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All Outputs (52)

Addressing the Challenge of Polypharmacy (2019)
Journal Article
Mair, A., Wilson, M., & Dreischulte, T. (2020). Addressing the Challenge of Polypharmacy. Annual Review of Pharmacology and Toxicology, 60(1), 661-681. https://doi.org/10.1146/annurev-pharmtox-010919-023508

Polypharmacy describes the concomitant use of multiple medicines and represents a growing global challenge attributable to aging populations with an increasing prevalence of multimorbidity. Polypharmacy can be appropriate but is problematic when the... Read More about Addressing the Challenge of Polypharmacy.

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases (2019)
Journal Article
Bousquet, J. J., the ARIA Study Group, Schünemann, H. J., Togias, A., Erhola, M., Hellings, P. W., Zuberbier, T., Agache, I., Ansotegui, I. J., Anto, J. M., Bachert, C., Becker, S., Bedolla-Barajas, M., Bewick, M., Bosnic-Anticevich, S., Bosse, I., Boulet, L. P., Bourrez, J. M., Brusselle, G., Chavannes, N., …the MASK Study Group. (2019). Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases. Clinical and Translational Allergy, 9, Article 44 (2019). https://doi.org/10.1186/s13601-019-0279-2

Background
In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the healt... Read More about Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

The polypharmacy programme in Scotland: realistic prescribing (2019)
Journal Article
Mair, A., Wilson, M., & Dreischulte, T. (2019). The polypharmacy programme in Scotland: realistic prescribing. Prescriber, 30(8), 10-16. https://doi.org/10.1002/psb.1779

Since 2012, NHS Scotland has published a series of polypharmacy guidelines to help clinicians address the many medication‐related problems arising from multimorbidity. Here, Alpana Mair, Chair of the guideline group, Martin Wilson and Tobias Dreischu... Read More about The polypharmacy programme in Scotland: realistic prescribing.

Medication Safety in Transitions of Care: Technical Report (2019)
Report
World Health Organisation. (2019). Medication Safety in Transitions of Care: Technical Report. Geneva: WHO

Medication discrepancies impact almost every patient that moves across transitions of care, e.g. admission to or discharge from hospital. WHO urges countries to prioritise early and sustained action to reduce medication-related harm arising at transi... Read More about Medication Safety in Transitions of Care: Technical Report.

Polypharmacy and pharmacovigilance: How they relate and why it matters (2019)
Journal Article
Mair, A. (2019). Polypharmacy and pharmacovigilance: How they relate and why it matters. Uppsala Reports, 80, 12-13

Patients with multiple medical conditions – and, consequently, needing multiple medications – present one of the greatest challenges currently facing health services.

ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”: AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé), 
POLLAR (Impact of Air POLLution on Asthma and Rhinitis), 
GARD Demonstration project (2019)
Journal Article
Bosnic‐Anticevich, S., Costa, E., Menditto, E., Lourenço, O., Novellino, E., Bialek, S., Briedis, V., Mair, A., & Bousquet, J. (2019). ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”: AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé), 
POLLAR (Impact of Air POLLution on Asthma and Rhinitis), 
GARD Demonstration project. Allergy, 74(7), 1219-1236. https://doi.org/10.1111/all.13701

Pharmacists are trusted health care professionals. Many patients use over‐the‐counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in in... Read More about ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”: AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé), 
POLLAR (Impact of Air POLLution on Asthma and Rhinitis), 
GARD Demonstration project.

Age-Related Medicine (2019)
Journal Article
Wahlich, J., Orlu, M., Mair, A., Stegemann, S., & van Riet-Nales, D. (2019). Age-Related Medicine. Pharmaceutics, 11(4), Article 172. https://doi.org/10.3390/pharmaceutics11040172

A meeting organised by the Academy of Pharmaceutical Sciences focussed on the challenges of developing medicines for older adults. International experts discussed the complexity introduced by polypharmacy and multiple morbidities and how the risk–ben... Read More about Age-Related Medicine.

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study (2019)
Journal Article
Sheikh, A., De Vries, G., Anto, J. M., Annesi‐Maesano, I., Wickman, M., Hellings, P. W., Kuna, P., Cruz, A. A., Zuberbier, T., Pfaar, O., Bergmann, K. C., Kvedariene, V., Todo‐Bom, A. M., Morais‐Almeida, M., De Feo, G., Bousquet, J., Ivancevich, J. C., Kalayci, O., Gemicioğlu, B., Cingi, C., …Menditto, E. (2019). Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. Clinical and Experimental Allergy, 49(4), 442-460. https://doi.org/10.1111/cea.13333

Background
Mobile technology may help to better understand the adherence to treatment. MASK‐rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient‐centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is a... Read More about Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.

