K. (2014). Family and Mobility in Second Modernity: Polish Migrant Narratives of Individualization and Family Life. Sociology, 48(2), 233-250. https://doi.org/10.1177/0038038512474728

This article revisits the individualization debate in the context of Polish migration to the UK. Drawing on empirical research with young Polish migrants in Scotland and Poland, I argue that as new opportunities for migration have shaped Polish famil... Read More about Family and Mobility in Second Modernity: Polish Migrant Narratives of Individualization and Family Life.

The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies (1989)
Book Chapter
Darlison, M. G., Barnard, E. A., Bateson, A. N., Glencorse, T. A., Harvey, R. J., Hicks, A. A., Hunt, S. P., Morris, B. J., Vallejo, M., Vreugdenhil, E., & Wisden, W. (1989). The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies. In Molecular Biology of Neuroreceptors and Ion Channels (83-99). Springer. https://doi.org/10.1007/978-3-642-74155-5_7

It is well established that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) mediates many of its effects by binding to the GABAA receptor, which is present on the majority of mammalian brain neurons (Enna, 1983), resulting in the opening o... Read More about The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies.