Screening education and recognition in community pHarmacies of atrial fibrillation to prevent stroke in an ambulant population aged ≥65 years (SEARCH-AF stroke prevention study): a cross-sectional study protocol

Lowres, Nicole; Freedman, Saul Benedict; Redfern, Julie; McLachlan, Andrew; Krass, Ines; Bennett, Alexandra; Briffa, Thomas; Bauman, Adrian; Neubeck, Lis

Abstract

Background Atrial fibrillation (AF) is associated with a high risk of stroke and may often be asymptomatic. AF is commonly undiagnosed until patients present with sequelae, such as heart failure and stroke. Stroke secondary to AF is highly preventable with the use of appropriate thromboprophylaxis. Therefore, early identification and appropriate evidence-based management of AF could lead to subsequent stroke prevention. This study aims to determine the feasibility and impact of a community pharmacy-based screening programme focused on identifying undiagnosed AF in people aged 65 years and older.


Methods and analysis This cross-sectional study of community-based screening to identify undiagnosed AF will evaluate the feasibility of screening for AF using a pulse palpation and handheld single-lead electrocardiograph (ECG) device. 10 community pharmacies will be recruited and trained to implement the screening protocol, targeting a total of 1000 participants. The primary outcome is the proportion of people newly identified with AF at the completion of the screening programme. Secondary outcomes include level of agreement between the pharmacist's and the cardiologist's interpretation of the single-lead ECG; level of agreement between irregular rhythm identified with pulse palpation and with the single-lead ECG. Process outcomes related to sustainability of the screening programme beyond the trial setting, pharmacist knowledge of AF and rate of uptake of referral to full ECG evaluation and cardiology review will also be collected.

Citation

Lowres, N., Freedman, S. B., Redfern, J., McLachlan, A., Krass, I., Bennett, A., …Neubeck, L. (2012). Screening education and recognition in community pHarmacies of atrial fibrillation to prevent stroke in an ambulant population aged ≥65 years (SEARCH-AF stroke prevention study): a cross-sectional study protocol. BMJ Open, 2(3), Article e001355. https://doi.org/10.1136/bmjopen-2012-001355

• Journal Article Type: Article
• Acceptance Date: May 21, 2012
• Online Publication Date: Jun 25, 2012
• Publication Date: 2012
• Deposit Date: Nov 2, 2016
• Publicly Available Date: Nov 2, 2016
• Journal: BMJ Open
• Print ISSN: 2044-6055
• Electronic ISSN: 2044-6055
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 2
• Issue: 3
• Article Number: e001355
• DOI: https://doi.org/10.1136/bmjopen-2012-001355
• Keywords: Atrial fibrillation, stroke, adults,
• Public URL: http://researchrepository.napier.ac.uk/Output/411002