EuGMS Task and Finish group on Fall-Risk-Increasing Drugs (FRIDs): Position on Knowledge Dissemination, Management, and Future Research (2019)
Journal Article
Seppala, L. J., van der Velde, N., Masud, T., Blain, H., Petrovic, M., van der Cammen, T. J., Szczerbińska, K., Hartikainen, S., Kenny, R. A., Ryg, J., Eklund, P., Topinková, E., Mair, A., Laflamme, L., Thaler, H., Bahat, G., Gutiérrez-Valencia, M., Caballero-Mora, M., Landi, F., Emmelot-Vonk, M. H., …the EuGMS Special Interest Group on Pharmacology. (2019). EuGMS Task and Finish group on Fall-Risk-Increasing Drugs (FRIDs): Position on Knowledge Dissemination, Management, and Future Research. Drugs and Aging, 36(4), 299-307. https://doi.org/10.1007/s40266-018-0622-7

Falls are a major public health concern in the older population, and certain medication classes are a significant risk factor for falls. However, knowledge is lacking among both physicians and older people, including caregivers, concerning the role o... Read More about EuGMS Task and Finish group on Fall-Risk-Increasing Drugs (FRIDs): Position on Knowledge Dissemination, Management, and Future Research.

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology (2018)
Journal Article
Bousquet, J., Hellings, P. W., Agache, I., Amat, F., Annesi-Maesano, I., Mair, A., & Mobile Airways Sentinel Network (MASK) Study Group. (2019). Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology. Journal of Allergy and Clinical Immunology, 143(3), 864-879. https://doi.org/10.1016/j.jaci.2018.08.049

Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline by using the best approach to integrated care pathways using mobile technology in patients with allergic rhinitis (AR) and asthma multimorbidity. The proposed next phase o... Read More about Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

A case study of polypharmacy management in nine European countries: Implications for change management and implementation (2018)
Journal Article
McIntosh, J., Alonso, A., MacLure, K., Stewart, D., Kempen, T., Mair, A., Castel-Branco, M., Codina, C., Fernandez-Llimos, F., Fleming, G., Gennimata, D., Gillespie, U., Harrison, C., Illario, M., Junius-Walker, U., Kampolis, C. F., Kardas, P., Lewek, P., Malva, J., Menditto, E., …on behalf of the SIMPATHY Consortium. (2018). A case study of polypharmacy management in nine European countries: Implications for change management and implementation. PLOS ONE, 13(4), Article e0195232. https://doi.org/10.1371/journal.pone.0195232

Background
Multimorbidity and its associated polypharmacy contribute to an increase in adverse drug events, hospitalizations, and healthcare spending. This study aimed to address: what exists regarding polypharmacy management in the European Union (... Read More about A case study of polypharmacy management in nine European countries: Implications for change management and implementation.

A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people (2017)
Journal Article
Stewart, D., Gibson-Smith, K., MacLure, K., Mair, A., Alonso, A., Codina, C., Cittadini, A., Fernandez-Llimos, F., Fleming, G., Gennimata, D., Gillespie, U., Harrison, C., Junius-Walker, U., Kardas, P., Kempen, T., Kinnear, M., Lewek, P., Malva, J., McIntosh, J., Scullin, C., & Wiese, B. (2017). A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. PLOS ONE, 12(11), Article e0188348. https://doi.org/10.1371/journal.pone.0188348

Background
Inappropriate use of multiple medicines (inappropriate polypharmacy) is a major challenge in older people with consequences of increased prevalence and severity of adverse drug reactions and interactions, and reduced medicines adherence.... Read More about A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people.

Sustainable Implementation of Polypharmacy reviews as part of integrated care at Scale (2017)
Presentation / Conference Contribution
Mair, A. R., Kinnear, M., Hurding, S., Micheal, N., & Wilson, M. Sustainable Implementation of Polypharmacy reviews as part of integrated care at Scale

Medication is the most common form of intervention to prevent disease or slow disease progression, with guidelines for single diseases recommending evidence based drug treatments. There remains the mismatch between prescribing guidelines for speci... Read More about Sustainable Implementation of Polypharmacy reviews as part of integrated care at Scale.

Medication review and polypharmacy management in the hospital setting. The cases of Greece and Catalonia (2017)
Presentation / Conference Contribution
Gennimata, D., Kampolis, C. F., Vontetsianos, T., Mcintosh, J., Codina, C., Alonso, A., & Mair, A. Medication review and polypharmacy management in the hospital setting. The cases of Greece and Catalonia. Presented at 17th International Conference on Integrated Care, Dublin, Ireland

Introduction: Medication review and polypharmacy management, especially in the elderly, are key components of integrated care. Although polypharmacy management is often associated with the primary care setting, hospital clinicians, who are often memb... Read More about Medication review and polypharmacy management in the hospital setting. The cases of Greece and Catalonia.