Skip to main content

Research Repository

Advanced Search

Development of new sustainable approach in drug discovery: One-pot parallel synthetic strategy to minimise the environmental footprint

People Involved

Project Description

Over thousands of Medicinal Chemistry research groups around the world across academia, research-based institutions are involved in synthesizing libraries of compounds in the early drug discovery phase. During this synthetic process, massive amount of chemicals, reagents, solvents, and power consumption are observed that have a significant negative impact on the sustainability. New directions and strategies must be incorporated into the drug discovery process to minimize the consumption these environmental factors to improve the environmental footprint. We aim to improve the sustainable laboratory practice through designing a new one-pot parallel synthetic approach where several target compounds will be synthesized in a single reaction cell to minimize the consumptions of these environmental factors.

Type of Project P04 - Research Charities and Trusts
Status Project Live
Funder(s) Royal Society of Chemistry
Value £9,240.00
Project Dates May 1, 2024 - Apr 30, 2025



You might also like

Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease. Feb 14, 2022 - Nov 13, 2023
Lactoferrin (LF) is a glycoprotein which is widely contained in many secretory fluids, mainly milk but also saliva, tears, and nasal secretions. Many scientific reports supported an application of this glycoprotein in the prophylaxis and treatment of... Read More about Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease..

Development of an immobilized artificial membrane liquid chromatography /mass spectrometry-based platform to assess the pulmonary permeability of drug candidates. Jun 12, 2023 - Aug 4, 2023
In this project, 53 analytes whose apparent permeability through Calu-3 cell line is known from the literature (Lin, Chiu, Wang, & Tung, 2022) will be studied by immobilized artificial membrane (IAM)- HPLC. Indeed, Berry and co-workers (Zemski Berry... Read More about Development of an immobilized artificial membrane liquid chromatography /mass spectrometry-based platform to assess the pulmonary permeability of drug candidates..

British Council - TNE Exploratory Grant - with ACU Jan 1, 2025 - Dec 31, 2025
Co-development of a Professional Diploma in Pharmaceutical Science - a first step to a long-term educational partnership between Edinburgh Napier University (UK) and Ahram Canadian University (Egypt)