Dr Giacomo Russo's Projects (3)

Development of new sustainable approach in drug discovery: One-pot parallel synthetic strategy to minimise the environmental footprint May 1, 2024 - Apr 30, 2025
Over thousands of Medicinal Chemistry research groups around the world across academia, research-based institutions are involved in synthesizing libraries of compounds in the early drug discovery phase. During this synthetic process, massive amount o... Read More about Development of new sustainable approach in drug discovery: One-pot parallel synthetic strategy to minimise the environmental footprint.

Development of an immobilized artificial membrane liquid chromatography /mass spectrometry-based platform to assess the pulmonary permeability of drug candidates. Jun 12, 2023 - Aug 4, 2023
In this project, 53 analytes whose apparent permeability through Calu-3 cell line is known from the literature (Lin, Chiu, Wang, & Tung, 2022) will be studied by immobilized artificial membrane (IAM)- HPLC. Indeed, Berry and co-workers (Zemski Berry... Read More about Development of an immobilized artificial membrane liquid chromatography /mass spectrometry-based platform to assess the pulmonary permeability of drug candidates..

Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease. Feb 14, 2022 - Nov 13, 2023
Lactoferrin (LF) is a glycoprotein which is widely contained in many secretory fluids, mainly milk but also saliva, tears, and nasal secretions. Many scientific reports supported an application of this glycoprotein in the prophylaxis and treatment of... Read More about Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease..