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Outputs (90)

Association between allopurinol use and hip fracture in older patients (2016)
Journal Article
Basu, U., Goodbrand, J., McMurdo, M. E., Donnan, P. T., McGilchrist, M., Frost, H., George, J., & Witham, M. D. (2016). Association between allopurinol use and hip fracture in older patients. Bone, 84, 189-193. https://doi.org/10.1016/j.bone.2016.01.003

Background Allopurinol reduces oxidative stress and interacts with purinergic signalling systems important in bone metabolism and muscle function. We assessed whether allopurinol use was associated with a reduced incidence of hip fracture in older p... Read More about Association between allopurinol use and hip fracture in older patients.

Is referral of postsurgical colorectal cancer survivors to cardiac rehabilitation feasible and acceptable? A pragmatic pilot randomised controlled trial with embedded qualitative study (2016)
Journal Article
Hubbard, G., Adams, R., Campbell, A., Kidd, L., Leslie, S. J., Munro, J., & Watson, A. (2016). Is referral of postsurgical colorectal cancer survivors to cardiac rehabilitation feasible and acceptable? A pragmatic pilot randomised controlled trial with embedded qualitative study. BMJ Open, 6(1), Article e009284. https://doi.org/10.1136/bmjopen-2015-009284

Objectives (1) Assess whether cardiac rehabilitation (CR) is a feasible and acceptable model of rehabilitation for postsurgical colorectal cancer (CRC) survivors, (2) evaluate trial procedures. This article reports the results of the first objective.... Read More about Is referral of postsurgical colorectal cancer survivors to cardiac rehabilitation feasible and acceptable? A pragmatic pilot randomised controlled trial with embedded qualitative study.

"Horses for Courses" Comment on "Translating Evidence Into Healthcare Policy and Practice: Single Versus Multi-Faceted Implementation Strategies – Is There a Simple Answer to a Complex Question?" (2015)
Journal Article
Wilkinson, J. E., & Frost, H. (2015). "Horses for Courses" Comment on "Translating Evidence Into Healthcare Policy and Practice: Single Versus Multi-Faceted Implementation Strategies – Is There a Simple Answer to a Complex Question?". International Journal of Health Policy and Management, 4(10), 685-686

This commentary considers the vexed question of whether or not we should be spending time and resources on using multifaceted interventions to undertake implementation of evidence in healthcare. A review of systematic reviews has suggested that simpl... Read More about "Horses for Courses" Comment on "Translating Evidence Into Healthcare Policy and Practice: Single Versus Multi-Faceted Implementation Strategies – Is There a Simple Answer to a Complex Question?".

Association Between Kidney Function, Rehabilitation Outcome, and Survival in Older Patients Discharged From Inpatient Rehabilitation (2015)
Journal Article
Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E., Donnan, P. T., McGilchrist, M. M., Frost, H., & Witham, M. D. (2015). Association Between Kidney Function, Rehabilitation Outcome, and Survival in Older Patients Discharged From Inpatient Rehabilitation. American Journal of Kidney Diseases, 66(5), 768-774. https://doi.org/10.1053/j.ajkd.2015.04.041

Background
Chronic kidney disease (CKD) is common in older people, but it is unclear if it affects survival and rehabilitation outcomes independent of comorbid conditions and physical function in this population.

Study Design
Cohort analysis of... Read More about Association Between Kidney Function, Rehabilitation Outcome, and Survival in Older Patients Discharged From Inpatient Rehabilitation.

The Relationship Between Renal Function, Physical Function and Survival In Older Patients Discharged From Inpatient Rehabilitation (2015)
Journal Article
Doyle, E. M., Sloan, J. M., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., & Witham, M. D. (2015). The Relationship Between Renal Function, Physical Function and Survival In Older Patients Discharged From Inpatient Rehabilitation. Age and ageing, 44(suppl 1), i11-i11. https://doi.org/10.1093/ageing/afv031.01

No abstract available.

Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship (2015)
Journal Article
Christensen, J. F., Bandak, M., Campbell, A., Jones, L. W., & Højman, P. (2015). Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta oncologica, 54(5), 592-599. https://doi.org/10.3109/0284186x.2014.995776

Treatment of testicular germ cell cancer constitutes a major success story in modern oncology. Today, the vast majority of patients are cured by a therapeutic strategy using one or more highly effective components including surgery (orchiectomy), rad... Read More about Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship.

Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review (2014)
Journal Article
Graham, S. M., Baird, M., & Boyd, G. W. (2014). Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease, 4(3), 286-298. https://doi.org/10.5628/aehd.v4i3.169

Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic neurons in
the substantia nigra region of the brain. Symptoms and signs m... Read More about Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review.

Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up (2014)
Journal Article
Trinh, L., Mutrie, N., Campbell, A. M., Crawford, J. J., & Courneya, K. S. (2014). Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up. European Journal of Oncology Nursing, 18(6), 557-563. https://doi.org/10.1016/j.ejon.2014.07.004

Short-term physical activity (PA) has beneficial effects on symptom management and quality of life, however, longer-term adherence is likely needed for improved disease outcomes in breast cancer survivors (BCS). This study examined the effects of a s... Read More about Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up.

Construction of a linked health and social care database resource – lessons on process, content and culture (2014)
Journal Article
Witham, M. D., Frost, H., McMurdo, M., Donnan, P. T., & McGilchrist, M. (2015). Construction of a linked health and social care database resource – lessons on process, content and culture. Informatics for Health and Social Care, 40(3), 229-239. https://doi.org/10.3109/17538157.2014.892491

Background: Combining routinely collected health and social care data on older people is essential to advance both service delivery and research for this client group. Little data is available on how to combine health and social care data; this artic... Read More about Construction of a linked health and social care database resource – lessons on process, content and culture.

Interventions in community settings that prevent or delay disablement in later life: an overview of the evidence (2012)
Journal Article
Frost, H., Haw, S., & Frank, J. (2012). Interventions in community settings that prevent or delay disablement in later life: an overview of the evidence. Quality in Ageing and Older Adults, 13(3), 212-230. https://doi.org/10.1108/14717791211264241

Purpose - The population of older people in the UK is expected to rise rapidly over the next 20 years and therefore identification of effective interventions that prevent functional decline and disablement is a public health priority. This review sum... Read More about Interventions in community settings that prevent or delay disablement in later life: an overview of the evidence.

Experiences of knowledge brokering for evidence-informed public health policy and practice: three years of the Scottish Collaboration for Public Health Research and Policy (2012)
Journal Article
Frost, H., Geddes, R., Haw, S., Jackson, C. A., Jepson, R., Mooney, J. D., & Frank, J. (2012). Experiences of knowledge brokering for evidence-informed public health policy and practice: three years of the Scottish Collaboration for Public Health Research and Policy. Evidence and Policy, 8(3), 347-359. https://doi.org/10.1332/174426412x654068

Despite a burgeoning literature on, and widespread interest in, knowledge translation and exchange in public health, few articles provide an account of the actual experiences of knowledge brokerage organisations. The Scottish Collaboration for Public... Read More about Experiences of knowledge brokering for evidence-informed public health policy and practice: three years of the Scottish Collaboration for Public Health Research and Policy.

Public health programme and policy options for improving health equitably (2011)
Journal Article
Haw, S., Frank, J., Frost, H., Geddes, R., Jackson, C., & Mooney, J. (2011). Public health programme and policy options for improving health equitably. Journal of the Royal College of Physicians of Edinburgh, 41(1), 3-4. https://doi.org/10.4997/jrcpe.2011.101

First paragraph: Compared with other Western European countries, Scotland has the highest mortality rate and lowest life expectancy. Scotland is also characterised by marked inequalities, with men from the poorest communities dying 13 years earlier a... Read More about Public health programme and policy options for improving health equitably.

The MRC Spine Stabilization Trial: Surgical Methods, Outcomes, Costs, and Complications of Surgical Stabilization (2008)
Journal Article
Wilson-MacDonald, J., Fairbank, J., Frost, H., Yu, L.-M., Barker, K., Collins, R., & Campbell, H. (2008). The MRC Spine Stabilization Trial: Surgical Methods, Outcomes, Costs, and Complications of Surgical Stabilization. Spine, 33(21), 2334-2340. https://doi.org/10.1097/brs.0b013e318186a8b2

STUDY DESIGN:
A review of the surgical costs and results in a group of patients randomly allocated to surgery as part of a large prospective randomized trial of patients with chronic back pain.
OBJECTIVE:
To report the observational data from the... Read More about The MRC Spine Stabilization Trial: Surgical Methods, Outcomes, Costs, and Complications of Surgical Stabilization.

Responsiveness of a Patient Specific Outcome Measure Compared With the Oswestry Disability Index v2.1 and Roland and Morris Disability Questionnaire for Patients With Subacute and Chronic Low Back Pain (2008)
Journal Article
Frost, H., Lamb, S. E., & Stewart-Brown, S. (2008). Responsiveness of a Patient Specific Outcome Measure Compared With the Oswestry Disability Index v2.1 and Roland and Morris Disability Questionnaire for Patients With Subacute and Chronic Low Back Pain. Spine, 33(22), 2450-2457. https://doi.org/10.1097/brs.0b013e31818916fd

STUDY DESIGN:
A prospective cohort.
OBJECTIVE:
The aim of this study was to compare the responsiveness of a patient specific outcome measure with the Oswestry Disability Index v2.1 (ODI) and the Roland and Morris Disability Questionnaire (RMDQ) fo... Read More about Responsiveness of a Patient Specific Outcome Measure Compared With the Oswestry Disability Index v2.1 and Roland and Morris Disability Questionnaire for Patients With Subacute and Chronic Low Back Pain.

Quality of life among survivors of prolonged critical illness; a mixed methods study (2008)
Journal Article
Ramsay, P., Huby, G., Thompson, A., & Walsh, T. (2008). Quality of life among survivors of prolonged critical illness; a mixed methods study. Critical care : the official journal of the Critical Care Forum, 12(Suppl 2), P508. https://doi.org/10.1186/cc6729

Introduction:
Survivors of prolonged critical illness (requiring ≥ 14 days ventilation) experience the highest prevalence and severest forms of critical illness-related morbidity. This study examines the degree to which generic questionnaires reflec... Read More about Quality of life among survivors of prolonged critical illness; a mixed methods study.

An assessment of the validity of spectral entropy as a measure of sedation statein mechanically ventilated critically ill patients (2007)
Journal Article
Walsh, T. S., Ramsay, P., Lapinlampi, T. P., Särkelä, M. O. K., Viertiö-Oja, H. E., & Meriläinen, P. T. (2008). An assessment of the validity of spectral entropy as a measure of sedation statein mechanically ventilated critically ill patients. Intensive Care Medicine, 34(2), 308-315. https://doi.org/10.1007/s00134-007-0858-x

To assess whether the Entropy Module (GE Healthcare, Helsinki, Finland), a device to measure hypnosis in anesthesia, is a valid measure of sedation state in critically ill patients by comparing clinically assessed sedation state with Spectral Entropy... Read More about An assessment of the validity of spectral entropy as a measure of sedation statein mechanically ventilated critically ill patients.

Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial (2007)
Journal Article
Mutrie, N., Campbell, A. M., Whyte, F., McConnachie, A., Emslie, C., Lee, L., Kearney, N., Walker, A., & Ritchie, D. (2007). Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial. BMJ, 334(7592), 517. https://doi.org/10.1136/bmj.39094.648553.ae

Objectives To determine functional and psychological benefits of a 12 week supervised group exercise programme during treatment for early stage breast cancer, with six month follow-up.Design Pragmatic randomised controlled prospective open trial.Sett... Read More about Benefits of supervised group exercise programme for women being treated for early stage breast cancer: pragmatic randomised controlled trial.

Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT (2007)
Journal Article
Ziebland, S., Featherstone, K., Snowdon, C., Barker, K., Frost, H., & Fairbank, J. (2007). Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT. Trials, 8(1), 1-7. https://doi.org/10.1186/1745-6215-8-4

Background Qualitative methods are increasingly used to study the process of clinical trials and patients understanding of the rationale for trials, randomisation and reasons for taking part or refusing. Patients' understandings are inevitably influ... Read More about Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT.

Cost-Utility Analysis of Physiotherapy Treatment Compared With Physiotherapy Advice in Low Back Pain (2006)
Journal Article
Rivero-Arias, O., Gray, A., Frost, H., Lamb, S. E., & Stewart-Brown, S. (2006). Cost-Utility Analysis of Physiotherapy Treatment Compared With Physiotherapy Advice in Low Back Pain. Spine, 31(12), 1381-1387. https://doi.org/10.1097/01.brs.0000218486.13659.d5

STUDY DESIGN:
Economic evaluation alongside a pragmatic multicenter randomized controlled trial from the National Health Service (NHS) and societal perspective.
OBJECTIVE:
To perform a cost-utility analysis of routine physiotherapy treatment compa... Read More about Cost-Utility Analysis of Physiotherapy Treatment Compared With Physiotherapy Advice in Low Back Pain.