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All Outputs (567)

Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. (2005)
Journal Article
Dias, N., Goossens, J., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., Bernal, J., Turnbull, A., Mincher, D., & Bailly, C. (2005). Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. Bioconjugate Chemistry, 16(4), 949-958. https://doi.org/10.1021/bc050065x

We report the synthesis of an original series of oxoazabenzo[de]anthracenes conjugated to an amino acid: Ala, Phe, Pro, Lys, or Gly (4a-e, respectively). The compounds, derived from 1,8-dihydroxyanthracene-9,10-dione, were studied for DNA binding and... Read More about Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents..

Implementing Road User Charging: The Lessons Learnt from Hong Kong, Cambridge and Central London (2005)
Journal Article
Ison, S. G., & Rye, T. (2005). Implementing Road User Charging: The Lessons Learnt from Hong Kong, Cambridge and Central London. Transport Reviews, 25(4), 451-465. https://doi.org/10.1080/0144164042000335788

Road user charging has long been advocated as a means of dealing with congestion in urban areas. Numerous schemes have been proposed but have advanced little beyond the drawing board. This paper draws on the experiences of two such road user charging... Read More about Implementing Road User Charging: The Lessons Learnt from Hong Kong, Cambridge and Central London.

Modelling of flow rate in a photovoltaic-driven roof slate-based solar ventilation air preheating system (2005)
Journal Article
Odeh, N., Grassie, T., Henderson, D., & Muneer, T. (2006). Modelling of flow rate in a photovoltaic-driven roof slate-based solar ventilation air preheating system. Energy Conversion and Management, 47(7-8), 909-925. https://doi.org/10.1016/j.enconman.2005.06.005

This paper describes the modelling of flow rate in a photovoltaic (PV) driven, roof slate based solar system for preheating ventilation air in cold climates. The system consists of a photovoltaic driven, attic mounted fan, which draws air through the... Read More about Modelling of flow rate in a photovoltaic-driven roof slate-based solar ventilation air preheating system.

Steroid signalling in the ovarian surface epithelium (2005)
Journal Article
Rae, M. T., & Hillier, S. G. (2005). Steroid signalling in the ovarian surface epithelium. Trends in Endocrinology and Metabolism, 16(7), 327-333. https://doi.org/10.1016/j.tem.2005.07.002

Human ovarian surface epithelium (HOSE) undergoes serial injury-repair with each ovulation, which is probably why most ovarian epithelial cancers arise there. Considering the proposed inflammatory aetiology of ovarian cancer, anti-inflammatory steroi... Read More about Steroid signalling in the ovarian surface epithelium.

The experience of older workers. (2005)
Presentation / Conference Contribution
Raeside, R., Gayen, K., & McQuaid, R. W. (2005). The experience of older workers.

Partitioning and Bioavailability (2005)
Book Chapter
Philp, J., Stainsby, F., & Dunbar, S. (2005). Partitioning and Bioavailability. In Water encyclopediaWiley. doi:10.1002/047147844x.pc441

As soon as a chemical is spilled it becomes a pollutant, but the fate of that pollutant depends to a large degree on its chemistry, which determines how it will partition to various “compartments,” or phases, of the environment. This idea is enshrine... Read More about Partitioning and Bioavailability.

Animated interval scatter-plot views for the exploratory analysis of large scale microarray time-course data. (2005)
Journal Article
Craig, P., Kennedy, J., & Cumming, A. (2005). Animated interval scatter-plot views for the exploratory analysis of large scale microarray time-course data. Information Visualization, 4(3), 149-163. https://doi.org/10.1057/palgrave.ivs.9500101

Microarray technologies are a relatively new development that allow biologists to monitor the activity of thousands of genes (normally around 8,000) in parallel across multiple stages of a biological process. While this new perspective on biological... Read More about Animated interval scatter-plot views for the exploratory analysis of large scale microarray time-course data..

Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model (2005)
Journal Article
Van Valckenborgh, E., Mincher, D., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., & Vanderkerken, K. (2005). Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model. Leukemia, 19(9), 1628-1633. https://doi.org/10.1038/sj.leu.2403866

Multiple myeloma (MM) is an incurable B-cell cancer characterised by the monoclonal proliferation of tumour cells in the bone marrow (BM). It has been described that matrix metalloproteinases (MMPs) and especially MMP-9 is secreted by MM cells. In th... Read More about Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model.

Accessing employment (2005)
Presentation / Conference Contribution
McQuaid, R. W. (2005). Accessing employment.

Novel Framework for Automated Security Abstraction, Modelling, Implementation and Verification (2005)
Presentation / Conference Contribution
Saliou, L., Buchanan, W. J., Graves, J., & Munoz, J. (2005). Novel Framework for Automated Security Abstraction, Modelling, Implementation and Verification. In W. Hutchinson (Ed.),

This paper presents a novel framework for network security, and provides a complete solution to integrated security policies, which meets the objectives of an organisation, and also an automated verification process. The framework uses a security com... Read More about Novel Framework for Automated Security Abstraction, Modelling, Implementation and Verification.

Listening to local voices? International targets and decentralised education planning in Nepal. (2005)
Journal Article
Caddell, M. (2005). Listening to local voices? International targets and decentralised education planning in Nepal. International Journal of Educational Development, 25(4), 456-469. https://doi.org/10.1016/j.ijedudev.2005.04.010

This article draws on a case study of district educational planning in Nepal to explore how education for all priorities and targets impact on educational practice at the sub-national level. It raises questions about the extent of local ownership of... Read More about Listening to local voices? International targets and decentralised education planning in Nepal..

Through the Looking Glass: childhood in contemporary photography. (2005)
Exhibition / Performance
McMurdo, W., Benson, C., & Kearney, F. (2005). Through the Looking Glass: childhood in contemporary photography. 5 July 2005 - 28 September 2005. (Unpublished)

Throughout her adventures, Alice in Wonderland grapples with her identity. While this is a common feature of most children’s books, Alice’s questioning often invokes philosophical ideas. Similarly, contemporary photographers have focused their lens o... Read More about Through the Looking Glass: childhood in contemporary photography..

Coordinated parallel views for the exploratory analysis of microarray time-course data. (2005)
Presentation / Conference Contribution
Craig, P., Kennedy, J., & Cumming, A. (2005). Coordinated parallel views for the exploratory analysis of microarray time-course data. . https://doi.org/10.1109/CMV.2005.5

Microarray time-course data relate to the recorded activity of thousands of genes, in parallel, over multiple discrete points in time during a biological process. Existing techniques that attempt to support the exploratory analysis of this data rely... Read More about Coordinated parallel views for the exploratory analysis of microarray time-course data..

Online assessment and checking of SQL: detecting and preventing plagiarism. (2005)
Presentation / Conference Contribution
Russell, G., & Cumming, A. (2005). Online assessment and checking of SQL: detecting and preventing plagiarism.

The automatic checking of online assessments and tutorials offers a significant advantage to students. Such students can work out-of-hours, from home or work, managing their own time allocation. This allows formal practical sessions to concentrate on... Read More about Online assessment and checking of SQL: detecting and preventing plagiarism..

Rituals in children's cultures of consumption. (2005)
Presentation / Conference Contribution
Marsden, D. (2005, July). Rituals in children's cultures of consumption. Paper presented at Childhoods 2005: Children and youth in emerging and transforming societies

Consumption in children’s cultures is a much debated topic. Yet, few attempts have been
made to understand consumer culture from children’s own perspective, to investigate the
positive aspects of children’s relationships with consumer goods, and/or... Read More about Rituals in children's cultures of consumption..

A new short-term toxicity assay using Aspergillus awamori with recombinant aequorin gene (2005)
Journal Article
Kozlova, O., Zwinderman, M., & Christofi, N. (2005). A new short-term toxicity assay using Aspergillus awamori with recombinant aequorin gene. BMC Microbiology, 5, Article 40. https://doi.org/10.1186/1471-2180-5-40

Background
Most currently available short-term toxicity assays are based on bacterial cells. Therefore there is a need for novel eukaryotic microbial bioassays that will be relevant to higher eukaryotes such as animals and plants. Ca2+ is a universa... Read More about A new short-term toxicity assay using Aspergillus awamori with recombinant aequorin gene.